Skin Diseases (General) |
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Clinical Trial: Studies of Patients with Skin Disease, Patients with Neurological Degenerations, and Normal Volunteers
This study has been completed.
Purpose
It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.
| Condition |
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| Healthy Muscular Dystrophy Retinal Degeneration Skin Diseases Virus Diseases |
MedlinePlus related topics: Muscular Dystrophy; Retinal Disorders; Skin Diseases; Viral Infections
Study Type: Observational
Study Design: Natural History
Expected Total Enrollment: 9999
Study start: July 17, 1978; Study completion: June 23, 2000
It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.
Eligibility
Genders Eligible for Study: Both
Accepts Healthy Volunteers
Criteria
Patients with neurological degenerations are eligible, including patients with inflammatory, neoplastic and viral skin diseases and also heterozygous carriers of such inherited diseases.
Volunteers without skin diseases are eligible, except children.
Location Information
Maryland
National Cancer Institute (NCI), 9000 Rockville Pike, Bethesda, Maryland, 20892, United States
More Information
Publications
Kraemer KH, Coon HG, Petinga RA, Barrett SF, Rahe AE, Robbins JH. Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc Natl Acad Sci U S A. 1975 Jan;72(1):59-63.
Yaoita H, Katz SI. Immunoelectronmicroscopic localization of IgA in skin of patients with dermatitis herpetiformis. J Invest Dermatol. 1976 Oct;67(4):502-6.
Record last reviewed: June 1, 2000
Last Updated: December 11, 2002
Record first received: November 3, 1999
ClinicalTrials.gov Identifier: NCT00001164
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Mastocytosis (National Institute of Allergy and Infectious Diseases)
- NIGMS-Supported Basic Research on Skin Replacement Following Burn or Trauma Injury (National Institute of General Medical Sciences)

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