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Post-Traumatic Stress Disorder (PTSD) Symptom Study - Article


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Post Traumatic Stress Disorder/ptsd

 




Clinical Trial: Post-Traumatic Stress Disorder (PTSD) Symptom Study

This study has been completed.

Sponsored by: Department of Veterans Affairs
Information provided by: Department of Veterans Affairs

Purpose

The primary goals for this investigation are to quantify: (1) fluctuations in PTSD symptom reports when assessed at bi-weekly intervals; (2) change in PTSD symptoms associated with stressful life events; and (3) change in PTSD symptoms associated with perceived social support.

Condition
PTSD

MedlinePlus related topics:  Post-Traumatic Stress Disorder

Study Type: Observational
Study Design: Natural History, Longitudinal, Defined Population, Retrospective/Prospective Study

Official Title: Longitudinal Evaluation of Chronic Combat-Related PTSD

Further Study Details: 

Study start: April 2000;  Study completion: April 2003

The primary goals for this investigation are to quantify: (1) fluctuations in PTSD symptom reports when assessed at bi-weekly intervals; (2) change in PTSD symptoms associated with stressful life events; and (3) change in PTSD symptoms associated with perceived social support.

Despite increased sophistication in measurement of PTSD, little is known about the long-term longitudinal course of this disorder or the fluctuation of symptoms over time. Because previous studies have focused on the development and persistence of symptoms immediately following a stressor, the course of the chronic disorder has been largely unexplored. Although there is evidence of both persistence and fluctuation of PTSD symptom presentation in Vietnam veterans, little is known about how much and in what ways symptoms change over time. This investigation will increase understanding of the nature and extent of symptom fluctuation as well as the longitudinal course of PTSD as first steps in determining which variables affect that course and how clinicians might intervene to alter it.

Aversive life events may constitute one factor that influences the course of chronic PTSD. Researchers and clinicians have frequently hypothesized that stressful life events account for much of the variability in course of chronic PTSD (Green, 1994; Resnick, Kilpatrick, and Lipovsky, 199 1); individuals with PTSD may have a compromised ability to cope with stressors, and such events may worsen existing symptoms. Social support is another variable thought to affect the course of post-trauma symptomatology. Support from other persons has been shown to both promote psychological health in general and to protect against psychological deterioration in times of stress (e.g., Cassel, 1976; Cohen and Wills, 1985, Nornis and Kamasty, 1996). This investigation will examine aversive life events and perceived social support to determine their relationships over time to symptoms of PTSD.

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Male

Accepts Healthy Volunteers

Criteria

1) Vietnam vets who served in combat

2) Diagnosis of current or lifetime PTSD

Excluded if severe psychosis, current diagnosis of acute substance dependence, if no stable residence in past 6 months


Location Information


Massachusetts
      VA Boston Healthcare System, Boston,  Massachusetts,  02130,  United States

More Information

Study ID Numbers:  MHBS-001-99F
Record last reviewed:  December 2004
Last Updated:  December 30, 2004
Record first received:  July 3, 2001
ClinicalTrials.gov Identifier:  NCT00018798
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005

Resources



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December 5, 2009



Page Updated: September 6, 2005
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