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Spironolactone |
Aldactone |
Spironolactone Systematic (IUPAC) name ? Identifiers CAS number 52-01-7 ATC code C03DA01 PubChem 5833 DrugBank APRD01234 Chemical data Formula C24H32O4S Mol. weight 416.574 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life 10 minutes Excretion ? Therapeutic considerations Pregnancy cat. C (USA); B3 (Aus) Legal status Routes ? Spironolactone (marketed as Aldactone®, Novo-Spiroton®, Spiractin®, ...
Wikipedia - [full article]
Spironolactone Clinical Trials
- Safety and Efficacy of Larger Dose of Spironolactone for the Treatment of Patients with Nonischemic Cardiomyopathy
ClinicalTrials.gov Identifier: NCT00125437 - Recruiting
Heart Failure, Congestive
- Spironolactone Safety in Dialysis Patients
ClinicalTrials.gov Identifier: NCT00328809 - Recruiting
End Stage Renal Disease; Congestive Heart Failure
- Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcoholics
ClinicalTrials.gov Identifier: NCT00226109 - Recruiting
Cardiomyopathy, Alcoholic; Alcoholism
- Spironolactone in Patients With Single Ventricle Heart
ClinicalTrials.gov Identifier: NCT00211081 - Active, not recruiting
Single Ventricle
- Spironolactone to Decrease Potassium Wasting in Hypercalciurics on Thiazides Diuretics
ClinicalTrials.gov Identifier: NCT00276289 - Recruiting
Idiopathic Hypercalciuria; Hypokalemia Caused by Thiazide Diuretics
- Cardiovascular Protective Effect of Spironolactone in Hemodialysis
ClinicalTrials.gov Identifier: NCT00277693 - Recruiting
Hemodialysis
- PIE II: Pharmacological Intervention in the Elderly II
ClinicalTrials.gov Identifier: NCT00123955 - Active, not recruiting
Diastolic Heart Failure
- Autoregulation of Glomerular Filtration Rate in Patients With Type 1 Diabetes During Spironolactone Therapy
ClinicalTrials.gov Identifier: NCT00335413 - Not yet recruiting
Hypertension
- Addition of Spironolactone in Patients With Resistant Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00524615 - Not yet recruiting
Hypertension
- Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?
ClinicalTrials.gov Identifier: NCT00291720 - Recruiting
Chronic Kidney Disease; Cardiovascular Disease
- The Efficacy of Spironolactone in Patients With Resistant Hypertension
ClinicalTrials.gov Identifier: NCT00430794 - Not yet recruiting
Hypertension
- RAAS, Inflammation, and Post-Operative Atrial Fibrillation - Specific Aim 3
ClinicalTrials.gov Identifier: NCT00141778 - Recruiting
Atrial Fibrillation
- Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss
ClinicalTrials.gov Identifier: NCT00175617 - Recruiting
Female Pattern Hair Loss
- Using the Drug Spironolactone to test if it Reduces Protein Leakage from the Kidney
ClinicalTrials.gov Identifier: NCT00106561 - Completed
Kidney Disease; Diabetic Nephropathy; Glomerulonephritis; Proteinuria
- Aldosterone Antagonism in Diastolic Heart Failure
ClinicalTrials.gov Identifier: NCT00108251 - Recruiting
Congestive Heart Failure
- Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women with Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome
ClinicalTrials.gov Identifier: NCT00004311 - Completed
Acanthosis Nigricans; Polycystic Ovary Syndrome
- Left Ventricular Hypertrophy and Spironolactone in End Stage Renal Disease
ClinicalTrials.gov Identifier: NCT00548912 - Completed
Kidney Failure, Chronic
- Spironolactone Combined With Captopril and Carvedilol for the Treatment of Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00240656 - Completed
Hypertension, Pulmonary
- Spironolactone for Reducing Proteinuria in Diabetic Nephropathy
ClinicalTrials.gov Identifier: NCT00498537 - Completed
Diabetic Nephropathy
- Treatment of Boys with Precocious Puberty
ClinicalTrials.gov Identifier: NCT00001202 - Completed
Precocious Puberty
- Spironolactone in Diabetic Nephropathy
ClinicalTrials.gov Identifier: NCT00317954 - Completed
Diabetic Nephropathy
- Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients
ClinicalTrials.gov Identifier: NCT00188045 - Terminated
Alcoholic Cirrhosis
Resources
- Aldactone (Drug Digest)
- Spironolactone (Drug Digest)
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