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Phenytoin |
Dilantin; Dilantin Kapseals; Phenytek |
Phenytoin Systematic (IUPAC) name 5,5-diphenylimidazolidine-2,4-dione Identifiers CAS number 57-41-0 ATC code N03AB02 N03AB04, N03AB05 PubChem 1775 DrugBank APRD00241 Chemical data Formula C15H12N2O2 Mol. weight 252.268 g/mol Pharmacokinetic data Bioavailability 70-100% oral, 24.4% for rectal and intravenous administration Metabolism hepatic Half life 22 hours Excretion Primarily through the bile Therapeutic considerations Pregnancy cat. D Legal s ...
Wikipedia - [full article]
Phenytoin Clinical Trials
- Phenytoin as an Augmentation for SSRI Failures
ClinicalTrials.gov Identifier: NCT00146237 - Recruiting
Depression
- Patient, Provider, and Healthcare System Factors Associated with in Suboptimal Prescribing for Older Patients with Epilepsy
ClinicalTrials.gov Identifier: NCT00144001 - Active, not recruiting
Epilepsy
- Phenytoin and Driving Safety
ClinicalTrials.gov Identifier: NCT00581893 - Recruiting
Cognitive Measures; Driving Simulator Performance
- Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy
ClinicalTrials.gov Identifier: NCT00021866 - Active, not recruiting
Epilepsy; Seizure; Cognition Disorders
- Randomized Study of Albendazole in Patients with Epilepsy Due to Neurocysticercosis
ClinicalTrials.gov Identifier: NCT00004403 - Active, not recruiting
Epilepsy; Cysticercosis
- Evaluation of CYP2C9 Activity
ClinicalTrials.gov Identifier: NCT00162461 - Recruiting
Healthy volunteers
- Effects of Phenytoin on Cocaine Use in Humans - 2
ClinicalTrials.gov Identifier: NCT00000285 - Completed
Cocaine-Related Disorders
- Warfarin Metabolism and CYP2C9
ClinicalTrials.gov Identifier: NCT00162474 - Recruiting
Healthy Voluteers
- Effect of Ginkgo Biloba on Phenytoin Elimination
ClinicalTrials.gov Identifier: NCT00011063 - Completed
Healthy
- An Open-Label Interaction Study to Look at the Effects of Brivaracetam on Phenytoin When Taken Together in 15 Adult Patients With Epilepsy.
ClinicalTrials.gov Identifier: NCT00426673 - Completed
Epilepsy
- A Comparison of the Effectiveness and Safety of Topiramate and Phenytoin in Patients With New Onset Epilepsy Requiring Rapid Initiation of Antiepileptic Drug Treatment
ClinicalTrials.gov Identifier: NCT00210782 - Completed
Epilepsy
- Study of Efficacy of Phenytoin in Therapy of Patients With Bronchial Asthma
ClinicalTrials.gov Identifier: NCT00327028 - Completed
Bronchial Asthma
- Study of Efficacy of Phenytoin in Therapy of Children With Bronchial Asthma
ClinicalTrials.gov Identifier: NCT00366067 - Completed
Bronchial Asthma
- Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures
ClinicalTrials.gov Identifier: NCT00004817 - Completed
Post-Traumatic Seizure Disorder; Head Injuries
Resources
- Dilantin (Drug Digest)
- Dilantin Kapseals (Drug Digest)
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