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Sildenafil |
sildenafil citrate; Viagra |
Sildenafil Systematic (IUPAC) name 1-[4-ethoxy-3-(6,7-dihydro-1-methyl- 7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl) phenylsulfonyl]-4-methylpiperazine citrate Identifiers CAS number 171599-83-0 ATC code G04BE03 PubChem 5281023 DrugBank APRD00556 Chemical data Formula C22H30N6O4S · C6H8O7 Mol. weight base: 474.6 g/mol salt: 666.7 g/mol SMILES O=S(=O)(N1CCN(C)CC1)c4cc(C=2NC(=O) c3n(C)nc(CCC)c3N=2)c(OCC)cc4 Pharmacokinetic data Bioavailability ? Me ...
Wikipedia - [full article]
Sildenafil Clinical Trials
- Open Label Extension Study Evaluating Sildenafil Citrate When Used In Combination with Epoprostenol In PAH
ClinicalTrials.gov Identifier: NCT00147641 - Active, not recruiting
Pulmonary Hypertension
- Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)
ClinicalTrials.gov Identifier: NCT00303459 - Recruiting
Pulmonary Hypertension
- Long Term Extension Study Evaluating Safety of Sildenafil Citrate When Used to Treat PAH in Children
ClinicalTrials.gov Identifier: NCT00159874 - Recruiting
Pulmonary Hypertension
- A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children with Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00159913 - Recruiting
Pulmonary Hypertension
- Assessment Of Sildenafil On Erectile Function And Intercourse Satisfaction And To Validate A New Subject Questionnaire
ClinicalTrials.gov Identifier: NCT00147628 - Completed
Impotence
- Randomized Study of Sildenafil Citrate During & After Radiotherapy for Erectile Ftn Vs Radiotherapy for Prostate Ca
ClinicalTrials.gov Identifier: NCT00142506 - Recruiting
Prostate Cancer
- Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia
ClinicalTrials.gov Identifier: NCT00056433 - Active, not recruiting
Sickle Cell Anemia
- The Pharmacological Basis for the Increase in Visual Time Constants Induced by Single Oral Doses of Sildenafil
ClinicalTrials.gov Identifier: NCT00463957 - Active, not recruiting
Erectile Dysfunction
- Chronic Sildenafil for Severe Diaphragmatic Hernia
ClinicalTrials.gov Identifier: NCT00133679 - Recruiting
Hernia, Diaphragmatic; Hypertension, Pulmonary; Hypoplasia, Lung
- Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers Syndrome
ClinicalTrials.gov Identifier: NCT00303004 - Active, not recruiting
Eisenmenger Syndrome
- Effect of Sildenafil on Endothelial Function
ClinicalTrials.gov Identifier: NCT00297544 - Recruiting
Impotence
- Sildenafil for Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov Identifier: NCT00104637 - Recruiting
Pulmonary Disease, Chronic Obstructive; Emphysema
- Hemodynamic Response After Six Months of Sildenafil
ClinicalTrials.gov Identifier: NCT00483626 - Recruiting
Pulmonary Arterial Hypertension
- Use of Sildenafil (Viagra) in Diabetic Men With Erectile Dysfunction: the Impact on Blood Vessels
ClinicalTrials.gov Identifier: NCT00199563 - Recruiting
Impotence
- Effect of Sildenafil on Quality of Sexual Life in Mild to Normally Sexually Functioning Males
ClinicalTrials.gov Identifier: NCT00313898 - Recruiting
Erectile Dysfunction
- Sildenafil After the Fontan Operation
ClinicalTrials.gov Identifier: NCT00507819 - Recruiting
Hypoplastic Left Heart Syndrome; Tricuspid Atresia; Other Single Ventricle Anatomy
- Effect of Nightly vs. Prn Sildenafil on Early Return of Erectile Function Following Laparoscopic Radical Prostatectomy
ClinicalTrials.gov Identifier: NCT00511498 - Recruiting
Prostate Cancer
- The Effect of Sildenafil in Preterm Infants With Evolving Chronic Lung Disease
ClinicalTrials.gov Identifier: NCT00431418 - Recruiting
Lung Diseases
- Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
ClinicalTrials.gov Identifier: NCT00334490 - Recruiting
Pulmonary Hypertension
- Sildenafil to Treat HIV-Associated Pulmonary Hypertension
ClinicalTrials.gov Identifier: NCT00327080 - Recruiting
HIV
- The Efficacy and Safety of Sildenafil Citrate Used in Combination with Intravenous Epoprostenol in PAH
ClinicalTrials.gov Identifier: NCT00159861 - Completed
Pulmonary Hypertension
- The “VISION” Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00302211 - Recruiting
Pulmonary Hypertension
- Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00323297 - Recruiting
Pulmonary Hypertension
- Open Label Study of Sildenafil in Patients With Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00454207 - Recruiting
Pulmonary Hypertension
- Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in COPD
ClinicalTrials.gov Identifier: NCT00491803 - Recruiting
COPD; Pulmonary Hypertension
- Sildenafil and Alprostadil in Treating Patients Undergoing Bilateral Nerve-Sparing Robotic-Assisted Prostatectomy for Nonmetastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00544076 - Recruiting
Prostate Cancer; Sexual Dysfunction and Infertility
- Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass?
