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Sepsis |
Blood Poisoning; Septic Shock; Septicemia |
Sepsis (in Greek Σήψις, putrefaction) is a serious medical condition, resulting from the immune response to a severe infection. Septicemia is sepsis of the bloodstream caused by bacteremia, which is the presence of bacteria in the bloodstream. The term septicemia is also used to refer to sepsis in general. Symptoms The immunological response that causes sepsis is a systemic inflammatory response causing widespread activation of inflammation and coagulation pathways. This may progre ...
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Sepsis Clinical Trials
- BaSES Trial: Basel Starch Evaluation in Sepsis
ClinicalTrials.gov Identifier: NCT00273728 - Recruiting
Sepsis; Severe Sepsis; Septic Shock
- The Effects of EPA, GLA and Antioxidants in the Treatment of Sepsis
ClinicalTrials.gov Identifier: NCT00329680 - Recruiting
Sepsis; Severe Sepsis; Septic Shock
- Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests
ClinicalTrials.gov Identifier: NCT00258869 - Recruiting
Sepsis; Septicemia; Sepsis Syndrome; Shock, Septic; Pneumonia
- Sepsis: Prognosis and Evaluation of Early Diagnosis and Intervention (SPEEDI Study)
ClinicalTrials.gov Identifier: NCT00389337 - Active, not recruiting
SIRS; Sepsis
- Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.
ClinicalTrials.gov Identifier: NCT00318552 - Active, not recruiting
Sepsis
- Assessment of pleconaril for treatment of enteroviral sepsis syndrome in neonates
ClinicalTrials.gov Identifier: NCT00031512 - Not yet recruiting
Sepsis
- Effect of APC and Epo on the Inflammatory Response During Sepsis.
ClinicalTrials.gov Identifier: NCT00229034 - Recruiting
Sepsis; Systemic Inflammation
- The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis
ClinicalTrials.gov Identifier: NCT00493415 - Recruiting
Sepsis; Septic Shock
- Regulation of Endocrine, Metabolic, Immune and Bioenergetic Responses in Sepsis
ClinicalTrials.gov Identifier: NCT00187824 - Recruiting
Sepsis; Critical Illness
- Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00464204 - Recruiting
Sepsis
- Multi-Marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET)
ClinicalTrials.gov Identifier: NCT00472628 - Recruiting
Sepsis
- Procalcitonin-Guided Antimicrobial Discontinuation
ClinicalTrials.gov Identifier: NCT00250666 - Recruiting
Sepsis
- Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation
ClinicalTrials.gov Identifier: NCT00372502 - Recruiting
Severe Sepsis; Septic Shock
- Prevention of Infection in Indian Neonates
ClinicalTrials.gov Identifier: NCT00098176 - Recruiting
Sepsis
- Methylene Blue in Sepsis: A Randomized Controlled Trial
ClinicalTrials.gov Identifier: NCT00486174 - Recruiting
Sepsis
- Cytokine Removal by CRRT in Pediatric Sepsis
ClinicalTrials.gov Identifier: NCT00537693 - Recruiting
Sepsis
- Polymyxin-B Protects From Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial
ClinicalTrials.gov Identifier: NCT00490477 - Recruiting
Gram-Negative Bacterial Infections; Sepsis
- Effect of Rosuvastatin in Abdominal Sepsis
ClinicalTrials.gov Identifier: NCT00357123 - Recruiting
Sepsis
- The Utility of Ischemia Modified Albumin (IMA) in Sepsis
ClinicalTrials.gov Identifier: NCT00448968 - Completed
Sepsis; Severe Sepsis; Systemic Inflammatory Response Syndrome; Sepsis Syndrome
- Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis
ClinicalTrials.gov Identifier: NCT00222222 - Recruiting
Inflammation, Sepsis, SIRS
- ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00334828 - Recruiting
Severe Sepsis
- Statin for Immunomudulation in Sepsis
ClinicalTrials.gov Identifier: NCT00452608 - Recruiting
Sepsis
- Evaluate Impact to Protein C Levels With Changing Dose/Duration of Drotrecogin Alfa (Activated) Administered to Severe Sepsis Patients
ClinicalTrials.gov Identifier: NCT00386425 - Recruiting
Severe Sepsis
- Pharmacokinetic of Ceftriaxone in Septic ICU Patients
ClinicalTrials.gov Identifier: NCT00449800 - Recruiting
Sepsis; Severe Sepsis; Septic Shock
- Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis
ClinicalTrials.gov Identifier: NCT00559130 - Recruiting
Acute Respiratory Distress Syndrome; Acute Lung Injury; Sepsis
- Near Infrared Spectroscopy (NIRS) in Severe Sepsis
ClinicalTrials.gov Identifier: NCT00167596 - Recruiting
Critical Illness; Severe Sepsis
- Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study)
ClinicalTrials.gov Identifier: NCT00488917 - Recruiting
Liver Diseases; Liver Cirrhosis; Sepsis; Critical Illness
- A Study in Sepsis Patients With Renal Failure
ClinicalTrials.gov Identifier: NCT00511186 - Not yet recruiting
Sepsis; Bacterial Infections and Mycoses
- Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis
ClinicalTrials.gov Identifier: NCT00541827 - Not yet recruiting
Severe Sepsis; Septic Shock
- Unfractioned Heparin for Treatment of Sepsis
ClinicalTrials.gov Identifier: NCT00100308 - Recruiting
Sepsis; Bacterial Infections
- A Safety and Efficacy Study of Intravenous E5564 in Patients with Severe Sepsis
ClinicalTrials.gov Identifier: NCT00046072 - Completed
Sepsis; Shock, Septic; Sepsis Syndrome; Septicemia; Infection
- Alterations of Immunologic Mediators During Severe Sepsis
ClinicalTrials.gov Identifier: NCT00484146 - Recruiting
Severe Sepsis
- Protocol-Driven Hemodynamic Support for Patients With Septic Shock
ClinicalTrials.gov Identifier: NCT00335907 - Recruiting
Shock, Septic; Severe Sepsis; Sepsis
- Effects of Endotoxin in Normal Human Volunteers
ClinicalTrials.gov Identifier: NCT00001303 - Active, not recruiting
Healthy; Lung Disease; Sepsis; Septic Shock
- Prevention of Perinatal Sepsis (PoPS). Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn.
ClinicalTrials.gov Identifier: NCT00136370 - Recruiting
Infant, Newborn, Diseases; Sepsis; Puerperal Infection
- Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-Hematology Patients Presenting Sepsis
ClinicalTrials.gov Identifier: NCT00561639 - Not yet recruiting
Hematologic Diseases; Sepsis
- Statins for the Early Treatment of Sepsis
ClinicalTrials.gov Identifier: NCT00528580 - Not yet recruiting
Sepsis
- Microcirculation Guided Therapy Versus “Standard Treatment” of Severe Sepsis
ClinicalTrials.gov Identifier: NCT00484133 - Recruiting
Severe Sepsis; Microcirculation
- Muscle Atrophy in Sepsis
ClinicalTrials.gov Identifier: NCT00583206 - Recruiting
Atrophy; Sepsis; Weakness
- Multicenter, Double-Blind, Placebo-Controlled Study To Evaluate Efficacy & Safety Of TAK-242 In Adults With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00143611 - Completed
Sepsis; Shock, Septic;; Sepsis Syndrome; Respiratory Insufficiency
- Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
ClinicalTrials.gov Identifier: NCT00487656 - Recruiting
Sepsis; Disseminated Intravascular Coagulation
- Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment with Corticosteroids
ClinicalTrials.gov Identifier: NCT00141973 - Recruiting
Procalcitonin, Sepsis,Corticosteroids
- Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
ClinicalTrials.gov Identifier: NCT00368381 - Recruiting
Sepsis; Adrenal Insufficiency
- Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00534287 - Recruiting
Severe Sepsis; Septic Shock
- A Safety and Efficacy Study of Hospitalized Patients with Community-Acquired Pneumonia and Sepsis
ClinicalTrials.gov Identifier: NCT00042588 - Completed
Pneumonia; Sepsis
- A Randomized Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients
ClinicalTrials.gov Identifier: NCT00133978 - Recruiting
Critical Illness; Sepsis; Organ Failure; Hypopertfusion
- Study of Inhaled Nitric Oxide for Preterm Infants
ClinicalTrials.gov Identifier: NCT00016523 - Active, not recruiting
Respiratory Distress Syndrome; Infant, Premature; Sepsis; Pneumonia; Hypertension, Pulmonary
- Cortisol Control of Human Inflammatory Responses to Endotoxin
ClinicalTrials.gov Identifier: NCT00396344 - Active, not recruiting
Sepsis
- Protocolized Care for Early Septic Shock
ClinicalTrials.gov Identifier: NCT00510835 - Not yet recruiting
Sepsis; Severe Sepsis; Septic Shock
- The Procalcitonin And Survival Study
ClinicalTrials.gov Identifier: NCT00271752 - Recruiting
