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Estradiol Transdermal System |
Alora; Climara; Esclim; Estraderm Patch; FemPatch; Menostar; Vivelle; Vivelle-Dot |
The estrogen patch is a delivery system for estradiol used as hormone replacement therapy to treat the symptoms of menopause, such as hot flashes and vaginal dryness, and to prevent osteoporosis. Originally marketed as Vivelle® (Novartis), it was discontinued in 2003 and reintroduced in a smaller form as Vivelle-Dot®. Although the estrogen is given transdermally rather than in the standard oral tablets, the estrogen patch carries similar risks and benefits as more conventional forms of est ...
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Estradiol Transdermal System Clinical Trials
- Treatment of Menstrual Migraine With Sequential, Transdermal, 17-Beta-Estradiol. A Double-Blind, Randomised, Cross-Over Trial.
ClinicalTrials.gov Identifier: NCT00204074 - Active, not recruiting
Migraine
- Smoking Cessation Treatment with Transdermal Nicotine Replacement Therapy - 1
ClinicalTrials.gov Identifier: NCT00067158 - Active, not recruiting
Tobacco Use Disorder
- An Open-Label Study to Evaluate Contraceptive Efficacy and Safety of the Transdermal Contraceptive System of Norelgestromine and Ethinyl Estradiol
ClinicalTrials.gov Identifier: NCT00307632 - Completed
Contraception
- Alzheimer's Disease: Therapeutic Potential of Estrogen
ClinicalTrials.gov Identifier: NCT00066157 - Active, not recruiting
Alzheimer Disease
- Transdermal Estradiol in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy and Chemotherapy
ClinicalTrials.gov Identifier: NCT00255632 - Recruiting
Prostate Cancer
- Phase II Trial of Transdermal Estradiol for Hormone Refractory Prostate Cancer
ClinicalTrials.gov Identifier: NCT00176644 - Recruiting
Prostate Cancer
- Smoking Cessation Treatment - 1
ClinicalTrials.gov Identifier: NCT00110825 - Active, not recruiting
Behavior Therapy; Bupropion; Tobacco Use Disorder; nicotine transdermal system
- Multi-Center Study to Evaluate Estradiol Transdermal Spray in the Treatment of Symptomatic Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00122200 - Completed
Postmenopause; Hot Flashes
- Smoking Cessation for Young Adults Who Binge Drink - 1
ClinicalTrials.gov Identifier: NCT00218452 - Recruiting
Adherence; Tobacco use cessation; alcohol & drug use; nicotine transdermal system
- Kronos Early Estrogen Prevention Study (KEEPS)
ClinicalTrials.gov Identifier: NCT00154180 - Recruiting
Menopause; Arteriosclerosis
- Methylphenidate Transdermal System (MTS) in the Treatment of Adult ADHD
ClinicalTrials.gov Identifier: NCT00506285 - Recruiting
Attention Deficit Hyperactivity Disorder
- Comparing Smoking Treatment Programs for Lighter Smokers - 1
ClinicalTrials.gov Identifier: NCT00086411 - Active, not recruiting
Tobacco Use Disorder
- Pharmacokinetics and Safety of Transdermal Megestrol Acetate
ClinicalTrials.gov Identifier: NCT00163072 - Recruiting
Cachexia
- Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Osteoarthritic Pain
ClinicalTrials.gov Identifier: NCT00345787 - Recruiting
Pain
- ELITE: Early versus Late Intervention Trial with Estradiol
ClinicalTrials.gov Identifier: NCT00114517 - Recruiting
Atherosclerosis
- Evaluate the Safety and Efficacy of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD
ClinicalTrials.gov Identifier: NCT00501293 - Recruiting
ADHD
- Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD
ClinicalTrials.gov Identifier: NCT00499863 - Recruiting
ADHD
- Trial to Evaluate the Efficacy of ThermoProfen (Matrix Transdermal Ketoprofen/CHADD™ System) in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee
ClinicalTrials.gov Identifier: NCT00488267 - Recruiting
Osteoarthritis
- Study to Assess the Efficacy and Safety of Transdermal Testosterone Patches in Menopausal Women with Low Libido.
