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Pravastatin |
Pravachol |
Pravastatin Systematic (IUPAC) name 3,5-dihydroxy-7- [6-hydroxy-2-methyl-8- (2-methylbutanoyloxy)- 1,2,6,7,8,8a- hexahydronaphthalen-1-yl]- heptanoic acid Identifiers CAS number 81093-37-0 ATC code C10AA03 PubChem 54687 DrugBank APRD00328 Chemical data Formula C23H36O7 Mol. weight 424.528 g/mol Pharmacokinetic data Bioavailability ? Protein binding 50% Metabolism ? Half life 77 hours Excretion ? Therapeutic considerations Pregna ...
Wikipedia - [full article]
Pravastatin Clinical Trials
- Effect of pravastatin on endothelial dysfunction following a single high fat meal
ClinicalTrials.gov Identifier: NCT00005117 - Active, not recruiting
Heart Diseases
- Rosuvastatin Versus Pravastatin in HIV Patients Treated with Boosted Protease Inhibitors (PI)
ClinicalTrials.gov Identifier: NCT00117494 - Active, not recruiting
Hyperlipidemia; HIV Infections
- Pravastatin, Idarubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00107523 - Active, not recruiting
adult acute myeloid leukemia
- Comparison of the Combination of Fenofibrate and Simvastatin Versus Pravastatin
ClinicalTrials.gov Identifier: NCT00362206 - Active, not recruiting
Hyperlipidemia
- Effects of Atorvastatin Versus Pravastatin on Platelet Inhibition by Clopidogrel
ClinicalTrials.gov Identifier: NCT00405717 - Recruiting
Ischemic Heart Disease; Acute Coronary Syndromes
- Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients with Abnormal Blood Lipids
ClinicalTrials.gov Identifier: NCT00006412 - Completed
HIV Infections; Lipodystrophy
- Prevention of Atherosclerosis and Heart Disease in Patients with Systemic Lupus Erythematosis (SLE)
ClinicalTrials.gov Identifier: NCT00054938 - Active, not recruiting
Systemic Lupus Erythematosus; Lupus
- Etoposide and Cisplatin or Carboplatin as First-Line Chemotherapy With or Without Pravastatin in Treating Patients With Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00433498 - Recruiting
Lung Cancer
- Yokohama Assessment of Fluvastatin, Pravastatin, Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Yokohama-ACS)
ClinicalTrials.gov Identifier: NCT00549926 - Recruiting
Coronary Disease; Hypercholesterolemia
- A Study to Evaluate Daily Pravastatin, Fenofibrate or Pravafen in the Treatment of Combined Hyperlipidemia
ClinicalTrials.gov Identifier: NCT00459745 - Recruiting
Combined Hyperlipidemia
- Single Dose Pravastatin Pharmacokinetics in Pediatric Peritoneal Dialysis Patients
ClinicalTrials.gov Identifier: NCT00571194 - Recruiting
Pediatrics Patients on Dialysis
- STOP CAP: Pravastatin and Atorvastatin to Prevent Heart Disease in People With High Cholesterol Level, Diabetes or Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00166036 - Recruiting
Diabetes Mellitus; Metabolic Syndrome X; Hypercholesterolemia
- Improving Symptoms of Schizophrenia and Schizoaffective Disorder by Supplementing Medications With Pravastatin
ClinicalTrials.gov Identifier: NCT00177580 - Recruiting
Schizophrenia; Schizoaffective Disorder
- Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
ClinicalTrials.gov Identifier: NCT00000542 - Active, not recruiting
Cardiovascular Diseases; Coronary Disease; Diabetes Mellitus; Heart Diseases; Hypercholesterolemia; Hypertension; Myocardial Infarction; ...
- Safety and Efficacy of Pravastatin in Relapsing-Remitting Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00200655 - Recruiting
Relapsing-Remitting Multiple Sclerosis
- Pravastatin or Atorvastatin Evaluation and Infection Therapy (TIMI22)
ClinicalTrials.gov Identifier: NCT00382460 - Completed
Actue Coronary Syndromes
- Pravastatin Efficacy and Safety Trial in Hypercholesterolemic Patients With Chronic Liver Disease
ClinicalTrials.gov Identifier: NCT00529178 - Completed
Hypercholesterolemia
- Study to Compare the Efficacy and Safety of Pitavastatin and Pravastatin in Elderly Patients
ClinicalTrials.gov Identifier: NCT00257686 - Completed
Hypercholesterolemia or Combined Dyslipidemia
- Pravastatin and Protease Inhibitors in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00221754 - Completed
HIV Infection; Hypercholesterolemia
- Efficacy and Safety of BMS-298585 Alone or in Combination With Pravastatin in Subjects With Mixed Dyslipidemia
ClinicalTrials.gov Identifier: NCT00245388 - Completed
Dyslipidemia
- This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.
ClinicalTrials.gov Identifier: NCT00380939 - Completed
Coronary Arteriosclerosis
- Pravastatin for Hyperlipidaemia in HIV.
ClinicalTrials.gov Identifier: NCT00227500 - Completed
HIV Infections; Lipid Metabolism; Glucose Metabolism; Metabolic Abnormality; Lipodystrophy; Cardiovascular Disease
- Endothelial Dysfunction as a Risk Factor in HIV Study
ClinicalTrials.gov Identifier: NCT00039663 - Completed
HIV Infections
- A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood
ClinicalTrials.gov Identifier: NCT00000941 - Completed
HIV Infections
- Influence of Pravastatin on Carotid Artery Structure and Function in HIV-Infected Patients Under Antiretroviral Therapy
ClinicalTrials.gov Identifier: NCT00147797 - Completed
HIV Infection; Carotid Atherosclerosis; Dyslipidemia
- The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs
ClinicalTrials.gov Identifier: NCT00017758 - Completed
HIV Infections; HIV Seronegativity; Lipodystrophy
- Prevention of Kidney Transplant Rejection
ClinicalTrials.gov Identifier: NCT00005010 - Completed
End-Stage Renal Disease; Chronic Allograft Nephropathy
- Harvard Atherosclerosis Reversibility Project (HARP)
ClinicalTrials.gov Identifier: NCT00000461 - Completed
Cardiovascular Diseases; Coronary Disease; Heart Diseases; Myocardial Ischemia
- Arterial Disease Multifactorial Intervention Trial (ADMIT)
ClinicalTrials.gov Identifier: NCT00000539 - Completed
Arterial Occlusive Diseases; Cardiovascular Diseases; Heart Diseases; Vascular Diseases; Diabetes Mellitus
Resources
- Pravachol (Drug Digest)
- Pravastatin (Drug Digest)
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