Localized Infection; Sepsis and Complications; Organ Failure
- A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients with Severe Sepsis
ClinicalTrials.gov Identifier: NCT00034476 - Completed
Sepsis
- A Study To Compare The Effects Of The Infusion Of A Sepsis Drug Between Healthy Adults And Adults With Damaged Livers
ClinicalTrials.gov Identifier: NCT00158769 - Completed
Sepsis Septic shock
- GR270773 In The Treatment Of Suspected Or Confirmed Gram-negative Severe Sepsis In Adults
ClinicalTrials.gov Identifier: NCT00089986 - Completed
Sepsis; Septic Shock
- Phase I Study of Vasoactive Intestinal Peptide in Patients with Acute Respiratory Distress Syndrome and Sepsis
ClinicalTrials.gov Identifier: NCT00004494 - Recruiting
Sepsis; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Adult
- The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients with Severe Sepsis
ClinicalTrials.gov Identifier: NCT00045760 - Completed
Sepsis
- Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis
ClinicalTrials.gov Identifier: NCT00049764 - Completed
Sepsis
- Low-Dose Endotoxemia and the Acute Phase Response
ClinicalTrials.gov Identifier: NCT00197899 - Active, not recruiting
Endotoxemia; Sepsis
- The Effects of HIV Protease Inhibitors in Severe Sepsis
ClinicalTrials.gov Identifier: NCT00346580 - Completed
Sepsis
- Chlorhexidine Vaginal and Infant Wash in Pakistan
ClinicalTrials.gov Identifier: NCT00121394 - Recruiting
Sepsis; Pregnancy
- Reconstruction of Monocytic Immunocompetence by GM-CSF in Patients With Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00252915 - Completed
Sepsis Immunoparalysis
- Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis
ClinicalTrials.gov Identifier: NCT00430859 - Completed
Sepsis; Multiple Organ Dysfunction Syndrome
- The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death
ClinicalTrials.gov Identifier: NCT00568737 - Completed
Sepsis
- A Non-Invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.
ClinicalTrials.gov Identifier: NCT00398736 - Active, not recruiting
Severe Sepsis; Septic Shock
- Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants
ClinicalTrials.gov Identifier: NCT00189384 - Active, not recruiting
Bacterial Infection; Sepsis; Infant, Newborn
- Prophylactic Heparin during Xigris [Drotrecogin Alfa (Activated)] Treatment of High-Risk Severe Sepsis
ClinicalTrials.gov Identifier: NCT00049777 - Completed
Sepsis
- The CRISIS Prevention Study
ClinicalTrials.gov Identifier: NCT00395161 - Recruiting
Sepsis
- Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00185783 - Completed
Sepsis; Relative Adrenal Insufficiency
- Infection Surveillance in Intensive Care Patients
ClinicalTrials.gov Identifier: NCT00197847 - Active, not recruiting
Infection; Pneumonia; Sepsis; Cross Infection
- Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants
ClinicalTrials.gov Identifier: NCT00005888 - Completed
Necrotizing Enterocolitis; Sepsis
- Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis
ClinicalTrials.gov Identifier: NCT00037687 - Terminated
Sepsis
- Cysteine Supplementation in Critically Ill Neonates
ClinicalTrials.gov Identifier: NCT00254176 - Recruiting
Sepsis; Bronchopulmonary Dysplasia; Necrotizing Enterocolitis; Retinopathy of Prematurity; Systemic Inflammatory Response Syndrome
- Procalcitonin in Diagnosing Bacteremia in the Emergency Department
ClinicalTrials.gov Identifier: NCT00174122 - Recruiting
Sepsis; Fever
- Impact of Heart Rate Characteristics Monitoring in Neonates
ClinicalTrials.gov Identifier: NCT00307333 - Recruiting
Sepsis
- Effect of Hyperglycemia in PAI-1 Activity and the Relationship with Outcome in Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00159952 - Completed
Severe sepsis; Septic Shock
- Thrombin Generation and Thromboelastography in Non-Overt DIC
ClinicalTrials.gov Identifier: NCT00299949 - Recruiting
Sepsis; Disseminated Intravascular Coagulation
- The AOT (Acridine Orange and Taurolidine) Trial
ClinicalTrials.gov Identifier: NCT00321165 - Recruiting
Parenteral Nutrition; Infection; Sepsis