ClinicalTrials.gov Identifier: NCT00131495 - Active, not recruiting
Hypoactive Sexual Desire Disorder
- POPART''MUS : Prevention of Post Partum Relapses with Progestin and Estradiol in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00127075 - Recruiting
Multiple Sclerosis
- Evaluation of Women's Experience With EVRA® (Norelgestromin + Ethinyl Estradiol) Transdermal Contraceptive Patch Compared With Previous Methods of Contraception.
ClinicalTrials.gov Identifier: NCT00261482 - Completed
Contraception; Female Contraception
- Selegiline Transdermal System for the Treatment of Cocaine Dependence - 1
ClinicalTrials.gov Identifier: NCT00032929 - Active, not recruiting
Cocaine-Related Disorders
- Baseline Sexual Function, Cognitive Function, Body Composition and Muscle Parameters and Pharmacokinetics of Transdermal Testosterone Gel in Women with Hypopituitarism
ClinicalTrials.gov Identifier: NCT00144404 - Recruiting
Panhypopituitarism
- Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Chronic, Moderate to Severe Non-Malignant Pain
ClinicalTrials.gov Identifier: NCT00126763 - Active, not recruiting
Pain
- Examining the Effectiveness of the Nicotine Patch in Male and Female Smokers - 2
ClinicalTrials.gov Identifier: NCT00135746 - Recruiting
Tobacco Use Disorder
- Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Low Back Pain
ClinicalTrials.gov Identifier: NCT00346047 - Recruiting
Low Back Pain
- A Study to Evaluate the Exposure of Norelgestromin and Ethinyl Estradiol From Commercial Lots of EVRA® (a Transdermal Contraceptive Patch Manufactured by LOHMANN Therapie-Systeme) and CILEST® (an Oral Contraceptive)
ClinicalTrials.gov Identifier: NCT00258063 - Completed
Contraception; Female Contraception
- Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Moderate to Severe Cancer Pain
ClinicalTrials.gov Identifier: NCT00126789 - Active, not recruiting
Pain; Cancer
- Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
ClinicalTrials.gov Identifier: NCT00080756 - Recruiting
Breast Cancer
- Transdermal Ketoprofen to Treat Mild to Moderate Osteoarthritis (OA) Pain of the Knee
ClinicalTrials.gov Identifier: NCT00108810 - Completed
Pain; Osteoarthritis, Knee
- Study of Transdermal Testosterone Patches in Surgically Menopausal Women With Low Libido
ClinicalTrials.gov Identifier: NCT00331123 - Active, not recruiting
Hypoactive Sexual Desire Disorder
- Study of Transdermal Testosterone Patches in Surgically Menopausal Women With Low Libido
ClinicalTrials.gov Identifier: NCT00331214 - Active, not recruiting
Hypoactive Sexual Desire Disorder
- Study of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido
ClinicalTrials.gov Identifier: NCT00338312 - Active, not recruiting
Hypoactive Sexual Desire Disorder
- A Study Evaluating the Safety, Effectiveness, and Pharmacokinetics of Transdermal Oxybutynin in Treating Overactive Bladder Associated With a Neurological Condition
ClinicalTrials.gov Identifier: NCT00224016 - Active, not recruiting
Detrusor Hyperreflexia
- Efficacy and Tolerability in Thai Women
ClinicalTrials.gov Identifier: NCT00185328 - Active, not recruiting
Menopause
- Endometrial Safety Study of Transdermal Testosterone (300 Mcg/Day) in Naturally Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00467259 - Active, not recruiting
Hypoactive Sexual Desire Disorder
- A Study of Efficacy and Safety With the Transdermal Contraceptive System Versus Mercilon.
ClinicalTrials.gov Identifier: NCT00236782 - Completed
Contraception
- Zoledronate and Estradiol in Preventing Bone Loss in Patients With Prostate Cancer
ClinicalTrials.gov Identifier: NCT00049491 - Recruiting
Osteoporosis; stage III prostate cancer; stage IV prostate cancer
- Postmarketing Study of ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) in Relation to Venous Thromboembolism (Blood Clots), Stroke and Heart Attacks.
