Not Signed In -
Celecoxib |
Celebrex |
Celecoxib Systematic (IUPAC) name 4-[5-(4-methylphenyl)-3-(trifluoromethyl) pyrazol-1-yl]benzenesulfonamide Identifiers CAS number 169590-42-5 ATC code L01XX33 M01AH01 PubChem 2662 DrugBank APRD00373 Chemical data Formula C17H14N3F3O2S Mol. weight 381.373 g/mol Pharmacokinetic data Bioavailability ? Protein binding 97% (mainly to albumin) Metabolism Hepatic (mainly CYP2C9) Half life ~11 hours Excretion Renal 27%, faecal 57% Therapeutic con ...
Wikipedia - [full article]
Resources
- Celebrex (Drug Digest)
- Celebrex Consumer Information (U.S. Food and Drug Administration)
Celecoxib News Headlines
- COX-2 drugs may raise risk of repeat heart attack
Reuters - Mon, 29 Jan 2007 05:13 EST
- Celebrex Approved To Treat Juvenile Rheumatoid Arthritis
MedicalNewsToday - Fri, 29 Dec 2006 08:00 EST
- Phase II Trial Of Continuous Low-Dose Oral Cyclophosphamide And Celecoxib For Metastatic Renal Cell Carcinoma
MedicalNewsToday - Wed, 22 Nov 2006 08:00 EST
- Unlocking Colon Cancer With Key Of Prevention
MedicalNewsToday - Fri, 01 Sep 2006 09:00 EST
- New Celebrex Study: Unlocking Colon Cancer With Key Of Prevention
ScienceDaily - Thu, 31 Aug 2006 03:00 EST
- Ultrasound good, drugs bad for knee injury
MSNBC - Fri, 14 Jul 2006 12:08 EST
- Ultrasound good, drugs bad for knee injury
Reuters - Thu, 13 Jul 2006 11:05 EST
- To Avoid Stomach Upset In Arthritis Patients, Drug Combination More Effective
MedicalNewsToday - Thu, 04 May 2006 12:00 EST
- Celecoxib Increases Risk Of Heart Attack, New Study Finds
MedicalNewsToday - Thu, 02 Mar 2006 11:00 EST
- Celecoxib May Help Prevent Colorectal Cancer In High Risk Patients, Studies Confirm
MedicalNewsToday - Mon, 03 Apr 2006 11:00 EST
- Celebrex ups heart disease risk, but could halt colon cancer
The Earth Times - Mon, 03 Apr 2006 05:06 EST
- Common painkillers may impair rotator cuff healing
Reuters - Thu, 30 Mar 2006 07:29 EST
- Short-term Celebrex seems safe for osteoarthritis
Reuters - Mon, 27 Feb 2006 05:12 EST
- ExCel Breast Cancer Prevention Study Back On Track
MedicalNewsToday - Sat, 04 Mar 2006 11:00 EST
- Regular Use Of Selective COX-2 Inhibitors Decreases Risk Of Breast Cancer
ScienceDaily - Mon, 30 Jan 2006 03:00 EST
- Combination of Lipitor® and Celecoxib at lower doses is most effective at limiting colon cancer development
MedicalNewsToday - Mon, 18 Apr 2005 06:00 EST
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