Article: Pioglitazone

Systematic (IUPAC) name
CAS number 111025-46-8
ATC code A10BG03
PubChem 4829
DrugBank APRD00653
Chemical data
Formula C19H20N2O3S
Mol. weight 356.44 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding > 99%
Metabolism  ?
Half life 3-7 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

In medicine and pharmacology, pioglitazone is a member of the drug class of the thiazolidinediones.

It is being marketed as Actos® by the pharmaceutical companies Takeda and Eli Lilly.

Like other thiazolidinediones, its mechanism of action is by activation the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARγ.

Side-effects and contraindications

See main article: thiazolidinedione

See also

  • Anti-diabetic drugs
  • Peroxisome proliferator-activated receptor


[ Disclaimer: The information on GoldBamboo for any particular treatment, medicine, drug, or herbal product might be missing or incomplete, and should never be used as a single source of knowledge. GoldBamboo generally has links to authoritative sites displayed toward the bottom of each topic page under the heading "Resources". ]