Bupropion (amfebutamone) is an antidepressant of the aminoketone class, chemically unrelated to tricyclics or SSRIs. It is similar in structure to the stimulant cathinone, and to phenethylamines in general.

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... BUPROPION (Wellbutrin® SR) is an antidepressant, a medicine that helps to lift mental depression. Bupropion acts differently from other antidepressants and may be useful for treating patients who have had unusual or limiting effects from other antidepressants. Occasionally bupropion is prescribed for other behavioral or emotional problems. Generic bupropion sustained-release tablets for Wellbutrin® SR are available. ...
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