ClinicalTrials.gov Identifier: NCT00350441 - Recruiting
Cardiopulmonary Bypass
- Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov Identifier: NCT00359736 - Recruiting
Fibrosis, Pulmonary; Alveolitis, Fibrosing; Hypertension, Pulmonary; Exercise, Aerobic
- Study of Sildenafil in Advanced Heart Failure.
ClinicalTrials.gov Identifier: NCT00309790 - Recruiting
Congestive Heart Failure
- Sildenafil (Viagra) Treatment of Subacute Ischemic Stroke
ClinicalTrials.gov Identifier: NCT00452582 - Recruiting
Ischemic Stroke
- Therapeutic Effect of Sildenafil in Patients With Coronary Vasospasm
ClinicalTrials.gov Identifier: NCT00454714 - Recruiting
Coronary Vasospasm
- Study to Assess the Longterm Safety of Sildenafil Citrate in Patients with Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00159887 - Completed
Pulmonary Hypertension
- Viagra in the Treatment of Primary Dysmenorrhea
ClinicalTrials.gov Identifier: NCT00123162 - Recruiting
Dysmenorrhea
- Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov Identifier: NCT00517933 - Recruiting
Pulmonary Fibrosis; Hypertension, Pulmonary
- Treatment of Erectile Dysfunction (ED) in Patients Treated for Prostate Cancer
ClinicalTrials.gov Identifier: NCT00075127 - Recruiting
Prostate Cancer
- Cervical or Endomterial Cancer and Sexual Health Study, Phase 1 & 2
ClinicalTrials.gov Identifier: NCT00134316 - Recruiting
Sexual Dysfunctions, Psychological
- To Assess The Efficacy And Safety Of Oral Sildenafil In The Treatment Of Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00430716 - Not yet recruiting
Hypertension, Pulmonary
- Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
ClinicalTrials.gov Identifier: NCT00080808 - Active, not recruiting
perioperative/postoperative complications; sexual dysfunction and infertility; sexuality and reproductive issues; adenocarcinoma of the prostate; ...
