Clinical Trial: Doctoral CRP On Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients

This study is currently recruiting patients.

Sponsored by: International Atomic Energy Agency
Information provided by: International Atomic Energy Agency

Purpose

1. To undertake clinical studies of radiotherapy with or without the administration of chemotherapeutic agent Cisplatin known to be radiosensitiser. 2. To perform pre-clinical studies of the radiosensitivity of human fibroblasts and cervix cancer cell lines in culture, with or without the addition of various HIV proteins or protease inhibitors, in order to determine the extent of any cellular radiosensitizing properties of these molecules. 3. To develop strategies for sensitising tumour cells to radiation, specifically by downregulating specific viral proteins that are known to be factors associated with resistance to radiotherapy
Condition Intervention Phase
Cancer of the Cervix
 Procedure: Radiotherapy alone and Radiotherapy with Cisplatin
Phase III

MedlinePlus related topics:  Cervical Cancer

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Female
Criteria

Inclusion Criteria: Cancer of the cervix, AIDS

    Exclusion Criteria: unable to give an informed consent -

    Location and Contact Information

    Please refer to this study by ClinicalTrials.gov identifier  NCT00122746

    Branislav Jeremic, M.D., Ph.D.      +43-1-2600  Ext. 21666    b.jeremic@iaea.org

    India
          Dr. Sarbani Ghosh Laskar, Dept. of Atomic Energy, TMC, Mumbai,  India; Recruiting
    Sarbani Ghosh Laskar

    Study chairs or principal investigators

    Branislav Jeremic, M.D., Ph.D.,  Study Director,  International Atomic Energy Agency   

    More Information

    Study ID Numbers:  E33022
    Record last reviewed:  July 2005
    Last Updated:  July 25, 2005
    Record first received:  July 21, 2005
    ClinicalTrials.gov Identifier:  NCT00122746
    Health Authority: United Nations: International Atomic Energy Agency
    ClinicalTrials.gov processed this record on 2005-07-26

    Resources

    • CRP (Lab Tests Online)



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