Rosiglitazone |
Avandia |
Rosiglitazone Systematic (IUPAC) name 5-((4-(2-(methyl-2-pyridinylamino) ethoxy)phenyl)methyl)- 2,4-thiazolidinedione Identifiers CAS number 122320-73-4 ATC code A10BG02 PubChem 77999 DrugBank APRD00403 Chemical data Formula C18H19N3O3S Mol. weight 357.428 g/mol Pharmacokinetic data Bioavailability 99% Protein binding 99.8% Metabolism Hepatic (CYP2C8-mediated) Half life 3-4 hours Excretion Renal (64%) and fecal (23%) Therapeutic considerations ...
Wikipedia - [full article]
Resources
- Avandia (Drug Digest)
- Avandia Consumer Information (U.S. Food and Drug Administration)
Rosiglitazone News Headlines
- New oral drug for type 2 diabetes shows promise
Reuters - Thu, 15 Feb 2007 11:01 EST
- The Right Balance Drives The Field Of PPAR Agonist R&D
MedicalNewsToday - Sun, 14 Jan 2007 07:00 EST
- Landmark Study Shows Avandia(R) (rosiglitazone Maleate) Is More Effective Than Metformin Or A Sulfonylurea In Long-Term Blood Sugar Control
MedicalNewsToday - Tue, 05 Dec 2006 08:00 EST
- Effective Blood Glucose Control For Type 2 Diabetes Patients Shown By Landmark Study
MedicalNewsToday - Sat, 09 Dec 2006 01:00 EST
- Novel Oral Platelet Growth Factor, Eltrombopag, To Be Evaluated In Long Term ITP Study
MedicalNewsToday - Sun, 10 Dec 2006 08:00 EST
- Avandia(R) (rosiglitazone Maleate) Reduced Risk Of Progression From Pre-Diabetes To Type 2 Diabetes By 62 Percent
MedicalNewsToday - Sat, 16 Sep 2006 07:00 EST
- Drug Can Prevent Diabetes in Many at High Risk, Study Suggests
New York Times - Sun, 17 Sep 2006 04:00 EST
- Prevention By Drug Possible for Patients with High Risk Of Type 2 Diabetes
MedicalNewsToday - Tue, 19 Sep 2006 05:00 EST
- Diabetes Can Be Prevented With Drug Therapy, Study Shows
ScienceDaily - Fri, 15 Sep 2006 03:00 EST
- Avandia May Prevent Diabetes For High Risk People
MedicalNewsToday - Fri, 15 Sep 2006 05:00 EST
- FDA Approves Avandamet® (rosiglitazone Maleate And Metformin HCl) As Inital Therapy In The Treatment Of Type 2 Diabetes
MedicalNewsToday - Sun, 16 Jul 2006 06:00 EST
- GlaxoSmithKline Announces FDA Approval And The Launch Of Avandamet(R) (Rosiglitazone Maleate And Metformin HCl) In The Treatment Of Diabetes
MedicalNewsToday - Fri, 14 Jul 2006 06:00 EST
- Researchers Pinpoint Causes Of Adverse Reactions To Popular Type 2 Diabetes Drugs
ScienceDaily - Thu, 01 Jun 2006 02:00 EST
- Pinpointing Causes Of Adverse Reactions To Popular Type 2 Diabetes Drugs, Joslin Diabetes Center
MedicalNewsToday - Fri, 02 Jun 2006 07:00 EST
- Joslin Researchers Reveal Mechanisms Behind A Class Of Oral Agents Used To Treat Type 2 Diabetes
MedicalNewsToday - Mon, 13 Mar 2006 01:00 EST
- Rosiglitazone safe with some patients: study
Reuters - Tue, 12 Jul 2005 04:44 EST
- Avandia safe in diabetics with liver damage
Reuters - Tue, 12 Jul 2005 06:32 EST

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