Clinical Trial: Clinician Managed Interpersonal Psychotherapy

This study is currently recruiting patients.

Sponsored by: National Institute of Mental Health (NIMH)
Information provided by: National Institute of Mental Health (NIMH)


This study will compare the long-term effectiveness of Clinician-Managed Interpersonal Psychotherapy (CM-IPT) and standard IPT for treatment of postpartum depression. It will also evaluate the acute effectiveness of CM-IPT for postpartum depression.

Condition Treatment or Intervention
Depression, Postpartum
 Behavior: Interpersonal Psychotherapy (IPT)
 Behavior: Clinician Managed Interpersonal Psychotherapy (CM-IPT)

MedlinePlus related topics:  Postpartum Depression

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study

Further Study Details: 

Expected Total Enrollment:  160

CM-IPT is delivered in 12 sessions over the course of a year. Standard IPT is delivered in 12 sessions in the first 12 weeks after treatment assignment.


Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Female

Accepts Healthy Volunteers


Inclusion criteria:

  • Women between 8 and 24 weeks postpartum
  • Meet DSM-IV criteria for Major Depression
  • Hamilton Rating Scale for Depression score of 12 or more

Exclusion criteria:

  • Active substance abuse
  • Psychotic disorders

Location and Contact Information

      University of Iowa, Iowa City,  Iowa,  52242,  United States; Recruiting
Scott Stuart, M.D.  319-353-6960 
Michael W O'Hara, Ph.D. 

More Information

Study ID Numbers:  59668-01A2
Record last reviewed:  September 2004
Last Updated:  October 13, 2004
Record first received:  August 9, 2002 Identifier:  NCT00043602
Health Authority: United States: Federal Government processed this record on 2005-04-08

Cache Date: April 9, 2005