Avascular Necrosis |
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Avascular necrosis is a disease resulting from the temporary or permanent loss of the blood supply to the bones. Without blood, the bone tissue dies and causes the bone to collapse. If the process involves the bones near a joint, it often leads to collapse of the joint surface. This disease also is known as osteonecrosis, aseptic necrosis, and ischemic bone necrosis. There are many causes of avascular necrosis such as alcoholism, excessive steroid use, post trauma and Caisson's disease. In ...
Wikipedia - [full article]
Avascular Necrosis Clinical Trials
- Atorvastatin to Prevent Avascular Necrosis of Bone in Steroid Treated Exacerbated Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00412841 - Recruiting
Avascular Necrosis
- Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease
ClinicalTrials.gov Identifier: NCT00006130 - Active, not recruiting
Bone Avascular Necrosis; Sickle Cell Anemia
- Study of the HemiCAP™ Unicondylar Femoral Resurfacing Prosthesis."
ClinicalTrials.gov Identifier: NCT00158444 - Recruiting
Osteoarthritis; Avascular Necrosis
- Molecular Genetic Study of Avascular Necrosis of the Femoral Head
ClinicalTrials.gov Identifier: NCT00260897 - Recruiting
Osteonecrosis
- A Clinical Investigation of the Oxford® Meniscal Unicompartmental Knee System
ClinicalTrials.gov Identifier: NCT00578994 - Recruiting
Osteoarthritis; Avascular Necrosis
- Randomized Fixed Bearing vs Mobile Bearing Cruciate Retaining TKA
ClinicalTrials.gov Identifier: NCT00289094 - Active, not recruiting
Osteoarthritis,; Rheumatoid Arthritis,; Avascular Necrosis of Bone
- Clinical Study Evaluating an Acetabular Cup System After Total Hip Replacement
ClinicalTrials.gov Identifier: NCT00306930 - Active, not recruiting
Osteoarthritis; Rheumatoid Arthritis; Arthritis; Avascular Necrosis; Acute Fracture
- Primary TKA Cruciate Retaining vs Cruciate Substituting With Rotating Platform Knee Prostheses
ClinicalTrials.gov Identifier: NCT00289081 - Active, not recruiting
Osteoarthritis,; Rheumatoid or Other Inflammatory Arthritis, Avascular Necrosis (AVN) of Bone.
- A Clinical Investigation of the C2a-Taper™ Acetabular System
ClinicalTrials.gov Identifier: NCT00578851 - Recruiting
Osteoarthritis; Avascular Necrosis; Congenital Hip Dysplasia; Traumatic Arthritis
- Clinical Study Comparing Two Implant Surface Finishes in Patients Undergoing Cementless Total Hip Replacement
ClinicalTrials.gov Identifier: NCT00306917 - Active, not recruiting
Osteoarthritis; Rheumatoid Arthritis; Post-Traumatic Arthritis; Avascular Necrosis; Acute Fracture
- Comparison of Hip Resurfacing to Large Femoral Head Total Hip Arthroplasty
ClinicalTrials.gov Identifier: NCT00175487 - Recruiting
Osteoarthritis; Avascular Necrosis
- Post-Approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System
ClinicalTrials.gov Identifier: NCT00546598 - Recruiting
Non-Inflammatory Joint Disease; Osteoarthritis; Avascular Necrosis; Congenital Hip Dysplasia; Post-Traumatic Arthritis
- Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy
ClinicalTrials.gov Identifier: NCT00106756 - Recruiting
Exudatiaon; Avascular Retina; Retina Fold
- Biological Therapy in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00005853 - Active, not recruiting
Myelodysplastic Syndromes
- Diffusion Tensor MRI to Distinguish Brain Tumor Recurrence From Radiation Necrosis
ClinicalTrials.gov Identifier: NCT00285324 - Recruiting
Glioma Tumor Recurrence; Radiation Necrosis; Primary Brain Tumor
- NGR-TNF in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00098943 - Active, not recruiting
adult solid tumor; Endocrine Cancer; Gastrointestinal Cancer; Head and Neck Cancer; kidney and urinary cancer
- Measurement of Bite Force in Humans
ClinicalTrials.gov Identifier: NCT00223327 - Recruiting
Dental Pulp Necrosis; Periapical Periodontitis
- Assessment of a New Apexification Method for Patients Presenting a Non Vital Immature Tooth
ClinicalTrials.gov Identifier: NCT00472173 - Recruiting
Dental Pulp Necrosis
- Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption
ClinicalTrials.gov Identifier: NCT00427804 - Recruiting
Rheumatoid Arthritis; Crohn's Disease
- Examine the Possible Association of Hepatic CYP3A Activity and the Susceptibility to Femur Head Necrosis
ClinicalTrials.gov Identifier: NCT00244400 - Completed
Femur Head Necrosis
- Effectiveness of Two Types of Treatment in Restoring Muscle After Hip Surgery
ClinicalTrials.gov Identifier: NCT00393848 - Recruiting
Hip Fracture; Osteoarthritis; Femur Head Necrosis
- Limb Perfusion of Melphalan, with or without Tumor Necrosis Factor, to Treat Inoperable Arm or Leg Cancer
ClinicalTrials.gov Identifier: NCT00001831 - Completed
Sarcoma
- A Pilot Study to Examine the Feasibility and Effect of Tumor Necrosis Factor (TNF) Inhibition on HIV Disease
ClinicalTrials.gov Identifier: NCT00205231 - Recruiting
HIV Infections
- Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg
ClinicalTrials.gov Identifier: NCT00003789 - Completed
stage III melanoma; Recurrent Melanoma
- Influence of Sutent on Tumor Vascularization and Necrosis in Patients With Renal Cell Carcinoma