ClinicalTrials.gov Identifier: NCT00331071 - Active, not recruiting
Female Contraception; Contraception
- Treatment of Hot Flushes in Asian Women With Ultra-Low Dose Estradiol Patch
ClinicalTrials.gov Identifier: NCT00185237 - Active, not recruiting
Hot Flushes in Menopause
- Estradiol Suppression for the Treatment of Metastatic Breast Cancer in Premenopausal Women
ClinicalTrials.gov Identifier: NCT00186121 - Active, not recruiting
Breast Cancer
- Transdermal Nicotine Patch to Reduce Nicotine Craving and Withdrawal in Schizophrenics
ClinicalTrials.gov Identifier: NCT00218218 - Active, not recruiting
Schizophrenia and Disorders With Psychotic Features; Tobacco Use Disorder; Schizophrenia
- Testosterone Therapy in Naturally Menopausal Women With Low Sexual Desire Receiving Transdermal Estrogen
ClinicalTrials.gov Identifier: NCT00384046 - Active, not recruiting
Hypoactive Sexual Desire Disorder
- The Effects of Continuous Administration of a Monophasic Oral Contraceptive (Norethindrone Acetate/Ethinyl Estradiol 1/20ug) on Bleeding Days and Endometrial and Ovarian Function
ClinicalTrials.gov Identifier: NCT00128726 - Active, not recruiting
menstrual cycle
- A 15-Day Study to Assess the Safety and Clinical Utility of Duragesic® (Fentanyl Transdermal Patch) in the Treatment of Children With Continuous Pain Requiring Narcotic Pain Relief Therapy
ClinicalTrials.gov Identifier: NCT00271414 - Active, not recruiting
Chronic Pain
- Transdermal Testosterone Gel/Effect on Erection Quality as Measured by DIR
ClinicalTrials.gov Identifier: NCT00425568 - Recruiting
Hypogonadism
- Study Comparing 17B Estradiol/TMG CC 1mg vs. Tibolone in Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00472004 - Recruiting
Vasomotor Symptoms
- A Study to Assess the Safety and Effectiveness of Durogesic® (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Long-Term Narcotic Pain Relief Therapy
ClinicalTrials.gov Identifier: NCT00271453 - Active, not recruiting
Chronic Pain
- Long-Term Extension of RECOVER- Long-Term Effect of the 24h Transdermal Delivery of Rotigotine in Subjects With Idiopathic Parkinson's Disease
ClinicalTrials.gov Identifier: NCT00519532 - Active, not recruiting
Parkinson Disease
- Trial to Assess PD Symptom Control to Four Doses of Rotigotine in a Transdermal Patch
ClinicalTrials.gov Identifier: NCT00522379 - Recruiting
Parkinson's Disease
- Phase I Study to Compare NP101(Sumatriptan Iontophoretic Transdermal Patch) With Three Formulations of Imitrex®
ClinicalTrials.gov Identifier: NCT00546650 - Recruiting
Healthy
- A Study of Efficacy and Safety With the Transdermal Contraceptive System.
ClinicalTrials.gov Identifier: NCT00236769 - Completed
Female Contraception; Contraception
- An Extension Trial to Investigate Long-Term Treatment With Transdermal Rotigotine in Idiopathic Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00263068 - Active, not recruiting
Restless Legs Syndrome
- Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
ClinicalTrials.gov Identifier: NCT00314652 - Completed
Osteoarthritis
- The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
ClinicalTrials.gov Identifier: NCT00315848 - Completed
Osteoarthritis
- A Study of Efficacy and Safety With the Transdermal Contraceptive System Versus Triphasil.
ClinicalTrials.gov Identifier: NCT00236795 - Completed
Female Contraception; Contraception
- Safety and Efficacy of Dose Conversion From Vicodin® to Buprenorphine Transdermal System in Subjects With Osteoarthritis
ClinicalTrials.gov Identifier: NCT00312572 - Completed
Osteoarthritis
- Trial of Zesteem (Estradiol) in Healing of Split Thickness Skin Graft Donor Sites.
