In this disease the lack of an enzyme, Arylsufatase-A (ASA), causes the accumulation of sulfatide deposits in the brain, which in turn leads to myelin breakdown.

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Metachromatic leukodystrophy (MLD) is the most common form of a family of g ...
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Metachromatic Leukodystrophy
... What is Metachromatic Leukodystrophy? Metachromatic leukodystrophy (MLD) is one of a group of genetic disorders called the leukodystrophies. These are diseases that impair the growth or development of...
Source: Cleveland Clinic

Metachromatic Leukodystrophy Information Page
... Metachromatic leukodystrophy (MLD) is one of a group of genetic disorders called the leukodystrophies. These are diseases that impair the growth or development of the myelin sheath, the fatty covering...
Source: National Institute of Neurological Disorders and Stroke

   

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