Fluoxetine |
Prozac; Prozac Weekly; Sarafem |
Clinical Trial: Fluoxetine as a Quit Smoking AID for Depression Prone
This study has been completed.
Purpose
| Condition | Intervention |
|---|---|
| Cardiovascular Diseases Heart Diseases | Drug: fluoxetine Behavior: cognitive behavioral therapy |
MedlinePlus related topics: Heart Diseases; Vascular Diseases
Study Type: Interventional
Study Design: Prevention, Double-Blind, Placebo Control
Study start: February 1998; Study completion: January 2002
Eligibility
Location Information
Bonnie Spring, U.S. Dept/Vets Affairs Med Ctr.
More Information
Publications
Hitsman B, Spring B, Wolf W, Pingitore R, Crayton JW, Hedeker D. Effects of acute tryptophan depletion on negative symptoms and smoking topography in nicotine-dependent schizophrenics and nonpsychiatric controls. Neuropsychopharmacology. 2005 Mar;30(3):640-8.
Sanchez-Johnsen LA, Fitzgibbon ML, Ahluwalia JS, Spring BJ. Eating pathology among Black and White smokers. Eat Behav. 2005 Feb;6(2):127-36.
Holmes EW, Russell PM, Kinzler GJ, Reckard CR, Flanigan RC, Thompson KD, Bermes EW Jr. Oxidative tryptophan metabolism in renal allograft recipients: increased kynurenine synthesis is associated with inflammation and OKT3 therapy. Cytokine. 1992 May;4(3):205-13.
Cook JW, Spring B, McChargue DE, Borrelli B, Hitsman B, Niaura R, Keuthen NJ, Kristeller J. Influence of fluoxetine on positive and negative affect in a clinic-based smoking cessation trial. Psychopharmacology (Berl). 2004 Apr;173(1-2):153-9. Epub 2004 Jan 15.
Spring B, Pagoto S, McChargue D, Hedeker D, Werth J. Altered reward value of carbohydrate snacks for female smokers withdrawn from nicotine. Pharmacol Biochem Behav. 2003 Sep;76(2):351-60.
Spring B, Pingitore R, McChargue DE. Reward value of cigarette smoking for comparably heavy smoking schizophrenic, depressed, and nonpatient smokers. Am J Psychiatry. 2003 Feb;160(2):316-22.
Johnsen L, MacKirnan D, Spring B, Pingitore R, Sommerfeld BK. Smoking as subculture? Influence on Hispanic and non-Hispanic White women''''s attitudes toward smoking and obesity. Health Psychol. 2002 May;21(3):279-87.
Hitsman B, Spring B, Borrelli B, Niaura R, Papandonatos GD. Influence of antidepressant pharmacotherapy on behavioral treatment adherence and smoking cessation outcome in a combined treatment involving fluoxetine. Exp Clin Psychopharmacol. 2001 Nov;9(4):355-62.
Richmond M, Spring B, Sommerfeld BK, MeChargue D. Rumination and cigarette smoking: a bad combination for depressive outcomes? J Consult Clin Psychol. 2001 Oct;69(5):836-40.
Borrelli B, Spring B, Niaura R, Kristeller J, Ockene JK, Keuthen NJ. Weight suppression and weight rebound in ex-smokers treated with fluoxetine. J Consult Clin Psychol. 1999 Feb;67(1):124-31.
Record last reviewed: June 2005
Last Updated: June 30, 2005
Record first received: June 9, 2005
ClinicalTrials.gov Identifier: NCT00113737
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-07-05
Resources
- Fluoxetine (Cleveland Clinic)
- Fluoxetine (Drug Digest)

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