Clinical Trial: Treatment for Depression in the Primary Care Setting

This study is currently recruiting patients.

Sponsored by: National Institute of Mental Health (NIMH)
Information provided by: National Institute of Mental Health (NIMH)

Purpose

The purpose of this study is to determine whether a brief form of counseling is more effective than usual care in treating patients with minor depression in the primary care setting. This study will also examine the relationship between patient characteristics (social support, adverse life events, personality traits, and comorbidity) and remission of minor depression.

Condition Treatment or Intervention Phase
Depression
 Behavior: Problem-Solving Treatment for Primary Care
Phase IV

MedlinePlus related topics:  Depression

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study

Official Title: Problem-Solving Treatment for Primary Care Depression

Further Study Details: 

Expected Total Enrollment:  300

Study start: December 2002

Minor depression is one of the most common types of depressive disorders seen in primary care. The effectiveness and tolerability of antidepressants in patients with minor depression is unclear, and the development of alternative treatments is necessary.

In the first phase of this study, participants are observed for 4 weeks to identify those most in need of depression-specific treatment. Participants are then exposed to the Problem-Solving Treatment for Primary Care (PST-PC), a six-session behavioral treatment for depression. After 4 weeks, patients who do not respond adequately to the treatment are randomly assigned to either continued PST-PC or to usual care for 9 weeks. Participants are followed for 6 months after the study.

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

  • Primary care patient at Dartmouth-Hitchcock Medical Center (DHMC)
  • Hamilton Depression Score >= 10 and minor depression at time of entry and after 4 weeks of observation

Exclusion Criteria:

  • Psychosis, Obsessive Compulsive Disorder (OCD), or Post Traumatic Stress Disorder (PTSD)
  • Active substance abuse
  • Receiving treatment for depression

Location and Contact Information


New Hampshire
      Dartmouth-Hitchcock Medical Center, Lebanon,  New Hampshire,  03756,  United States; Recruiting
Cynthia Hewitt  603-653-3570 
Angelica Barrett  603-653-3570 

More Information

Study ID Numbers:  62322-01A2
Record last reviewed:  October 2004
Last Updated:  October 18, 2004
Record first received:  February 25, 2003
ClinicalTrials.gov Identifier:  NCT00055328
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005