ClinicalTrials.gov Identifier: NCT00426972 - Recruiting
Burn; Trauma; Varicose Ulcer
- Safety and Efficacy of the Buprenorphine Transdermal System in Subjects With Mod-to-Sev Osteoarthritis of Hip or Knee
ClinicalTrials.gov Identifier: NCT00313846 - Completed
Osteoarthritis
- Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Using Oral Contraceptive
ClinicalTrials.gov Identifier: NCT00377988 - Active, not recruiting
Female Contraception; Contraception
- Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS)
ClinicalTrials.gov Identifier: NCT00367822 - Active, not recruiting
Restless Legs Syndrome
- Safety of the Buprenorphine Transdermal Delivery System in Subjects With Mod-to-Sev Pain Following Orthopedic Surgery.
ClinicalTrials.gov Identifier: NCT00315835 - Completed
Postoperative Pain
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
ClinicalTrials.gov Identifier: NCT00003632 - Active, not recruiting
primary central nervous system lymphoma
- A Study to Assess the Safety, Dose Conversion, and Dose Individualization of Duragesic® (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Narcotic Pain Relief Therapy
ClinicalTrials.gov Identifier: NCT00271466 - Active, not recruiting
Chronic Pain
- Safety and Efficacy of Methylphenidate Transdermal System (MTS) Versus Concerta in Pediatric Patients (Aged 6-12 Years) With ADHD
ClinicalTrials.gov Identifier: NCT00444574 - Completed
Attention Deficit Hyperactivity Disorder
- Study of Physiological and High Dose Estradiol in the Treatment of Hormone Receptor Positive Metastatic Breast Cancer
ClinicalTrials.gov Identifier: NCT00324259 - Recruiting
Breast Neoplasms
- Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion
ClinicalTrials.gov Identifier: NCT00235547 - Recruiting
Abortion
- Hysteroscopy and Estradiol Trial
ClinicalTrials.gov Identifier: NCT00572819 - Not yet recruiting
Cervical Ripening
- Safety and Efficacy of a Contraceptive Vaginal Ring Delivering Nestorone® and Ethinyl Estradiol
ClinicalTrials.gov Identifier: NCT00263341 - Recruiting
Contraception
- An Open-Label Study to Compare the Bleeding Profile of Norelgestromin/Ethinyl Estradiol in an Extended Regimen to Norelgestromin/Ethinyl Estradiol Given in a Traditional Regimen
ClinicalTrials.gov Identifier: NCT00320580 - Completed
Metrorrhagia
- Safety/Efficacy Study of Drospirenone/Estradiol to Treat Postmenopausal Chinese Women With Vasomotor Symptoms.
ClinicalTrials.gov Identifier: NCT00356447 - Recruiting
Vasomotor Symptoms
- Clinical Use and Safety of the Fentanyl Transdermal Therapeutic System (TTS) in the Management of Pain in Patients With Cancer
ClinicalTrials.gov Identifier: NCT00269763 - Completed
Pain; Cancer
- Safety and Effectiveness of Buprenorphine Transdermal System in Elderly Subjects With Chronic Pain: Pilot Study.
ClinicalTrials.gov Identifier: NCT00313833 - Completed
Chronic Pain
- The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Low Back Pain.
ClinicalTrials.gov Identifier: NCT00315874 - Completed
Back Pain
- A Trial To Assess Switching From Ropinirole, Pramipexole Or Cabergoline To The Rotigotine Transdermal System In Idiopathic Parkinson's Disease
ClinicalTrials.gov Identifier: NCT00242008 - Completed
Parkinson's Disease
- Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer
ClinicalTrials.gov Identifier: NCT00459810 - Recruiting
Prostate Cancer
- Efficacy of the Fentanyl Transdermal Therapeutic System (TTS) in the Management of Pain in Patients With Cancer
ClinicalTrials.gov Identifier: NCT00269737 - Completed
Pain; Cancer
- Effects of Rotigotine Transdermal System in Subjects With Advanced-Stage Idiopathic Parkinson’s Disease
ClinicalTrials.gov Identifier: NCT00292227 - Completed
Parkinson’s Disease
- A Comparison of the Safety and Effectiveness of Two Forms of Patient-Controlled Pain Medication Used After Scheduled Abdominal or Pelvic Surgery: The Fentanyl Transdermal System Versus the Morphine Intravenous Pump
ClinicalTrials.gov Identifier: NCT00266539 - Completed
Pain, Postoperative
- Safety, Tolerability and Efficacy of the Transdermal System in Elderly Subjects With Major Depression
ClinicalTrials.gov Identifier: NCT00285766 - Completed
Major Depression
- The Safety and Efficacy of the Buprenorphine Transdermal System in Subjects With Chronic Back Pain.
