Diabetes Insipidus

For the disease most commonly associated with the generic term "diabetes", see Diabetes mellitus. Diabetes insipidus (DI) is a disease characterized by excretion of large amounts of severely diluted urine, which cannot be reduced when fluid intake is reduced. It denotes inability of the kidney to concentrate urine. DI is caused by a deficiency of antidiuretic hormone, or by an insensitivity of the kidneys to that hormone. Signs and symptoms Excessive urination and extreme thirst (espe ...