Adrenal Gland Disorders |
Adrenal Disease; Disorder |
Clinical Trial: Iodine I-131 Iodocholesterol, its use in adrenal screening
This study is currently recruiting patients.
Purpose
This is a clinical research study using I-131 Iodocholesterol which is an experimental radioactive chemical that when injected into the vein, is picked up in the adrenal glands and permits visualization with gamma imaging devices. These images are used in diagnosing a variety of adrenal abnormalities.Prior to the injection of I-131 Iodocholesterol, the patient will receive perchlorate capsules to block any uptake of I-131 by the thyroid gland if this is deemed important. The patient will continue to take these capsules throughout the period of imaging, which may last up to 1 week. The injection of I-131 Iodocholesterol will be given into a vein and the patient will return for images on at least 1 and possibly 2 occasions between 3-7 days after injection. If the case requires it, the patient may also be given a steroid in tablet form, dexamethasone, to take orally prior to and after the injection to suppress normal adrenal function so that the abnormal tissues can be more easily detected.
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| Adrenal Gland Diseases Adrenal Gland Neoplasms | Drug: I-131 Iodocholesterol | Phase III |
MedlinePlus related topics: Adrenal Gland Disorders; Cancer; Cancer Alternative Therapy; Endocrine Diseases
Study Type: Interventional
Study Design: Diagnostic
Expected Total Enrollment: 125
Study start: December 1988
Eligibility
Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both
Criteria
Location and Contact Information
Texas
University of Texas M.D. Anderson Cancer Center, Houston, Texas, 77030, United States; Recruiting
Anne Stachowiak 713-745-5152 astachow@mdanderson.org
More Information
Record last reviewed: June 2004
Last Updated: October 13, 2004
Record first received: May 23, 2002
ClinicalTrials.gov Identifier: NCT00037843
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- AACE Physician Finder (American Association of Clinical Endocrinologists)
- ACTH (Adrenocorticotropic Hormone) Test (American Association for Clinical Chemistry)

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