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Clopidogrel |
Plavix |
Clopidogrel Systematic (IUPAC) name (+)-(S)-methyl 2-(2-chlorophenyl)- 2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate Identifiers CAS number 113665-84-2 ATC code B01AC04 PubChem 60606 DrugBank APRD00444 Chemical data Formula C16H16ClNO2S Mol. weight 321.82 Pharmacokinetic data Bioavailability >50% Metabolism hepatic Half life 7–8 hours (inactive metabolite) Excretion 50% renal 46% biliary Therapeutic considerations Pregnancy cat. B1(AU) B(U ...
Wikipedia - [full article]
Clopidogrel Clinical Trials
- Clopidogrel Reloading in Clopidogrel Resistant Patients With ACS
ClinicalTrials.gov Identifier: NCT00444132 - Completed
Clopidogrel Non-Responsiveness
- Resistance to Aspirin and/or Clopidogrel Among Patients With PAD.
ClinicalTrials.gov Identifier: NCT00262561 - Recruiting
Intermittent Claudication
- Mirror Trial - Follow-Up Management of Peripheral Arterial Intervention with Clopidogrel
ClinicalTrials.gov Identifier: NCT00163267 - Recruiting
Age above 18
- The inhibition of platelet antiaggregating activity of clopidogrel by atorvastatin detected by erythromycin breath test: a metabolic inhibition of hepatic cytochrome P450-3A
ClinicalTrials.gov Identifier: NCT00004564 - Recruiting
Hypercholesterolemia; Thrombosis
- Effect of Clopidogrel Loading and Risk of PCI
ClinicalTrials.gov Identifier: NCT00457236 - Active, not recruiting
Coronary Artery Disease; Drug Resistance
- H2 Haplotype and CYP3As Polymorphisms and the Antiplatelet Response to Clopidogrel
ClinicalTrials.gov Identifier: NCT00433784 - Active, not recruiting
Coronary Artery Disease; Elective Percutaneous Coronary Intervention
- Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA)
ClinicalTrials.gov Identifier: NCT00050817 - Completed
Arteriosclerosis
- Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE)
ClinicalTrials.gov Identifier: NCT00249795 - Active, not recruiting
Atrial Fibrillation; Cardiovascular Disease
- Association of Clopidogrel Therapy and Stent Thrombosis
ClinicalTrials.gov Identifier: NCT00484926 - Recruiting
Coronary Artery Disease
- Clopidogrel and Aspirin Together: The Effect on C-Reactive Protein Trial
ClinicalTrials.gov Identifier: NCT00343876 - Recruiting
Coronary Artery Disease
- Influence Of Omeprazole On The Anti-Platelet Action Of Clopidogrel
ClinicalTrials.gov Identifier: NCT00349661 - Recruiting
Coronary Heart Disease
- PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes
ClinicalTrials.gov Identifier: NCT00153062 - Active, not recruiting
Cerebrovascular Accident
- Randomized Controlled Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial)
ClinicalTrials.gov Identifier: NCT00228423 - Recruiting
Saphenous Vein Graft Disease; Intimal Hyperplasia; Coronary Artery Bypass Graft Surgery
- Safety and Efficacy of Clopidogrel for Cerebral Infarction Treatment
ClinicalTrials.gov Identifier: NCT00386191 - Active, not recruiting
Cerebral Infarction
- Aspirin Non-Responsiveness and Clopidogrel Endpoint Trial.