- The Effect of Etomidate on Patient Outcomes After Single Bolus Doses
ClinicalTrials.gov Identifier: NCT00441792 - Recruiting
Sepsis; Trauma
- Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients
ClinicalTrials.gov Identifier: NCT00304772 - Recruiting
Candidiasis; Sepsis
- Changes in Immunologic Homeostasis of Neonates in the Neonatal Intensive Care Unit
ClinicalTrials.gov Identifier: NCT00524394 - Recruiting
Premature Birth; Sepsis
- Pro-Calcitonin Levels Following Pediatric Cardiac Surgery
ClinicalTrials.gov Identifier: NCT00284570 - Recruiting
Congenital Heart Disease; Sepsis; Infection
- Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00506519 - Recruiting
Disseminated Intravascular Coagulation
- The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients
ClinicalTrials.gov Identifier: NCT00142220 - Completed
Sepsis Syndrome
- Isotonic Versus Hypotonic Fluid for Maintenance IV Therapy
ClinicalTrials.gov Identifier: NCT00457873 - Recruiting
Gastroenteritis; Bronchiolitis; Sepsis; Urinary Tract Infection
- Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
ClinicalTrials.gov Identifier: NCT00113191 - Completed
Nosocomial Infections; Sepsis; Staphylococcal Infections; Candidemia
- Towards a High-Fat Feeding Intervention Study: Identification of Markers for Inflammation and Organ Damage
ClinicalTrials.gov Identifier: NCT00519350 - Recruiting
Systemic Inflammatory Response Syndrome; Sepsis
- An Open Label Study of Severe Sepsis in Adults
ClinicalTrials.gov Identifier: NCT00568893 - Completed
Severe Sepsis
- Therapeutic Zinc in Infant Bacterial Illness
ClinicalTrials.gov Identifier: NCT00347386 - Recruiting
Sepsis; Bacterial Infections; Pneumonia
- Genetic Variation and Immune Responses After Injury
ClinicalTrials.gov Identifier: NCT00294697 - Recruiting
Sepsis; Pneumonia; Trauma; Burn; Injury
- Skeletal Muscle Oxygenation in Critically Ill
ClinicalTrials.gov Identifier: NCT00384644 - Recruiting
Heart Failure; Sepsis; Septic Shock; Cardiogenic Shock
- Botswana Pediatric Respiratory Disease and Bloodstream Infection Study
ClinicalTrials.gov Identifier: NCT00197691 - Recruiting
HIV Infections; Respiratory Tract Diseases; Sepsis
- Cotrimoxazole Versus Vancomycin for Invasive Methicillin-Resistant Staphylococcus Aureus Infections
ClinicalTrials.gov Identifier: NCT00427076 - Recruiting
Staphylococcal Infections; Meningitis; Sepsis; Pneumonia
- Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
ClinicalTrials.gov Identifier: NCT00135473 - Completed
Severe sepsis; Septic Shock
- Biomarker Analysis of Stress
ClinicalTrials.gov Identifier: NCT00527384 - Not yet recruiting
Sepsis
- Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity
ClinicalTrials.gov Identifier: NCT00303082 - Recruiting
Bacterial Vaginosis; Premature Birth; Sepsis; Periventricular Leukomalacia; Bronchopulmonary Dysplasia
- MiCHO Versus EGDT in the Management of Septic Shock
ClinicalTrials.gov Identifier: NCT00535821 - Recruiting
Severe Sepsis; Septic Shock
- Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis
ClinicalTrials.gov Identifier: NCT00406198 - Completed
Bacteremia; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Pneumonia, Bacterial; Shock, Septic; Sepsis
- Acute Renal Failure in the Surgical Intense Care Units - NTUH-SICU-ARF (NSARF) Study
ClinicalTrials.gov Identifier: NCT00451373 - Recruiting
Acute Renal Failure; Sepsis; Postoperative
- Management of Early Onset Neonatal Septicaemia: Selection of Optimal Antibacterial Regimen for Empiric Treatment
ClinicalTrials.gov Identifier: NCT00487019 - Recruiting
Early Onset Neonatal Sepsis
- Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-related Bloodstream Infections
ClinicalTrials.gov Identifier: NCT00027248 - Completed
Sepsis; Bacteremia; Fungemia
- Functional Genomic Influences on Disease Progression and Outcome in Sepsis Due to Pneumonia or Peritonitis
ClinicalTrials.gov Identifier: NCT00131196 - Recruiting
Pneumonia; Peritonitis
Resources
- Blood Culture (Nemours Foundation)
- Blood Cultures (American Association for Clinical Chemistry)
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