NT-proBNP for Diagnosis and Resource Utilization in Patients with Acute Dyspnoea - Article Water Retention
Clinical Trial: NT-proBNP for Diagnosis and Resource Utilization in Patients with Acute Dyspnoea
This study is currently recruiting patients.
Verified by University Hospital Mannheim August 2005
Evaluation of the sensitivity and specificity of NT-proBNP-measurement for the diagnosis of heart failure in patients with acute dyspnoea and/or edema. Determination of the exact NT-proBNP-cut-off point(s) for the differentiation of healthy persons, patients with acute heart failure and patients with dyspnoea of other origin.
Evaluation of treatment costs in patients with dyspnoea under special consideration of NT-proBNP-measurement.
|Heart Failure |
|Phase IV |
MedlinePlus related topics: Cardiomyopathy; Edema
Study Type: Observational
Study Design: Screening, Cross-Sectional, Defined Population, Retrospective/Prospective Study
Expected Total Enrollment: 400
Study start: June 2005; Expected completion: October 2007
Last follow-up: October 2006; Data entry closure: June 2007
Sensitivity and specificity of NT-proBNP measurement for discrimination of heart failure from dyspnoea of other origin.
Determination of NT-proBNP-Cut-off(s) Determination of treatment costs Evaluation of resource savings when implementing NT-proBNP for determination of diagnosis.
Time to diagnosis. Hospitalization rate /Intensive care treatment rate Duration of hospital stay 30-Day re-hospitalization rate 30 day mortality rate and adverse event rate
- Age 18-90 years
- Dyspnoea or/and peripheral edema
- Informed consent
- Renal insufficiency with creatinine > 2.8mg/dl
- Anemia (hemoglobin < 8.0mg/dl)
Location and Contact Information
Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Mannheim, Baden-Württemberg, 68167, Germany; Recruiting
Martina Brueckmann, MD, Sub-Investigator
Michael Neumaier, MD, Principal Investigator
Parviz Ahmad-Nejad, MD, Sub-Investigator
Martin Borggrefe, MD, Principal Investigator
Martina Brueckmann, MD, Principal Investigator, I. Medical Department, University Hospital Mannheim
Martin Borggrefe, MD, Study Director, I. Medical Department, University Hospital Mannheim
Michael Neumaier, MD, Study Chair, Institute of Clinical Chemistry, University Hospital Mannheim
Parviz Ahmad-Nejad, MD, Study Chair, Institute of Clinical Chemistry, University Hospital Mannheim
Last Updated: September 1, 2005
Record first received: August 31, 2005
ClinicalTrials.gov Identifier: NCT00143793
Health Authority: Germany: Federal Institute for Drugs and Medicinal Devices
ClinicalTrials.gov processed this record on 2005-09-06
- ClinicalTrials.gov: Edema (National Institutes of Health)
- DASH Eating Plan (National Heart, Lung, and Blood Institute) - Links to PDF File