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Moxifloxacin |
Avelox; moxifloxacin hydrochloride |
Moxifloxacin Systematic (IUPAC) name 1-cyclopropyl-7-[(1S,6S)-2,8-diazabicyclo [4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo- quinoline-3-carboxylic acid Identifiers CAS number 354812-41-2 ATC code J01MA14 PubChem 152946 DrugBank APRD00281 Chemical data Formula C21H24N3FO4 Mol. weight 401.431 g/mol Pharmacokinetic data Bioavailability 86 to 92% Protein binding 30 to 50% Metabolism Glucuronide and sulfate conjugation Cytochrome P450 system not involved ...
Wikipedia - [full article]
Moxifloxacin Clinical Trials
- TBTC Study 28: Moxifloxacin Vs Isoniazid for TB Treatment
ClinicalTrials.gov Identifier: NCT00144417 - Active, not recruiting
Tuberculosis
- Moxifloxacin As Part of a Multi-Drug Regimen For Tuberculosis
ClinicalTrials.gov Identifier: NCT00082173 - Active, not recruiting
Tuberculosis
- Moxifloxacin Prophylaxis: Moxifloxacin in the Prevention of Bacteremia After High-Dose Chemotherapy and Transplantation of Peripheral Stem Cells
ClinicalTrials.gov Identifier: NCT00398411 - Recruiting
Hodgkin Disease; Non-Hodgkin Lymphoma; Multiple Myeloma; Bacteremia
- TBTC Study 27/28 PK: Moxifloxacin Pharmacokinetics During TB Treatment
ClinicalTrials.gov Identifier: NCT00164463 - Active, not recruiting
Tuberculosis
- Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer
ClinicalTrials.gov Identifier: NCT00062231 - Active, not recruiting
adult solid tumor; fever, sweats, and hot flashes; hematopoietic and lymphoid cancer; Infection; Neutropenia
- Pharmacokinetic Issues of Moxifloxacin Plus Rifapentine
ClinicalTrials.gov Identifier: NCT00460759 - Recruiting
Mycobacterium Tuberculosis
- TBTC Study 27: Moxifloxacin Vs Ethambutol for TB Treatment
ClinicalTrials.gov Identifier: NCT00140309 - Completed
Tuberculosis, Pulmonary
- Pharmacokinetic Evaluation of Moxifloxacin IV to Enteral Switch Therapy in Intensive Care Patients
ClinicalTrials.gov Identifier: NCT00458900 - Recruiting
Pneumonia
- A Safety Evaluation of ECG Intervals and Blood Pressure in Normal Healthy Volunteers After Use of Nebivolol, Atenolol, Moxifloxacin, or Placebo
ClinicalTrials.gov Identifier: NCT00158093 - Completed
Hypertension
- A Study to Compare the Effect on Heart Rhythm of 3 Days of GSK189075, Placebo, or Moxifloxacin in Healthy Adults
ClinicalTrials.gov Identifier: NCT00532610 - Recruiting
Type 2 Diabetes
- Plasma and Abscess Fluid Pharmacokinetics of Cefpirome and Moxifloxacin After Single and Multiple Dose Administration
ClinicalTrials.gov Identifier: NCT00280514 - Recruiting
Abscess or Abdominal Cyst
- Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department
ClinicalTrials.gov Identifier: NCT00323219 - Recruiting
Cellulitis
- Prospective Randomized Comparison of Zymar(Gatifloxacin) and Vigamox (Moxifloxacin) in Killing Conjunctival Bacterial Flora Following a One-Hour Application
ClinicalTrials.gov Identifier: NCT00466570 - Recruiting
Conjunctical Flora
- Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis
ClinicalTrials.gov Identifier: NCT00493038 - Recruiting
Sinusitis; Bacterial Infections
- Moxifloxacin vs. Polytrim for Conjunctivitis
ClinicalTrials.gov Identifier: NCT00581542 - Recruiting
Conjunctivitis
- Comparison of Moxifloxacin With Piperacillin/Tazobactam Followed by Amoxicillin/Clavulanic Acid in Patients With a Complicated Skin and Skin Structure Infection
ClinicalTrials.gov Identifier: NCT00402727 - Recruiting
Abscess; Wound Infection; Diabetic Foot; Infected Ischemic Ulcer; Soft Tissue Infections
- A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis
ClinicalTrials.gov Identifier: NCT00254566 - Recruiting
Bronchitis, Chronic
- A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease
ClinicalTrials.gov Identifier: NCT00453349 - Recruiting
Pelvic Inflammatory Disease
- Esomeprazole, Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori Infection
ClinicalTrials.gov Identifier: NCT00455806 - Recruiting
Helicobacter Pylori Infection; Chronic Gastritis
- Local Moxifloxacin and Povidone Iodine Versus Povidone Iodine Alone as a Prophylaxis Before Eye Operations
ClinicalTrials.gov Identifier: NCT00335088 - Recruiting
Eye Infections
- Therapy of Complicated Intra-Abdominal Infections With Moxifloxacin or Ertapenem
ClinicalTrials.gov Identifier: NCT00492726 - Recruiting
Intra-Abdominal Infections
- Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00534287 - Recruiting
Severe Sepsis; Septic Shock
- Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant
ClinicalTrials.gov Identifier: NCT00324324 - Recruiting
Brain and Central Nervous System Tumors; Breast Cancer; Chronic Myeloproliferative Disorders; Gestational Trophoblastic Tumor; Infection; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases; Ovarian Cancer; Testicular Germ Cell Tumor
- Comparison of the Effect of 4th Generation Fluoroquinolones, Gatifloxacin and Moxifloxacin, on Epithelial Healing Following Photorefractive Keratectomy (PRK), A Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personn
ClinicalTrials.gov Identifier: NCT00414011 - Completed
Epithelium, Corneal
- Intermittent Moxifloxacin Therapy For The Prevention Of Acute Exacerbations In Patients With Chronic Bronchitis
ClinicalTrials.gov Identifier: NCT00473460 - Completed
Pulmonary Disease; Acute Excacerbation of Chronic Bronchitis (AECB)
- Efficacy and Safety of Sequential IV/PO Moxifloxacin in Comparison to IV Levofloxacin Plus IV Ceftriaxone Followed by PO Levofloxacin, in the Treatment of Patients With Community-Acquired Pneumonia
ClinicalTrials.gov Identifier: NCT00431678 - Completed
Community-Acquired Pneumonia
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