HLA-B27 |
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Human Leukocyte Antigen B*27 (subtypes B*2701-2724) is a class I surface antigen encoded by the B locus in the MHC on chromosome 6. It presents microbial antigens to T-cells and is strongly associated with certain immunity diseases (SpA spondyloarthropathies). In the general population, about 8% Caucasian, 4% African, 2-9% Chinese, and 0.1-0.5% Japanese have the HLA-B27 antigen. In Northern Scandinavia (Lapland), 24% of people are HLA-B27 positive while 1.8% have ankylosing spondylitis (AS).
... Why get tested?
To determine whether you have human leukocyte antigen B27 (HLA-B27) on the surface of your cells. This test is sometimes ordered to help assess the likelihood that you have an autoimmune disorder that is associated with the presence of HLA-B27.
When to get tested?
When you have symptoms of chronic inflammation, pain, and stiffness in certain areas of your body, such as your back, neck, and chest, especially if you are male and the symptoms began in your early 30s.
Sample required?
A blood sample drawn from a vein in your arm
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Human Leukocyte Antigen B*27 (subtypes B*2701-2724) is a class I surface ant ...
Resources
- HLA-B27 (Lab Tests Online)

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