Sports Injuries |
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Clinical Trial: Therapy for Reading Problems in Adults After Brain Injury
This study is currently recruiting patients.
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Purpose
Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
| Condition | Treatment or Intervention |
|---|---|
| Dyslexia, Acquired Brain Injuries Cerebrovascular Accident | Behavior: Cognitive Therapy to Improve Reading |
MedlinePlus related topics: Head and Brain Injuries; Learning Disorders; Mental Health; Stroke
Study Type: Interventional
Study Design: Treatment, Non-Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title: Cognitively-based Treatments of Acquired Dyslexias
Expected Total Enrollment: 58
Study start: October 1994
Acquired disorders of reading (acquired dyslexia) are common in patients with aphasia subsequent to left hemisphere stroke. Even when language functions recover sufficiently to enable the patient to return to work, continuing dyslexia often interferes significantly with job performance. This study will evaluate cognitive therapies for the treatment of acquired dyslexia.
Each therapy is based upon a cognitive neuropsychological model of reading; the therapies target specific types of reading deficit and stem from the question of re-learning versus re-organization of function. The therapies focus on dyslexic disorders stemming from the following underlying deficits: 1) impaired access to the orthographic word form from the visual modality (pure alexia); 2) impaired orthographic/phonologic connections (phonologic/deep dyslexia); and 3) decreased ability to hold phonologic codes in memory (phonologic text alexia).
Participants in this study will undergo a comprehensive and detailed battery of reading and reading-related tests to determine the underlying impairment causing the reading deficit. Based upon the results of these tests, the patient's dyslexic disorder will be characterized and, if appropriate, the patient will be assigned to one of the treatment programs devised specifically for that type of deficit. Treatment programs are evaluated for efficacy by comparing the accuracy and speed of reading pre- and post-treatment.
Eligibility
Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both
Criteria
Inclusion Criteria
- Reading deficit subsequent to stroke, traumatic brain injury, brain surgery, or other brain damage
Exclusion Criteria
- History of developmental dyslexia or learning disabilities
- Best corrected vision less than 20/40
- Less than 10 years of formal education
- Significant memory or comprehension problems
Location and Contact Information
District of Columbia
Georgetown University Medical Center, Washington, District of Columbia, 20057, United States; Recruiting
Rhonda B. Friedman, Ph.D., Principal Investigator, Georgetown University Medical School
More Information
Publications
Friedman RB, Lott SN. Rapid word identification in pure alexia is lexical but not semantic. Brain Lang. 2000 May;72(3):219-37.
Nitzberg Lott S, Friedman RB. Can treatment for pure alexia improve letter-by-letter reading speed without sacrificing accuracy? Brain Lang. 1999 May;67(3):188-201.
Record last reviewed: September 2003
Last Updated: October 13, 2004
Record first received: July 14, 2003
ClinicalTrials.gov Identifier: NCT00064805
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005

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