ClinicalTrials.gov Identifier: NCT00509704 - Recruiting
Renal Cell Cancer
- A Study to Evaluate the Ability of TNFR:Fc to Decrease the Amount of IL-6 (Interleukin-6) and TNF-alpha (Tumor Necrosis Factor) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001116 - Completed
HIV Infections
- Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer
ClinicalTrials.gov Identifier: NCT00436410 - Recruiting
Adrenocortical Carcinoma; Breast Cancer; Colorectal Cancer; Kidney Cancer; Liver Cancer; Melanoma (Skin); Ovarian Cancer; Pancreatic Cancer
- A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients with AIDS Related Complex
ClinicalTrials.gov Identifier: NCT00001004 - Completed
HIV Infections
- The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated with Juvenile Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00012506 - Recruiting
Uveitis; Arthritis, Juvenile Rheumatoid
- A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00002262 - Completed
Sarcoma, Kaposi; HIV Infections
- Blocking Tumor Necrosis Factor in Ankylosing Spondylitis
ClinicalTrials.gov Identifier: NCT00000433 - Completed
Spondylitis, Ankylosing
- Beta Alethine in Treating Patients With Myeloma
ClinicalTrials.gov Identifier: NCT00006466 - Active, not recruiting
monoclonal gammopathy of undetermined significance; stage I multiple myeloma; stage II multiple myeloma; extramedullary plasmacytoma; ...
- Infliximab in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00074074 - Active, not recruiting
refractory anemia with excess blasts; refractory anemia with ringed sideroblasts; Refractory Anemia; de novo myelodysplastic syndromes; ...
- Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma
ClinicalTrials.gov Identifier: NCT00006113 - Active, not recruiting
stage III melanoma; Stage IV Melanoma; Recurrent Melanoma
- Azacitidine and Etanercept in Treating Patients with Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00118287 - Recruiting
de novo myelodysplastic syndromes; previously treated myelodysplastic syndromes; secondary myelodysplastic syndromes; ...
- Infliximab in Treating Fatigue in Postmenopausal Women Who Have Undergone Treatment for Stage 0, Stage I, or Stage II Breast Cancer
ClinicalTrials.gov Identifier: NCT00112749 - Recruiting
stage I breast cancer; stage II breast cancer; breast cancer in situ; Fatigue
- ALBION "Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis"
ClinicalTrials.gov Identifier: NCT00360386 - Completed
Ischemia
- GVH 022P: Study Using Anti Tumor Necrosis Factor Antibody (Infliximab) for Treatment of Acute Graft Versus Host Disease
ClinicalTrials.gov Identifier: NCT00228839 - Completed
Graft Vs Host Disease
- Effects of Tumor Necrosis Factor (TNF)-alpha Antagonism in Patients with Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00111956 - Completed
Metabolic Syndrome X
- Hyperthermic Isolated Limb Perfusion and Melphalan with or without Tumor Necrosis Factor to Treat Advanced Melanoma in a Limb
ClinicalTrials.gov Identifier: NCT00056732 - Completed
Malignant Melanoma
- Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS
ClinicalTrials.gov Identifier: NCT00000646 - Completed
HIV Infections
- A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion with Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients with Locally Advanced Extremity Melanoma
ClinicalTrials.gov Identifier: NCT00001296 - Completed
Melanoma
- Gene Therapy Combined With Chemotherapy and Radiation Therapy in Treating Patients With Pancreatic Cancer That Cannot Be Surgically Removed
ClinicalTrials.gov Identifier: NCT00049647 - No longer recruiting
adenocarcinoma of the pancreas; stage III pancreatic cancer
- Home Treatment of HIV-Infected Patients with Interleukin-2 with or without a Tumor Necrosis Factor Antagonist
ClinicalTrials.gov Identifier: NCT00001475 - Completed
Acquired Immunodeficiency Syndrome; HIV Infection
- ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00048321 - Completed
Rheumatoid Arthritis
- Phase III Randomized Study of Anti-Tumor Necrosis Factor Chimeric Monoclonal Antibody (cA2) for Patients with Enterocutaneous Fistulae as a Complication of Crohn's Disease
ClinicalTrials.gov Identifier: NCT00004941 - Completed
Crohn's Disease
- Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg
ClinicalTrials.gov Identifier: NCT00019968 - Completed
Stage IVB Adult Soft Tissue Sarcoma; Stage IIB Adult Soft Tissue Sarcoma; Stage IIC Adult Soft Tissue Sarcoma; Recurrent Adult Soft Tissue Sarcoma; Stage IVA Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma
- MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery)
ClinicalTrials.gov Identifier: NCT00157716 - Completed
Coronary artery bypass graft surgery; Myocardial Ischemia; Reperfusion Injury; Myocardial Revascularization
- Arsenic Trioxide and Etanercept in Treating Patients With Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00093366 - Completed
de novo myelodysplastic syndromes; previously treated myelodysplastic syndromes; secondary myelodysplastic syndromes; ...
Resources
- Avascular Necrosis (Cleveland Clinic)
- Avascular Necrosis: Questions & Answers (Cleveland Clinic)

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