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Effect of KW-3902IV in Combination with IV Furosemide on Renal Function in Subjects with CHF and Renal Impairment - Article


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Furosemide

Lasix 



Clinical Trial: Effect of KW-3902IV in Combination with IV Furosemide on Renal Function in Subjects with CHF and Renal Impairment

This study is currently recruiting patients.
Verified by NovaCardia September 2005

Sponsored by: NovaCardia
Information provided by: NovaCardia
ClinicalTrials.gov Identifier: NCT00159614

Purpose

The purpose of this study is to characterize the safety and tolerability of KW-3902IV and measure its effect on renal function.
Condition Intervention Phase
Heart Failure, Congestive
Renal Insufficiency
  Drug: KW-3902IV
 Phase II

MedlinePlus related topics:  Heart Failure;   Kidney Failure

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Safety Study

Official Title: Effect of KW-3902IV in Combination with IV Furosemide on Renal Function in Subjects with Congestive Heart Failure (CHF) and Renal Impairment

Further Study Details: 
Primary Outcomes: Comparison of KW-3902IV alone or with loop diuretic on renal function.
Expected Total Enrollment:  30

Study start: September 2005

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Stable congestive heart failure
  • Impaired renal function
  • Taking oral loop diuretic

Exclusion Criteria:

  • Acutely decompensated (unstable) and end stage heart failure
  • Diuretics other than loop diuretics
  • Pregnant or nursing
  • Inability to follow instructions
  • Participation in another clinical trial within past 30 days

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00159614

H C Dittrich, MD      858.523.4505    hcd@novacardia.com

California
      San Diego,  California,  United States; Not yet recruiting

Maryland
      Baltimore,  Maryland,  United States; Not yet recruiting

Massachusetts
      Boston,  Massachusetts,  United States; Not yet recruiting

      Ayer,  Massachusetts,  United States; Recruiting

Michigan
      Kalamazoo,  Michigan,  United States; Recruiting

Tennessee
      Tullahoma,  Tennessee,  United States; Recruiting

More Information

Study ID Numbers:  CKI-203
Last Updated:  September 11, 2005
Record first received:  September 7, 2005
ClinicalTrials.gov Identifier:  NCT00159614
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-09-13


Source: ClinicalTrials.gov
Cache Date: September 14, 2005

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Page Updated: October 3, 2005
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