Estradiol and Norethindrone Acetate Oral |
Activella |
for the prevention of osteoporosis associated with menopause. Activella is a continuous-combined once daily tablet combining estrogen (1 mg estradiol) and progestin (0.5 mg norethindrone acetate). It was previously approved by the FDA for the treatment of moderate to severe vasomotor symptoms associated with menopause and for vulvar and vaginal atrophy associated with menopause. Use of the product is restricted to women with an intact uterus.
... ESTRADIOL; NORETHINDRONE (Activella) tablets are a mixture of a natural estrogen female hormone and a progestin. Estradiol is essential for maintaining normal female functions and is normally produced by the ovaries. After menopause, the ovaries decrease their production of this hormone. Estradiol can help relieve symptoms of the menopause (hot flashes, night sweats, mood changes, and vaginal dryness and irritation), and also help to prevent the onset of osteoporosis (a loss of bone mass, so that bones become brittle and easily broken). Norethindrone is a progestin that is helpful in reducing overgrowth of the lining of the uterus (the endometrium), which may help reduce your risk of endometrial cancer. Generic estradiol; norethindrone tablets are not yet available. ...
Resources
- Activella (Drug Digest)
- Estradiol and Norethindrone Acetate Oral (Drug Digest)

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