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Montelukast |
montelukast sodium; Singulair |
Image:Singulair.jpg Montelukast Systematic (IUPAC) name 2-[1-[[(1R)-1-[3-[2-(7-chloroquinolin-2-yl)ethenyl] phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl] sulfanylmethyl]cyclopropyl]acetic acid Identifiers CAS number 158966-92-8 ATC code R03DC03 PubChem 60951 DrugBank APRD00434 Chemical data Formula C35H36NClO3S Mol. weight 586.184 g/mol Pharmacokinetic data Bioavailability ? Protein binding 99% Metabolism Hepatic (CYP3A4 and CYP2C9-mediated) ...
Wikipedia - [full article]
Montelukast Clinical Trials
- Montelukast in Very Low Birthweight Infants
ClinicalTrials.gov Identifier: NCT00492102 - Recruiting
Bronchopulmonary Dysplasia; Pharmacokinetics of Montelukast
- A Study to Assess the Effect of Montelukast Sodium with Concomitant Administration of Inhaled Budesonide in Asthmatic Patients.
ClinicalTrials.gov Identifier: NCT00140946 - Active, not recruiting
Asthma
- Ramatroban/Montelukast Versus Montelukast/Placebo on the Early Allergic Reaction in Asthma Sensitive to House Dust Mite
ClinicalTrials.gov Identifier: NCT00311051 - Recruiting
Asthma
- Use of Montelukast to Treat Children with Mild to Moderate Acute Asthma
ClinicalTrials.gov Identifier: NCT00213252 - Recruiting
Asthma, Bronchial
- Effects of Montelukast on Early Life Wheezing
ClinicalTrials.gov Identifier: NCT00115297 - Recruiting
Lung Diseases; Asthma
- Montelukast in the Treatment of Duodenal Eosinophilia
ClinicalTrials.gov Identifier: NCT00148603 - Recruiting
eosinophilic gastroenteritis; Dyspepsia
- Airway Responses to Montelukast and Desloratadine.
ClinicalTrials.gov Identifier: NCT00424580 - Active, not recruiting
Asthma
- The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic Rhinitis
ClinicalTrials.gov Identifier: NCT00119015 - Recruiting
Rhinitis, Allergic, Perennial
- Montelukast Added to Standard Therapy for Acute Asthma in Children Age 6-14 Years
ClinicalTrials.gov Identifier: NCT00353184 - Active, not recruiting
Asthma
- Predicting the Response to Montelukast by Genetic Variation in Asthmatics
ClinicalTrials.gov Identifier: NCT00116324 - Completed
Asthma
- Montelukast Asthmatic Smoker Study
ClinicalTrials.gov Identifier: NCT00284856 - Recruiting
Asthma
- Transporter Mediated Uptake of Montelukast
ClinicalTrials.gov Identifier: NCT00513760 - Recruiting
Asthma
- Montelukast in Mild Asthmatic Children With Allergic Rhinitis
ClinicalTrials.gov Identifier: NCT00442559 - Active, not recruiting
Asthma; Allergic Rhinitis
- Comparison of Combination Therapy: Montelukast and Inhaled Steroid on Exercise Induced Bronchoconstriction
ClinicalTrials.gov Identifier: NCT00462592 - Recruiting
Asthma
- Trial of Asthma Patient Education (TAPE)
ClinicalTrials.gov Identifier: NCT00148408 - Active, not recruiting
Asthma
- Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis
ClinicalTrials.gov Identifier: NCT00488176 - Active, not recruiting
Seasonal Allergic Rhinitis
- Leukotriene Polymorphisms and Montelukast Response - Ancillary to LoDo Trial
ClinicalTrials.gov Identifier: NCT00046644 - Active, not recruiting
Asthma; Lung Diseases
- A Study to Determine the Effect of Montelukast Sodium as an Episode Modifier in the Treatment of Infrequent Episodic Asthma in Children
ClinicalTrials.gov Identifier: NCT00140881 - Completed
Asthma
- Effects of Mometasone Furoate Dry Powder Inhaler, Fluticasone Propionate, and Montelukast on Bone Mineral Density in Asthmatics (Study P03418AM4)
ClinicalTrials.gov Identifier: NCT00394355 - Recruiting
Asthma
- Effect of Montelukast on Experimentally-Induced RV16 Infection in Asthma
ClinicalTrials.gov Identifier: NCT00359073 - Recruiting
Asthma
- An Approved Drug to Study a New Indication for Allergic Rhinitis
ClinicalTrials.gov Identifier: NCT00127647 - Active, not recruiting
Rhinitis, Allergic, Seasonal
- Effect of Addition of Oral Montelukast to Standard Treatment in Acute Moderate to Severe Asthma in Children
ClinicalTrials.gov Identifier: NCT00565955 - Recruiting
Bronchial Asthma
- A Pilot Study of Montelukast Sodium (Singulair) in Older Adults with Asthma or Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov Identifier: NCT00162864 - Completed
Asthma; COPD
- The Leukotriene Modifier Or Corticosteroid or Corticosteroid-Salmeterol Trial (The LOCCS Trial)
ClinicalTrials.gov Identifier: NCT00156819 - Active, not recruiting
Asthma
- A Study to Compare Effectiveness of Montelukast Sodium with Comparator in Mild to Moderate Persistent Asthmatics
ClinicalTrials.gov Identifier: NCT00157937 - Completed
Asthma; Allergic Rhinitis
- Montelukast in ENL Reaction
ClinicalTrials.gov Identifier: NCT00406861 - Not yet recruiting
