Article: Acetohexamide

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Acetohexamide
Systematic (IUPAC) name
1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea
Identifiers
CAS number 968-81-0
ATC code A10BB31
PubChem 1989
DrugBank APRD00773
Chemical data
Formula C15H20N2O4S
Mol. weight 324.396 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 90%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Acetohexamide is a sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone. Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition [1].


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