ClinicalTrials.gov Identifier: NCT00222261 - Recruiting
Coronary Heart Disease; Angina Pectoris; Atherosclerosis
- 75 or 150 Mg Clopidogrel Maintenance Doses Following PCI
ClinicalTrials.gov Identifier: NCT00140465 - Completed
Coronary Disease
- Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE)
ClinicalTrials.gov Identifier: NCT00249873 - Active, not recruiting
Atrial Fibrillation; Vascular Risk
- Different Regimen of Aprotinine(Trasylol) Administration in Patients Receiving Antiplatelet Therapy With Clopidogrel (Plavix)
ClinicalTrials.gov Identifier: NCT00257751 - Recruiting
Coronary Artery Disease
- Effects of Atorvastatin Versus Pravastatin on Platelet Inhibition by Clopidogrel
ClinicalTrials.gov Identifier: NCT00405717 - Recruiting
Ischemic Heart Disease; Acute Coronary Syndromes
- A Study of the Onset and Offset of Antiplatelet Effects Comparing AZD6140, Clopidogrel, and Placebo With Aspirin
ClinicalTrials.gov Identifier: NCT00528411 - Recruiting
Coronary Artery Disease
- The Effects of Physical Training, ASA and Clopidogrel on the Walking Capacity of Patients With Stage II PAD
ClinicalTrials.gov Identifier: NCT00189618 - Recruiting
Peripheral Vascular Disease
- Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation (CLARINET)
ClinicalTrials.gov Identifier: NCT00396877 - Recruiting
Heart Defects, Congenital
- Biological Efficacy of Clopidogrel After Implantation of Drug-Eluting Stents (SPACE)
ClinicalTrials.gov Identifier: NCT00298428 - Recruiting
Coronary Artery Disease; Atherosclerosis; Diabetes Mellitus; Metabolic Syndrome X
- Influence of CYP2C19 Genetic Variants on Clopidogrel in Healthy Subjects
ClinicalTrials.gov Identifier: NCT00413608 - Recruiting
Healthy
- Platelets Induced Vasodilation, in Vitro and in Vivo Study
ClinicalTrials.gov Identifier: NCT00152646 - Recruiting
arteriopathy
- Evaluation and Comparison of Several Point-of-Care Platelet Function Tests in Predicting Clinical Outcomes in Clopidogrel Pre-Treated Patients Undergoing Elective PCI.
ClinicalTrials.gov Identifier: NCT00352014 - Recruiting
Stable Angina Pectoris
- CIPAMI-Study: Clopidogrel Administered Prehospital to Improve Primary PCI in Patients With Acute Myocardial Infarction
ClinicalTrials.gov Identifier: NCT00372216 - Recruiting
Myocardial Infarction
- Vascular Access Clinical Trials Data Coordinating Center
ClinicalTrials.gov Identifier: NCT00067119 - Recruiting
Kidney Failure
- Secondary Prevention of Small Subcortical Strokes (SPS3) Trial
ClinicalTrials.gov Identifier: NCT00059306 - Recruiting
Cerebrovascular Accident; Hypertension
- A Study to Evaluate the Discontinuation Effect of Clopidogrel After Drug Eluting Stent Implantation in Non-Diabetic Patients
ClinicalTrials.gov Identifier: NCT00493779 - Recruiting
Non-Diabetic Subjects With One or More Sirolimus or Paclitaxel Drug-Eluting Stents
- Value of Abciximab in Patients with AMI Undergoing PCI After Clopidogrel Pretreatment.
ClinicalTrials.gov Identifier: NCT00133250 - Recruiting
Myocardial Infarction
- Thromboelastography As A Tool for Possible Clopidogrel Resistance in The Patients Treated With Primary PCI for STEMI
ClinicalTrials.gov Identifier: NCT00517478 - Not yet recruiting
Myocardial Infarction; Cardiovascular Disease
- A Study of Aspirin and Clopidogrel in Patients with Idiopathic Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00105209 - Completed
Hypertension, Pulmonary
- Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II
ClinicalTrials.gov Identifier: NCT00130039 - Recruiting
Cerebral Infarction; Atherosclerosis
- A Comparison of AZD6140 and Clopidogrel in Patients With Acute Coronary Syndrome
ClinicalTrials.gov Identifier: NCT00391872 - Recruiting
Acute Coronary Syndrome
- Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00152724 - Recruiting
Healthy volunteers
- Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)
ClinicalTrials.gov Identifier: NCT00557921 - Not yet recruiting
Acute Coronary Syndrome; Myocardial Infarction; Coronary Artery Disease; Percutaneous Coronary Intervention
- Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)
ClinicalTrials.gov Identifier: NCT00115375 - Completed
Congenital Heart Defects; Blood Platelet Disorders
- Clopidogrel Only Before Percutaneous Coronary Intervention or Before Every Coronarography?