ClinicalTrials.gov Identifier: NCT00315445 - Completed
Back Pain
- Clinical Estradiol Trial in Women With Schizophrenia
ClinicalTrials.gov Identifier: NCT00206570 - Recruiting
Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder
- CT-2103/Carboplatin vs Paclitaxel/Carboplatin for NSCLC in Women With Normal Estradiol
ClinicalTrials.gov Identifier: NCT00576225 - Recruiting
NSCLC
- Study to Compare the Effect of HRT on Breast and Cardiovascular Metabolic Markers in Postmenopausal Women.
ClinicalTrials.gov Identifier: NCT00145522 - Recruiting
Menopause
- A Comparison of the Safety and Effectiveness of Two Forms of Patient-Controlled Pain Medication Used After Total Hip Replacement: The E-TRANS Fentanyl Transdermal System Versus the Morphine Intravenous Pump
ClinicalTrials.gov Identifier: NCT00264485 - Completed
Analgesia; Pain, Postoperative
- Safety and Tolerability of Long-Term Treatment by Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00531609 - Recruiting
Alzheimer's Disease
- Efficacy and Safety of Rivastigmine Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00423085 - Recruiting
Alzheimer's Disease
- The Influence of Estradiol Supplementation During the Luteal in Patients Undergoing IVF Treatment
ClinicalTrials.gov Identifier: NCT00490308 - Not yet recruiting
Infertility
- Convenience, Tolerability, and Safety of Change in the Administration of Rivastigmine From Capsules to a Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00549601 - Recruiting
Alzheimer's Disease
- Immunotherapy Combined With Chemotherapy Followed by Radiation Therapy and Chemotherapy in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
ClinicalTrials.gov Identifier: NCT00059956 - Active, not recruiting
primary central nervous system lymphoma
- Study Evaluating the Bioequivalence of Levonorgestrel/Ethinyl Estradiol Combinations in Cycling Women
ClinicalTrials.gov Identifier: NCT00447863 - Not yet recruiting
Contraception
- Perfusion Magnetic Resonance Imaging in Measuring the Growth of Blood Vessels in Newly Diagnosed Brain Tumors
ClinicalTrials.gov Identifier: NCT00005790 - Active, not recruiting
genetic condition; Cancer; adult brain tumor; Brain Tumor; stage/type, adult brain tumor; body system/site cancer; central nervous system cancer; ...
- Eligibility Screening of Patients with Central Nervous System Tumors for the National Cancer Institute's (NCI) Clinical Research Protocols
ClinicalTrials.gov Identifier: NCT00035373 - Recruiting
Central Nervous System Neoplasms
- Study of an External Responsive Neurostimulator System on Epileptiform Activity
ClinicalTrials.gov Identifier: NCT00158067 - Active, not recruiting
Epilepsy
- Study Evaluating Levonorgestrel/Ethinyl Estradiol (LNG/EE) in PMS
ClinicalTrials.gov Identifier: NCT00161681 - Completed
Premenstrual Syndrome
- Chemotherapy, Filgrastim, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
ClinicalTrials.gov Identifier: NCT00003929 - Active, not recruiting
AIDS-related primary CNS lymphoma; primary central nervous system lymphoma
- Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors
ClinicalTrials.gov Identifier: NCT00002472 - Active, not recruiting
childhood central nervous system germ cell tumor; extragonadal germ cell tumor; adult central nervous system germ cell tumor; ...
- Targeted Interventions for Weight-Concerned Smokers
ClinicalTrials.gov Identifier: NCT00105482 - Recruiting
Nicotine Dependence
- Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Primary CNS Lymphoma
ClinicalTrials.gov Identifier: NCT00003061 - Active, not recruiting
primary central nervous system lymphoma
- L-Dihydroxyphenylserine (L-DOPS) for Norepinephrine Deficiency: Interactions With Carbidopa and Entacapone
ClinicalTrials.gov Identifier: NCT00547911 - Recruiting
Parkinson Disease; Multiple System Atrophy; Autonomic Nervous System Diseases
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