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Tolterodine |
Detrol; Detrol LA; tolterodine tartrate |
Tolterodine Systematic (IUPAC) name 2-[3-[bis(1-methylethyl)amino]- 1-phenyl-propyl]-4-methyl-phenol Identifiers CAS number 124937-51-5 ATC code G04BD07 PubChem 60774 DrugBank APRD00146 Chemical data Formula C22H31NO Mol. weight 325.488 g/mol Pharmacokinetic data Bioavailability ? Protein binding Approximately 96.3%. Metabolism ? Half life 1.9-3.7 hours Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status ...
Wikipedia - [full article]
Tolterodine Clinical Trials
- Evaluate Efficacy and Safety of Tolterodine Extended Release Capsule Compared with Tolterodine Immediate Release Tablet in Patients with Symptoms of Overactive Bladder
ClinicalTrials.gov Identifier: NCT00139724 - Completed
Overactive bladder
- A Double-Blind, Paralleled Study Comparing Efficacy/Safety of Solifenacin to Tolterodine in Overactive Bladder Patients
ClinicalTrials.gov Identifier: NCT00368706 - Active, not recruiting
Overactive Bladder
- A Comparison of Tolterodine and Placebo Treatments on Nocturnal Frequency and Sleep Quality in Women After Menopause.
ClinicalTrials.gov Identifier: NCT00323635 - Recruiting
Urinary Incontinence
- A Study to Measure the Effect of Tolterodine ER on the Thickness of the Bladder Wall in Patients with Overactive Bladder
ClinicalTrials.gov Identifier: NCT00137397 - Completed
Urinary Incontinence
- Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder
ClinicalTrials.gov Identifier: NCT00444925 - Recruiting
Overactive Bladder
- Behavior Enhances Drug Reduction of Incontinence (BE-DRI)
ClinicalTrials.gov Identifier: NCT00090584 - Completed
Urinary Incontinence
- Effects of Tolterodine, a Non-Specific Muscarinic Antagonist, on Gastrointestinal Transit in Healthy Subjects
ClinicalTrials.gov Identifier: NCT00332137 - Completed
Health
- Efficacy and Tolerability of DITROPAN® XL (Oxybutynin Chloride) Versus DETROL® LA (Tolterodine Tartrate) in Treatment of Overactive Bladder
ClinicalTrials.gov Identifier: NCT00293839 - Completed
Urinary Incontinence
- Pharmacologic Effects of Darifenacin and Tolterodine on Cardiovascular Parameters in Healthy Subjects
ClinicalTrials.gov Identifier: NCT00413790 - Completed
Healthy
- Determine The Effectiveness Of Detrusitol In Patients Diagnosed With OAB.
ClinicalTrials.gov Identifier: NCT00143377 - Completed
Urinary Incontinence
- A Study of Solifenacin Succinate Compared to Tolterodine in Patients With Overactive Bladder
ClinicalTrials.gov Identifier: NCT00189800 - Completed
Overactive Bladder
- Effect of Detrol LA on Overactive Bladder Symptoms, Sexual Quality of Life and Sexual Function in Women
ClinicalTrials.gov Identifier: NCT00143481 - Completed
Urinary Incontinence
- Effect and Safety Of Detrol LA In Men With Overactive Bladder Symptoms With Or Without Bladder Outlet Obstruction
ClinicalTrials.gov Identifier: NCT00147654 - Completed
Urinary Incontinence
- ELB245 for 12 Weeks Versus 4mg Tolterodine in Patients With Incontinent Overactive Bladder (OAB)
ClinicalTrials.gov Identifier: NCT00439192 - Terminated
Overactive Bladder; Urinary Incontinence
Resources
- Detrol (Drug Digest)
- Detrol Consumer Information (U.S. Food and Drug Administration)
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