- Sildenafil For Meniere''s Disease
ClinicalTrials.gov Identifier: NCT00145483 - Completed
Meniere''s Disease
- Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease
ClinicalTrials.gov Identifier: NCT00492531 - Recruiting
Sickle Cell Disease; Pulmonary Hypertension
- Efficacy of Type-5 Phosphodiesterase Inhibitors in Primary and Secondary Pulmonary Hypertension
ClinicalTrials.gov Identifier: NCT00155714 - Recruiting
primary and secondary pulmonary hypertension
- Interaction Between Fluvoxamine and Sildenafil
ClinicalTrials.gov Identifier: NCT00175981 - Completed
Healthy
- Healthy Volunteer Study of Sildenafil Effects Upon Vision
ClinicalTrials.gov Identifier: NCT00251784 - Completed
Blindness
- Study For Which Treatment, Tadalafil or Sildenafil, is Preferred For Problems Getting or Maintaining an Erection
ClinicalTrials.gov Identifier: NCT00547092 - Completed
Impotence
- Studying the Preference of Tadalafil to Sildenafil in Men With Problems Getting an Erection Across Nations
ClinicalTrials.gov Identifier: NCT00547287 - Completed
Impotence
- Study to Determine a Preference Between Sildenafil or Tadalafil Treatment for Problems Getting an Erection
ClinicalTrials.gov Identifier: NCT00547352 - Completed
Impotence
- Sildenafil and Pulmonary Artery Pressure
ClinicalTrials.gov Identifier: NCT00145938 - Terminated
Pulmonary Hypertension
- Quality of Erection Study
ClinicalTrials.gov Identifier: NCT00159900 - Completed
Impotence
- Effect of Regular Sildenafil on Blood Pressure and Arterial Function in Hypertension
ClinicalTrials.gov Identifier: NCT00317421 - Completed
Hypertension
- A Placebo-Controlled Single-Dose Trial of Sildenafil in Schizophrenia
ClinicalTrials.gov Identifier: NCT00455715 - Completed
Schizophrenia
- QEQ Treatment Responsiveness Evaluation Study
ClinicalTrials.gov Identifier: NCT00151463 - Completed
Impotence
- Mild ED II
ClinicalTrials.gov Identifier: NCT00143260 - Completed
Impotence
- Blood Pressure Interaction Between Sildenafil and Sublingual Glyceryl Trinitrate (GTN) in Men With Angina
ClinicalTrials.gov Identifier: NCT00479908 - Completed
Angina Pectoris
- Sildenafil in Treating Erectile Dysfunction in Patients With Prostate Cancer
ClinicalTrials.gov Identifier: NCT00057759 - Completed
sexual dysfunction and infertility; sexuality and reproductive issues; radiation toxicity; stage II prostate cancer; stage III prostate cancer; ...
- Sildenafil Citrate for the Treatment of Established Pre-Eclampsia
ClinicalTrials.gov Identifier: NCT00141310 - Terminated
Pre-Eclampsia
- Mild ED I
ClinicalTrials.gov Identifier: NCT00137072 - Completed
Erectile Dysfunction
- Evaluation of the Index of Sexual Life Questionnaire
ClinicalTrials.gov Identifier: NCT00245596 - Completed
Erectile Dysfunction
- Acute Effects of Sildenafil on Endothelial Function in People With Diabetes
ClinicalTrials.gov Identifier: NCT00527995 - Completed
Type 2 Diabetes Mellitus; Endothelial Dysfunction
- Study of Sildenafil for Treatment of SSRI-Antidepressant Sexual Dysfunction in Women
ClinicalTrials.gov Identifier: NCT00375297 - Completed
Sexual Dysfunction; Depression
- Study of Sildenafil in Patient With Heart Failure.
ClinicalTrials.gov Identifier: NCT00309816 - Completed
Congestive Heart Failure
- PDE5-Inhibition With Sildenafil in Chronic Heart Failure
ClinicalTrials.gov Identifier: NCT00407446 - Completed
Heart Failure
- An Assessment Of Efficacy, Safety & Toleration Of An Investigational New Drug In Patients With Erectile Dysfunction
ClinicalTrials.gov Identifier: NCT00273416 - Completed
Impotence
- The Effect of Sildenafil Citrate (Viagra® (Registered Trademark)) on Brain Blood Flow in Multiple Sclerosis Patients
ClinicalTrials.gov Identifier: NCT00094068 - Completed
Multiple Sclerosis
- To Yield Further Information On The Efficacy And Safety Of Viagra Among Subjects With Arterial Hypertension .
ClinicalTrials.gov Identifier: NCT00150358 - Completed
Erectile Dysfunction; Hypertension
- Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension
ClinicalTrials.gov Identifier: NCT00352482 - Completed
Pulmonary Fibrosis; Hypertension, Pulmonary
- Sildenafil Citrate in Waldenstrom's Macroglobulinemia
ClinicalTrials.gov Identifier: NCT00165295 - Terminated
Waldenstrom's Macroglobulinemia
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