Her-2/neu |
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Also called ErbB2, HER-2/neu belongs to the EGFR family and is overexpressed in several solid tumors. Like EGFR, it is a tyrosine kinase receptor whose activation leads to proliferative signals within the cells. On activation, the HER family of receptors are known to form homodimers and heterodimers, each with a distinct signaling activity. ...
GoldBamboo
... Why get tested?
To determine whether a breast cancer tumor is positive for Her-2/neu, which helps to guide treatment and determine prognosis
When to get tested?
If you have been diagnosed with invasive breast cancer and your doctor wants to determine whether the Her-2/neu gene is being over-expressed in the tumor
Sample required?
A sample of breast cancer tissue obtained during a biopsy; sometimes a blood sample, drawn from a vein in your arm, is also required
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Lab Tests Online - more...
Resources
- Her-2/neu (Lab Tests Online)

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