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Studies of Patients with Skin Disease, Patients with Neurological Degenerations, and Normal Volunteers - Article


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Skin Diseases (General)

 




Clinical Trial: Studies of Patients with Skin Disease, Patients with Neurological Degenerations, and Normal Volunteers

This study has been completed.

Sponsored by: National Cancer Institute (NCI)
Information provided by: Warren G Magnuson Clinical Center (CC)

Purpose

It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.

Condition
Healthy
Muscular Dystrophy
Retinal Degeneration
Skin Diseases
Virus Diseases

MedlinePlus related topics:  Muscular Dystrophy;   Retinal Disorders;   Skin Diseases;   Viral Infections

Study Type: Observational
Study Design: Natural History

Further Study Details: 

Expected Total Enrollment:  9999

Study start: July 17, 1978;  Study completion: June 23, 2000

It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.

Eligibility

Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Patients with skin diseases of presumed genetic, immunologic, or virologic origin are eligible.
Patients with neurological degenerations are eligible, including patients with inflammatory, neoplastic and viral skin diseases and also heterozygous carriers of such inherited diseases.
Volunteers without skin diseases are eligible, except children.

Location Information


Maryland
      National Cancer Institute (NCI), 9000 Rockville Pike,  Bethesda,  Maryland,  20892,  United States

More Information

Publications

Kraemer KH, Coon HG, Petinga RA, Barrett SF, Rahe AE, Robbins JH. Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc Natl Acad Sci U S A. 1975 Jan;72(1):59-63.

Yaoita H, Katz SI. Immunoelectronmicroscopic localization of IgA in skin of patients with dermatitis herpetiformis. J Invest Dermatol. 1976 Oct;67(4):502-6.

Study ID Numbers:  780099; 78-C-0099
Record last reviewed:  June 1, 2000
Last Updated:  December 11, 2002
Record first received:  November 3, 1999
ClinicalTrials.gov Identifier:  NCT00001164
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005

Resources



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December 2, 2009



Page Updated: September 6, 2005
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