Erythema Nodosum Leprosum; Leprosy
- Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens
ClinicalTrials.gov Identifier: NCT00557284 - Recruiting
Atopic Dermatitis
- Montelukast With Status Asthmaticus, Ages 6-18
ClinicalTrials.gov Identifier: NCT00494572 - Recruiting
Status Asthmaticus; Asthma
- Does Montelukast Have an Affect on the Function of the Artery in Patients With Heart Disease
ClinicalTrials.gov Identifier: NCT00351364 - Recruiting
Coronary Artery Disease; Acute Coronary Syndrome
- Montelukast With Status Asthmaticus, Ages 2-5
ClinicalTrials.gov Identifier: NCT00491790 - Recruiting
Status Asthmaticus; Asthma
- Two Investigational Drugs in the Prevention of Airway Constriction Brought on by Exercise in Asthmatic Patients
ClinicalTrials.gov Identifier: NCT00127166 - Recruiting
Exercise-Induced Asthma
- Effect of Montelukast on the Expression and Variation of TGF-β for Children With Mild Persistent Asthma
ClinicalTrials.gov Identifier: NCT00536705 - Not yet recruiting
Asthma
- The Effect of Montelukast on Difficulty in Breathing After Exercise in Pediatric Patients
ClinicalTrials.gov Identifier: NCT00534976 - Not yet recruiting
Exercise-Induced Bronchoconstriction (EIB)
- The Effect of Montelukast in Patients With Chronic Cough and Bronchial Hyperreactivity
ClinicalTrials.gov Identifier: NCT00453765 - Recruiting
Cough; Bronchial Hyperreactivity
- Trial of Montelukast in Eosinophilic Esophagitis
ClinicalTrials.gov Identifier: NCT00511316 - Recruiting
Eosinophilic Esophagitis
- Montelukast as Prophylaxis for Upper Respiratory Tract Infections in Children: a Randomised, Double-Blind, Placebo-Controlled Study
ClinicalTrials.gov Identifier: NCT00551382 - Not yet recruiting
Upper Respiratory Tract Infection
- Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes
ClinicalTrials.gov Identifier: NCT00375232 - Not yet recruiting
Exercise-Induced Bronchospasm
- Montelukast Back to School
ClinicalTrials.gov Identifier: NCT00461032 - Completed
Asthma
- Montelukast on Airway Inflammation
ClinicalTrials.gov Identifier: NCT00496496 - Completed
Asthma
- Montelukast Post-Marketing Comparative Study With Ketotifen
ClinicalTrials.gov Identifier: NCT00446056 - Completed
Asthma
- Pediatric ADVAIR DISKUS Versus Oral Montelukast Chewable Tablets
ClinicalTrials.gov Identifier: NCT00328718 - Completed
Asthma
- Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds
ClinicalTrials.gov Identifier: NCT00189475 - Completed
Upper Respiratory Infection
- Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing SAR Symptoms in Ragweed Sensitive Subjects
ClinicalTrials.gov Identifier: NCT00295022 - Completed
Rhinitis, Allergic, Seasonal
- Compare the Efficacy of Levocetirizine to Montelukast in Reducing Symptoms of SAR in Sensitive Subjects Exposed to Ragweed Pollen
ClinicalTrials.gov Identifier: NCT00315523 - Completed
Rhinitis, Allergic, Seasonal
- Effect of Loratadine/Montelukast Combination on Congestion in SAR Patients Exposed to Pollen in an EEU (Study P04822)(COMPLETED)
ClinicalTrials.gov Identifier: NCT00423995 - Completed
Seasonal Allergic Rhinitis
- To Evaluate the Inflammatory Markers in Adult Patients With Asthma Associated With Allergic Rhinitis Receiving Montelukast Therapy
ClinicalTrials.gov Identifier: NCT00398151 - Completed
Asthma
- Montelukast in Modulating Exacerbations of Asthma in Children
ClinicalTrials.gov Identifier: NCT00196547 - Completed
Asthma
- Montelukast in Acute RSV Bronchiolitis
ClinicalTrials.gov Identifier: NCT00524693 - Completed
Bronchiolitis
- The Effect of Glucocorticosteroid and Vitamin D3 Administration and Montelukast Treatment on Early Clinical and Immunological Effect of Allergen-Specific Immunotherapy in Asthmatic Children
ClinicalTrials.gov Identifier: NCT00504946 - Completed
Asthma
- Montelukast as a Controller of Atopic Syndrome
ClinicalTrials.gov Identifier: NCT00559546 - Completed
Seasonal Allergic Rhinitis; Allergic Conjunctivitis; Atopic Eczema; Asthma
- Long-term Safety Performance of Fexofenadine in Asthma
ClinicalTrials.gov Identifier: NCT00045955 - Completed
Asthma
- Effects of Loratadine/Montelukast vs Pseudoephedrine and Placebo in Patients With Seasonal Allergic Rhinitis (Study P04095) (COMPLETED)
ClinicalTrials.gov Identifier: NCT00319995 - Completed
Rhinitis, Allergic, Seasonal
- A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in Children
ClinicalTrials.gov Identifier: NCT00189462 - Completed
Acute Otitis Media; Otitis Media; Ear Infection
- CARE Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS)
ClinicalTrials.gov Identifier: NCT00471809 - Terminated
Asthma
Resources
- Montelukast (Drug Digest)
- Singulair (Drug Digest)
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