Not Signed In -
Vascular Headache |
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Clinical Trial: The Role of CGRPand Nociceptin in Migraine
This study is currently recruiting patients.
Verified by National Taiwan University Hospital June 2005
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Purpose
The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.
| Condition |
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| Migraine Headache |
MedlinePlus related topics: Headache; Migraine
Study Type: Observational
Study Design: Screening, Cross-Sectional, Defined Population, Prospective Study
Official Title: The Role of Calcitonin Gene-Related Peptide(CGRP)and Nociceptin in the Pathogenesis of Migraine
Further Study Details:
Expected Total Enrollment: 200
Study start: January 2005; Expected completion: December 2005
Last follow-up: June 2005; Data entry closure: November 2005
The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples of migraineurs for analysis of these neuropeptides.
Eligibility
Ages Eligible for Study: 3 Years - 50 Years, Genders Eligible for Study: Both
Accepts Healthy Volunteers
Criteria
Inclusion Criteria: patients with headache -
Exclusion Criteria: fever, congenital anomaly, CNS organic lesions
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Location and Contact Information
Please refer to this study by ClinicalTrials.gov identifier NCT00155129
Pi-Chuan Fan, MD pcfan@ntumc.org
Li-Chu Chiou, PhD
Li-Chu Chiou, PhD
Taiwan
Department of Pediatrics, Taipei, Taiwan; Recruiting
Pi-Chuan Fan, MD 886-2-23123456 Ext. 5135 pcfan@ntumc.org
Pi-Chuan Fan, MD, Principal Investigator
Pi-Chuan Fan, MD, Principal Investigator
Study chairs or principal investigators
Pi-Chuan Fan, Principal Investigator, Department of Pediatric, NTUH
More Information
Study ID Numbers: 9361701099; 9361701099
Last Updated: September 9, 2005
Record first received: September 9, 2005
ClinicalTrials.gov Identifier: NCT00155129
Health Authority: Taiwan: Department of Health
ClinicalTrials.gov processed this record on 2005-09-13
Last Updated: September 9, 2005
Record first received: September 9, 2005
ClinicalTrials.gov Identifier: NCT00155129
Health Authority: Taiwan: Department of Health
ClinicalTrials.gov processed this record on 2005-09-13
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