ClinicalTrials.gov Identifier: NCT00432120 - Completed
Ischemic Heart Disease
- Are Aspirin, Warfarin, and Clopidogrel Equally Effective in the Treatment of Patients With Symptomatic CHF and Reduced Ejection Fraction?
ClinicalTrials.gov Identifier: NCT00007683 - Completed
NYHA Class II, III or IV CHF; Left ventricular ejection fraction less than or equal to 35%
- Effect of Fluvastatin on Top of Clopidogrel and Aspirin in Patients After DES Implantation on Platelet Aggregation
ClinicalTrials.gov Identifier: NCT00465322 - Completed
Drug-Interactions
- Efficacy of Adjusted Clopidogrel Dose in Patients With Insufficient Platelet Inhibition
ClinicalTrials.gov Identifier: NCT00302913 - Completed
Coronary Artery Disease; Drug Resistance
- CASPAR : Clopidogrel and Acetyl Salicylic Acid in Bypass Surgery for Peripheral ARterial Disease
ClinicalTrials.gov Identifier: NCT00174759 - Completed
Arterial Occlusive Diseases
- ALBION "Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis"
ClinicalTrials.gov Identifier: NCT00360386 - Completed
Ischemia
- PROCLAIM: Study Examining Effects of Clopidogrel Compared to Placebo on Inflammation in Subjects With Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00296803 - Completed
Metabolic Syndrome X
- Efficacy and Safety of Adding Clopidogrel to Aspirin or Use of Metoprolol in Myocardial Infarction
ClinicalTrials.gov Identifier: NCT00222573 - Completed
Acute Myocardial Infarction
- A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects who are to undergo Percutaneous Coronary Intervention
ClinicalTrials.gov Identifier: NCT00097591 - Completed
Coronary Arteriosclerosis
- Which Therapy for Acute Heart Attacks?
ClinicalTrials.gov Identifier: NCT00121446 - Completed
Myocardial Infarction
- The Effect on Blood Cells, Known as Platelets, Using Prasugrel vs Clopidogrel in Patients With the Heart Problem Acute Coronary Syndrome
ClinicalTrials.gov Identifier: NCT00385944 - Completed
Acute Coronary Syndrome
- Clopidogrel Maintaining Dosage in Acute Coronary Syndrome After Drug Eluting Stent Implantation
ClinicalTrials.gov Identifier: NCT00404053 - Completed
Acute Coronary Syndrome
- Effect of Prasugrel on Platelets After One Week in Patients Already Taking Clopidogrel After a Cardiac Event
ClinicalTrials.gov Identifier: NCT00356135 - Suspended
Coronary Arteriosclerosis; Acute Coronary Syndrome
- A Trial of CS-747 Compared with Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention (PCI)
ClinicalTrials.gov Identifier: NCT00059215 - Completed
Cardiovascular Diseases; Heart Diseases
- Abciximab, Clopidogrel and PCI in ACS
ClinicalTrials.gov Identifier: NCT00133003 - Completed
Coronary Disease; Angina, Unstable
- Fast Assessment of Stroke and Transient ischemic attack to prevent Early Recurrence (FASTER)
ClinicalTrials.gov Identifier: NCT00109382 - Completed
Transient Ischemic Attack; Stroke
- Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE)
ClinicalTrials.gov Identifier: NCT00243178 - Terminated
Atrial Fibrillation; Vascular Risk
Resources
- Clopidogrel (Drug Digest)
- Clopidogrel (Cleveland Clinic)
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