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Acyclovir |
Zovirax |
Aciclovir Systematic (IUPAC) name 2-amino-9-(2-hydroxyethoxymethyl)- 3H-purin-6-one Identifiers CAS number 59277-89-3 ATC code J05AB01 D06BB03 S01AD03 PubChem 2022 DrugBank APRD00567 Chemical data Formula C8H11N5O3 Mol. weight 225.21 g/mol Pharmacokinetic data Bioavailability 10–20% (oral) Protein binding 9-33% Metabolism Viral thymidine kinase Half life 2.2–20 hours Excretion Renal Therapeutic considerations Pregnancy cat. B3 (Au), B (U. ...
Wikipedia - [full article]
Acyclovir Clinical Trials
- Oral acyclovir for neonatal HSV disease of the skin,eyes and mouth
ClinicalTrials.gov Identifier: NCT00031447 - Active, not recruiting
Herpes Simplex
- Assessment of oral acyclovir in neonates with HSV involving the CNS
ClinicalTrials.gov Identifier: NCT00031460 - Active, not recruiting
Herpes Simplex
- Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System
ClinicalTrials.gov Identifier: NCT00006132 - Recruiting
Herpes Simplex
- A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes
ClinicalTrials.gov Identifier: NCT00076232 - Recruiting
HIV Infections; HIV Seronegativity; Herpes Genitalis
- Iontophoretic Application of Acyclovir Gel to Treat Cold Sores
ClinicalTrials.gov Identifier: NCT00469300 - Active, not recruiting
Herpes Labialis
- Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel with Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects with Acquired Immunodeficiency Syndrome (AIDS)
ClinicalTrials.gov Identifier: NCT00002186 - Completed
Herpes Simplex; HIV Infections
- HSV-2 Shedding Resolution After Acyclovir Treatment
ClinicalTrials.gov Identifier: NCT00495573 - Recruiting
Genital Herpes
- Efficacy and Safety Study of ME-609 and Acyclovir for Treatment of Herpes Simplex Labialis
ClinicalTrials.gov Identifier: NCT00361881 - Active, not recruiting
Herpes Labialis
- Episodic Acyclovir Therapy for Genital Ulcers
ClinicalTrials.gov Identifier: NCT00164424 - Recruiting
HIV Infections; Ulcer; Herpes Simplex
- Usage of Acyclovir for Suppression of HIV-1 and HSV-2 Coinfected Persons in Cameroon
ClinicalTrials.gov Identifier: NCT00209313 - Active, not recruiting
HIV-1 and HSV-2 Coinfection; HIV Infections
- A Randomized Trial to Evaluate the Suppressive Effect of High-Dose Acyclovir Versus Valacyclovir on Persons With HSV-2
ClinicalTrials.gov Identifier: NCT00362297 - Recruiting
Genital Herpes
- A Comparison of 882C87 Versus Acyclovir in the Treatment of Herpes Zoster in Patients with Weakened Immune Systems
ClinicalTrials.gov Identifier: NCT00002315 - Completed
HIV Infections; Chickenpox
- Comparison of Brovavir Versus Acyclovir in the Treatment of Herpes in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00000953 - Completed
HIV Infections; Chickenpox
- A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3
ClinicalTrials.gov Identifier: NCT00000712 - Completed
HIV Infections
- Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation
ClinicalTrials.gov Identifier: NCT00045292 - Active, not recruiting
Cancer; Infection
- Effectiveness of Acyclovir in Suppressing HIV Viral Load in Women Coinfected With HIV and Herpes Simplex Virus Type 2 (HSV-2)
ClinicalTrials.gov Identifier: NCT00371592 - Recruiting
HIV Infections; Herpesvirus 2, Human
- Acyclovir to Treat Patients Co-Infected With HIV and Herpes Viruses in Uganda
ClinicalTrials.gov Identifier: NCT00405821 - Recruiting
HIV Infections; Herpes Genitalis
- The Safety and Effectiveness of Zidovudine Plus Acyclovir in Patients with Early HIV Infection
ClinicalTrials.gov Identifier: NCT00002290 - Completed
HIV Infections
