Sickle cell anemia (American English), sickle cell anaemia (British English) or sickle cell disease is a genetic disease in which red blood cells may change shape under certain circumstances. This causes the cells to become stuck in capillaries which deprives the downstream tissues of oxygen and causes ischemia and infarction. ...

GoldBamboo

... Why get tested?
To screen for the presence of sickle cell trait or to confirm the presence of sickle cell disease

When to get tested?
If you are an American of African descent, to determine if you carry one or both genes for sickle cell disease; prenatal screening also is available

Sample required?
A blood sample drawn from a vein in the arm; in children, a blood sample from a fingerstick or heelstick
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