Trypsin

Trypsin(EC 3.4.21.4) family of serine proteases are enzymes that cleave proteins at the carboxyl side (or "C-terminus") of the basic amino acids lysine and arginine except when these two residues are followed by proline [1]. Trypsins are considered endopeptidases, i.e., the cleavage occurs within the polypeptide chain rather than at the terminal amino acids located at the ends of polypeptides. Chemistry and Function The reaction that trypsins catalyze is thermodynamically favorable but r ...