Not Signed In -
Friedreich's Ataxia |
FA - Friedreich ataxia; FRDA; Friedreich ataxia; Hereditary spinal ataxia; Hereditary Spinal Sclerosis; Spinocerebellar Ataxia, Friedreich |
Clinical Trial: Clinical and Molecular Correlations in Spinocerebellar Ataxia Type 10 (SCA10)
This study is currently recruiting patients.
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Purpose
OBJECTIVES: I. Clinically evaluate members from families with dominantly inherited ataxias and collect blood samples for detailed molecular studies. II. Perform detailed clinical evaluations on patients with recessively inherited ataxias.
| Condition |
|---|
| Hereditary Ataxia |
MedlinePlus related topics: Brain Diseases; Degenerative Nerve Diseases; Genetic Disorders; Spinal Cord Diseases
Study Type: Observational
Study Design: Screening
Expected Total Enrollment: 30
Study start: November 1999
PROTOCOL OUTLINE: Participants undergo a comprehensive clinical and molecular evaluation. Studies include: neurologic evaluation, including magnetic resonance imaging and nerve conduction studies; ophthalmologic exam; audiologic exam, including auditory brain stem evoked response; DNA extraction for lymphoblastoid cell lines; gene mapping; and linkage analysis. A neuropathologic evaluation is conducted postmortem, when possible. Patients with recessive ataxia also receive a developmental assessment.
Eligibility
Genders Eligible for Study: Both
Criteria
- Patients with recessive ataxia
- Members of families with dominantly inherited ataxia
Location and Contact Information
Texas
University of Texas Medical Branch at Galveston, Galveston, Texas, 77555, United States; Recruiting
Tetsuo Ashizawa, Study Chair, Baylor College of Medicine
More Information
Record last reviewed: January 2005
Last Updated: January 21, 2005
Record first received: October 18, 1999
ClinicalTrials.gov Identifier: NCT00004306
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 8, 2005
Resources
- Friedreich's ataxia (Google Health)
- Friedreich's Ataxia (National Institute of Neurological Disorders and Stroke)
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