Pioglitazone

Actos

Article: Pioglitazone


Pioglitazone
Systematic (IUPAC) name
5-((4-(2-(5-ethyl-2-pyridinyl) ethoxy)phenyl)methyl)-,(+-)- 2,4-thiazolidinedione,
Identifiers
CAS number	111025-46-8
ATC code	A10BG03
PubChem	4829
DrugBank	APRD00653
Chemical data
Formula	C₁₉H₂₀N₂O₃S
Mol. weight	356.44 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	> 99%
Metabolism	?
Half life	3-7 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

In medicine and pharmacology, pioglitazone is a member of the drug class of the thiazolidinediones.

It is being marketed as Actos® by the pharmaceutical companies Takeda and Eli Lilly.

Like other thiazolidinediones, its mechanism of action is by activation the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARγ.

Side-effects and contraindications

See main article: thiazolidinedione

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Pioglitazone - Article

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Pioglitazone

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Article: Pioglitazone

Side-effects and contraindications

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Pioglitazone - Article

General Topics A-Z

Pioglitazone

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Article: Pioglitazone

Side-effects and contraindications

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