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Adalimumab |
Humira |
Image:Adalimumab.png Adalimumab Systematic (IUPAC) name Humanized anti-TNF antibody (D2E7) Identifiers CAS number 331731-18-1 ATC code L04AA17 PubChem ? DrugBank BTD00049 Chemical data Formula C6428H9912N1694O1987S46 Mol. weight 144190.3 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life 10-20 days. Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Adalimumab (Humira®) ...
Wikipedia - [full article]
Adalimumab Clinical Trials
- Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Active Ankylosing Spondylitis
ClinicalTrials.gov Identifier: NCT00085644 - Active, not recruiting
Ankylosing Spondylitis
- A Study of Adalimumab to Treat Sarcoidosis of the Skin
ClinicalTrials.gov Identifier: NCT00274352 - Recruiting
Sarcoidosis
- Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00195676 - Active, not recruiting
Psoriasis
- Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00235820 - Active, not recruiting
Psoriasis
- Efficacy, Safety, Immunogenicity and Effect on Immune Response of Adalimumab Following Subcutaneous Administration in Patients With Active RA Treated Concomitantly With MTX.
ClinicalTrials.gov Identifier: NCT00195702 - Active, not recruiting
Rheumatoid Arthritis
- Long-Term Open-Label Safety and Efficacy Study of Adalimumab in Subjects With Crohn’s Disease
ClinicalTrials.gov Identifier: NCT00195715 - Active, not recruiting
Crohn’s Disease
- Effects of Adalimumab on Mucosal Healing in Subjects With Crohn's Disease Involving the Colon
ClinicalTrials.gov Identifier: NCT00348283 - Active, not recruiting
Crohn's Disease
- A Study of Adalimumab for the Induction of Clinical Remission in Japanese Subjects With Crohn's Disease
ClinicalTrials.gov Identifier: NCT00445939 - Active, not recruiting
Crohn's Disease
- A Study of the Human Anti-TNF Monoclonal Antibody Adalimumab in Canadian Subjects With Moderate to Severe Crohn’s Disease (ACCESS)
ClinicalTrials.gov Identifier: NCT00427921 - Active, not recruiting
Crohn’s Disease
- A Study to Assess the Safety and Efficacy of Adalimumab When Added to Inadequate Standard Anti-Rheumatic Therapy in Patients With Active Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00448383 - Active, not recruiting
Rheumatoid Arthritis
- A Canadian Open-Label Study to Evaluate the Safety and Effectiveness of Adalimumab When Added to Inadequate Therapy for the Treatment of Psoriatic Arthritis (PsA) (ACCLAIM)
ClinicalTrials.gov Identifier: NCT00427362 - Active, not recruiting
Psoriatic Arthritis
- Safety and Efficacy of Adalimumab in Patients With Active Ankylosing Spondylitis
ClinicalTrials.gov Identifier: NCT00195819 - Active, not recruiting
Ankylosing Spondylitis
- Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00235833 - Active, not recruiting
Rheumatoid Arthritis
- Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00235872 - Active, not recruiting
Rheumatoid Arthritis
- Remission in Subjects with Crohn's Disease
ClinicalTrials.gov Identifier: NCT00055497 - Active, not recruiting
Crohn's Disease
- Adalimumab in Uveitis Refractory to Conventional Therapy (ADUR Trial)
ClinicalTrials.gov Identifier: NCT00348153 - Recruiting
Uveitis
- A Canadian Open-Label Access Program to Evaluate Adalimumab When Added to Inadequate Therapy for the Treatment of Psoriasis
ClinicalTrials.gov Identifier: NCT00513370 - Recruiting
Psoriasis
- Danish Multicenter Study of Adalimumab in Spondyloarthritis
ClinicalTrials.gov Identifier: NCT00477893 - Recruiting
Spondyloarthritis
- Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects with Crohn's Disease
ClinicalTrials.gov Identifier: NCT00105300 - Completed
Crohn's Disease
- Trial of Adalimumab in Progressive Sarcoidosis
ClinicalTrials.gov Identifier: NCT00311246 - Recruiting
Sarcoidosis
- Adalimumab in Severe and Acute Sciatica
ClinicalTrials.gov Identifier: NCT00470509 - Recruiting
Sciatica
- Comparator With Adalimumab and MTX Versus MTX in Subjects With Early Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00195663 - Active, not recruiting
Early Rheumatoid Arthritis
- Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis
ClinicalTrials.gov Identifier: NCT00291915 - Recruiting
Rheumatoid Arthritis; Arthritis
- Adalimumab for the Induction and Maintenance of Clinical Remission in Subjects with Crohn's Disease
ClinicalTrials.gov Identifier: NCT00077779 - Completed
Crohn's Disease
- Long-Term Open-Label Safety and Efficacy Study of Adalimumab in Subjects With Ulcerative Colitis
ClinicalTrials.gov Identifier: NCT00573794 - Recruiting
Ulcerative Colitis
- A 5-Year Registry Study of Humira® (Adalimumab) in Subjects With Moderately to Severely Active Crohn's Disease (CD)
ClinicalTrials.gov Identifier: NCT00524537 - Recruiting
Crohn's Disease
- An Open-Label Study of Adalimumab for the Induction and Maintenance of Clinical Remission in Subjects With Moderate to Severe Crohn's Disease
ClinicalTrials.gov Identifier: NCT00409617 - Recruiting
Crohn's Disease
- Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Acute Ulcerative Colitis
ClinicalTrials.gov Identifier: NCT00385736 - Recruiting
Ulcerative Colitis
- Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Acute Ulcerative Colitis
ClinicalTrials.gov Identifier: NCT00408629 - Recruiting
Ulcerative Colitis
- Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Crohn's Disease
ClinicalTrials.gov Identifier: NCT00409682 - Recruiting
Crohn's Disease
- A Study of Adalimumab for the Maintenance of Clinical Remission in Japanese Subjects With Crohn's Disease
ClinicalTrials.gov Identifier: NCT00445432 - Recruiting
Crohn's Disease
- A Study to Determine the Optimal Protocol for Treatment Initiation With Methotrexate and Adalimumab Combination Therapy in Patients With Early Rheumatoid Arthritis - OPTIMA
ClinicalTrials.gov Identifier: NCT00420927 - Recruiting
Rheumatoid Arthritis
- A Study to Assess the Safety and Efficacy of Adalimumab Administered as Subcutaneous Injections in Adult Chinese Rheumatoid Arthritis Subjects Treated With Methotrexate
ClinicalTrials.gov Identifier: NCT00538902 - Recruiting
Rheumatoid Arthritis
- Adalimumab in Combination With Topical Treatment (Calcipotriol/Betamethasone) in Subjects With Moderate to Severe Psoriasis and Insufficient Response to Classic Systemic Treatment
ClinicalTrials.gov Identifier: NCT00574249 - Recruiting
Chronic Plaque Psoriasis
- Positron Emission Tomography in Rheumatoid Arthritis With Adalimumab (PETRA)
ClinicalTrials.gov Identifier: NCT00497614 - Recruiting
Rheumatoid Arthritis
- Comparison of Adalimumab and Infliximab Treatment of Rheumatoid Arthritis.
ClinicalTrials.gov Identifier: NCT00216177 - Recruiting
Rheumatoid Arthritis
- Open-Label Adalimumab for Ulcerative Colitis Patients
ClinicalTrials.gov Identifier: NCT00421642 - Recruiting
Ulcerative Colitis
- Open Label Study of Adalimumab in Subjects Who Have a Sub-Optimal Response to Systemic Therapy or Phototherapy
ClinicalTrials.gov Identifier: NCT00566722 - Not yet recruiting
Psoriasis
- A Phase II Study of the Human Anti-TNF Antibody Adalimumab for the Induction of Clinical Remission in Subjects with Crohn's Disease
ClinicalTrials.gov Identifier: NCT00055523 - Completed
Crohn's Disease
- Predictors of the Response to Etanercept and Adalimumab in Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00234234 - Recruiting
Rheumatoid Arthritis
- Adalimumab (Humira) in the Treatment of Refractory Non-Infectious Uveitis
ClinicalTrials.gov Identifier: NCT00525902 - Not yet recruiting
Uveitis
- Study to Evaluate the Efficacy of Adalimumab in Patients With Erosive Osteoarthritis of the Interphalangeal Finger Joints
ClinicalTrials.gov Identifier: NCT00296894 - Not yet recruiting
Erosive Osteo-Arthritis
- Study of the Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00048542 - Completed
Arthritis, Juvenile Rheumatoid
- Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00237887 - Completed
Psoriasis
- Adalimumab in Adult Japanese Subjects With Moderate to Severe Chronic Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00338754 - Completed
Psoriasis
- A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis
ClinicalTrials.gov Identifier: NCT00185562 - Completed
Osteoarthritis
- Safety and Efficacy of Adalimumab in Patients With Moderate to Severely Active Psoriatic Arthritis
ClinicalTrials.gov Identifier: NCT00195689 - Completed
Psoriatic Arthritis
- Safety and Efficacy Study of Adalimumab in Patients With Active Psoriatic Arthritis (PsA)
ClinicalTrials.gov Identifier: NCT00235885 - Completed
Psoriatic Arthritis
- Treatment of the Human Anti-TNF Monoclonal Antibody Adalimumab in Moderate to Severe Crohn's Disease With Previous Exposure to Infliximab (CHOICE)
ClinicalTrials.gov Identifier: NCT00338650 - Completed
Crohn's Disease
- Adalimumab Administered in Korean Rheumatoid Arthritis Subjects Treated With Methotrexate
ClinicalTrials.gov Identifier: NCT00235859 - Completed
Rheumatoid Arthritis
- An Open-Label Study to Evaluate the Response to Adalimumab in Patients With Active Ankylosing Spondylitis Who Have Failed Standard Therapy or TNF-Alpha Inhibitors (RHAPSODY)
ClinicalTrials.gov Identifier: NCT00478660 - Completed
Ankylosing Spondylitis
- Quality of Life Study With Adalimumab in Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00234936 - Completed
Rheumatoid Arthritis
- Study of Human Anti-TNF Monoclonal Antibody D2E7 in Subjects with Active Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00049751 - Completed
Rheumatoid Arthritis
- A Long Term Roll-Over Study to Investigate the Efficacy and Safety of Adalimumab Given Long-Term to Patients With Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00233571 - Completed
Rheumatoid Arthritis
- Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00234845 - Completed
Rheumatoid Arthritis
- TNFalfa Blocking Treatment of Spondylarthropathies
ClinicalTrials.gov Identifier: NCT00133315 - Completed
Spondylarthropathies; Ankylosing Spondylitis; Psoriatic Arthritis
- Open-Label Steroid Reduction Study of Adalimumab With Methotrexate in Patients With Active Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00233558 - Terminated
Rheumatoid Arthritis
Resources
- Adalimumab (Drug Digest)
- Humira (Drug Digest)
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