- Phase III Randomized, Placebo-Controlled Study of Acyclovir Oral Suspension for Neonatal Herpes Simplex Virus Infection Limited to the Skin, Eyes, and Mouth
ClinicalTrials.gov Identifier: NCT00004757 - Completed
Herpes Simplex
- Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Limited to Skin, Eyes, and Mouth
ClinicalTrials.gov Identifier: NCT00006135 - Completed
Herpes Simplex
- Herpetic Eye Disease Study (HEDS) II
ClinicalTrials.gov Identifier: NCT00000139 - Active, not recruiting
Keratitis, Herpetic; Ocular Herpes Simplex; Herpes Simplex
- A Study of Zidovudine Plus Acyclovir in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001010 - Completed
HIV Infections
- Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection
ClinicalTrials.gov Identifier: NCT00004644 - Completed
Herpes Simplex
- Treatment and Suppression of Hairy Leukoplakia in ARC Patients With Oral Acyclovir (ACV)
ClinicalTrials.gov Identifier: NCT00002026 - Completed
Leukoplakia, Hairy; HIV Infections
- Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients with AIDS Who Have Not Had Success with Acyclovir
ClinicalTrials.gov Identifier: NCT00000985 - Completed
Herpes Simplex; HIV Infections
- Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS
ClinicalTrials.gov Identifier: NCT00000693 - Completed
Cytomegalovirus Retinitis; HIV Infections
- The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the Blood
ClinicalTrials.gov Identifier: NCT00001115 - Completed
Herpes Simplex; HIV Infections
- A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients
ClinicalTrials.gov Identifier: NCT00002000 - Completed
Herpes Simplex; HIV Infections
- Kidney Transplants in People with HIV Infection
ClinicalTrials.gov Identifier: NCT00023478 - Active, not recruiting
HIV Infections; End-Stage Renal Disease
- A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002084 - Completed
Herpes Simplex; HIV Infections
- A Randomized Controlled Trial of Acyclovir Among HIV and HSV-2 Co-Infected Women, Chiang Rai, Thailand
ClinicalTrials.gov Identifier: NCT00362596 - Completed
HIV; Herpes
- Iontophoretic Application of Acyclovir Cream to Treat Recurrent Herpes Labialis
ClinicalTrials.gov Identifier: NCT00230867 - Completed
Herpes Labialis
- Long-Term Oral Acyclovir Usage to Prevent Herpes Zoster Virus Infection After Bone Marrow Transplant
ClinicalTrials.gov Identifier: NCT00209352 - Completed
VZV Infection After Bone Marrow Transplantation
- Anti-Herpetic Treatment of Genital Ulcer : Effect on HIV & Herpes Shedding (ANRS 1212)
ClinicalTrials.gov Identifier: NCT00158483 - Completed
Ulcer; Herpes Genitalis
- SP-303T Applied to the Skin of Patients with Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success with Acyclovir
ClinicalTrials.gov Identifier: NCT00002310 - Completed
Herpes Simplex; HIV Infections
- Herpetic Eye Disease Study (HEDS) I
ClinicalTrials.gov Identifier: NCT00000138 - Completed
Keratitis, Herpetic; Ocular Herpes Simplex
- An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies
ClinicalTrials.gov Identifier: NCT00002272 - Completed
Herpes Simplex; HIV Infections
- Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine
ClinicalTrials.gov Identifier: NCT00000635 - Completed
Herpes Simplex; HIV Infections
- An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies
ClinicalTrials.gov Identifier: NCT00002021 - Completed
Herpes Simplex; HIV Infections
- A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001038 - Completed
Cytomegalovirus Infections; HIV Infections
- The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment
ClinicalTrials.gov Identifier: NCT00002144 - Completed
Herpes Simplex; HIV Infections
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