Raloxifene |
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Raloxifene Systematic (IUPAC) name [6-hydroxy-2-(4-hydroxyphenyl)- benzothiophen-3-yl]- [4-[2-(1-piperidyl)ethoxy]phenyl] -methanone Identifiers CAS number 84449-90-1 ATC code G03XC01 PubChem 5035 DrugBank APRD00400 Chemical data Formula C28H27NO4S Mol. weight 473.584 g/mol Pharmacokinetic data Bioavailability ? Protein binding 95% Metabolism ? Half life 27.7 Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status ...
Wikipedia - [full article]
Raloxifene Clinical Trials
- Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer
ClinicalTrials.gov Identifier: NCT00003906 - Active, not recruiting
Breast Cancer
- Exemestane and Raloxifene in Treating Postmenopausal Women With a History of Ductal Carcinoma in Situ, Stage I, Stage II, or Stage III Breast Cancer
ClinicalTrials.gov Identifier: NCT00004247 - Active, not recruiting
Breast Cancer; breast cancer in situ
- Study Comparing Arzoxifene With Raloxifene in Women After Menopause With Osteoporosis
ClinicalTrials.gov Identifier: NCT00383422 - Active, not recruiting
Postmenopausal Osteoporosis
- Study Evaluating TSE-424/Placebo/Raloxifene in Preventing Osteoporosis in Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00481169 - Active, not recruiting
Osteoporosis
- AFTER: Altering Fat Through Estrogen and Raloxifene
ClinicalTrials.gov Identifier: NCT00149604 - Completed
Postmenopause
- Raloxifene With or Without Exercise Compared With Exercise Alone in Women Who Have Been Previously Treated for Breast Cancer
ClinicalTrials.gov Identifier: NCT00031811 - Active, not recruiting
Osteoporosis; stage I breast cancer; stage IIIB breast cancer; menopausal symptoms; stage IIIA breast cancer; stage II breast cancer; Quality of Life
- Combined Estrogen Blockade of the Breast With Exemestane and Raloxifene in Postmenopausal Women With a History of Breast Cancer Who Have No Clinical Evidence of Disease
ClinicalTrials.gov Identifier: NCT00200174 - Active, not recruiting
Breast Cancer
- Raloxifene for Prevention of Bone Loss in Postmenopausal Patients Receiving Chronic Corticosteroid Therapy
ClinicalTrials.gov Identifier: NCT00371956 - Recruiting
Osteoporosis
- Effects of Zoledronic Acid and Raloxifene on Bone Turnover Markers in Postmenopausal Women With Low Bone Mineral Density
ClinicalTrials.gov Identifier: NCT00431444 - Recruiting
Osteoporosis
- Cognitive and Neurophysiological Effects of Raloxifene in Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00065767 - Completed
Alzheimer Disease
- The Safety and Effectiveness of Surgery with or without Raloxifene for the Treatment of Pelvic Pain Caused by Endometriosis
ClinicalTrials.gov Identifier: NCT00001848 - Completed
Endometriosis; Pelvic Pain
- Raloxifene and Rimostil for Perimenopause-Related Depression
ClinicalTrials.gov Identifier: NCT00030147 - Recruiting
Climacteric Depression
- Raloxifene for Women With Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00368459 - Recruiting
Alzheimer's Disease
- Raloxifene and Goserelin in Preventing Breast Cancer in Women With a Family History of Breast Cancer
ClinicalTrials.gov Identifier: NCT00031850 - Completed
Breast Cancer
- A Phase II Trial of Raloxifene in Pre-Menopausal Women at High Risk for Developing Invasive Breast Cancer
ClinicalTrials.gov Identifier: NCT00001700 - Completed
Breast Cancer; Breast Neoplasm
- Induction of Ovulation With Raloxifene or Clomiphene Citrate in Polycystic Ovarian Syndrome
ClinicalTrials.gov Identifier: NCT00427700 - Not yet recruiting
Polycystic Ovary Syndrome
- Sequential Use of Study Drug and Raloxifene HCI in the Treatment of Postmenopausal Women with Osteoporosis
ClinicalTrials.gov Identifier: NCT00035256 - Completed
Osteoporosis, Postmenopausal
- Raloxifene Use for The Heart
ClinicalTrials.gov Identifier: NCT00190593 - Completed
Cardiovascular Diseases; Breast Neoplasms
- Phase II Study of Raloxifene in Patients With Recurrent Endometrial Cancer
ClinicalTrials.gov Identifier: NCT00004915 - Completed
recurrent endometrial cancer
- Long Term Effects of Raloxifene Treatment on Bone Quality
ClinicalTrials.gov Identifier: NCT00532428 - Completed
Osteoporosis, Post-Menopausal
- Comparison of Tibolone and Raloxifene on Bone Mineral Density in Osteopenic Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00431431 - Completed
Osteoporosis; Osteopenia
- Carotid Artery Intima-Media Thickness Following Exposure to Raloxifene or Placebo
ClinicalTrials.gov Identifier: NCT00532246 - Completed
Osteoporosis, Post-Menopausal
- CORAL: Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss
ClinicalTrials.gov Identifier: NCT00163137 - Completed
Osteoporosis
- Study of Hot Flashes and Night Sweats in Postmenopausal Women Receiving Combination Raloxifene and Oral Estrogen
ClinicalTrials.gov Identifier: NCT00332553 - Completed
Vasomotor Symptoms; Endometrial Safety
- Effect of Bazedoxifene, Raloxifene, and Placebo on Breast Density
ClinicalTrials.gov Identifier: NCT00418236 - Completed
Breast Cancer
- Estrogen Alternatives Study
ClinicalTrials.gov Identifier: NCT00108238 - Completed
Healthy
- EVA: Evista Alendronate Comparison
ClinicalTrials.gov Identifier: NCT00035971 - Completed
Osteoporosis
- Effects of Raloxifene on Hormone Levels
ClinicalTrials.gov Identifier: NCT00026962 - Completed
Breast Cancer
- A Comparison Study With Alendronate and Raloxifene in Postmenopausal Women With Osteoporosis
ClinicalTrials.gov Identifier: NCT00389740 - Completed
Osteoporosis, Postmenopausal
- Raloxifene in Preventing Breast Cancer in Premenopausal Women
ClinicalTrials.gov Identifier: NCT00019500 - Completed
Breast Cancer
- Effects of Teriparatide in Postmenopausal Women with Osteoporosis Previously Treated with Alendronate or Raloxifene
ClinicalTrials.gov Identifier: NCT00079924 - Completed
Postmenopausal Osteoporosis
- 2-Year Therapy With Teriparatide vs 1-yr Therapy Followed by 1-Year of Raloxifene or Calcium/Vit D in Severe Postmenopausal Osteoporosis
ClinicalTrials.gov Identifier: NCT00191425 - Completed
Osteoporosis, Postmenopausal
- Effects of Raloxifene on the Uterus and Ovaries of Premenopausal Patients
ClinicalTrials.gov Identifier: NCT00001837 - Completed
Breast Cancer; Breast Neoplasm
Resources
- Evista (Drug Digest)
- Raloxifene (Drug Digest)

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