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Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients - Article


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Clinical Trial: Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients

This study is currently recruiting patients.

Sponsored by: National Center for Complementary and Alternative Medicine (NCCAM)
Information provided by: National Center for Complementary and Alternative Medicine (NCCAM)

Purpose

The purpose of this trial is to determine whether acupuncture reduces the incidence of hot flashes in women with breast cancer.

Condition Treatment or Intervention Phase
Breast Neoplasms
Hot Flashes
 Procedure: Acupuncture
Phase III

MedlinePlus related topics:  Breast Cancer;   Menopause
Genetics Home Reference related topics:  breast cancer

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Efficacy Study

Official Title: Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients: A Randomized Controlled Trial

Further Study Details: 

Expected Total Enrollment:  70

Hot flashes are a common side effect of treatment for breast and prostate cancer. Opioids produced by the body are associated with these hot flashes. Acupuncture causes a release of endorphins that may affect opioid levels. Several studies have shown significant decreases in hot flashes following acupuncture treatment. This study will expose participants to either acupuncture or placebo to determine the effectiveness of acupuncture in alleviating hot flashes in breast cancer patients.

Participants in this study will be randomly assigned to receive eight sessions of either real or placebo acupuncture over 4 weeks. Participants will monitor their hot flashes in a diary that will be analyzed 6, 13, and 26 weeks after the start of the study. The frequency and severity of hot flashes will be measured. At the end of 4 weeks, participants in the placebo group will be offered real acupuncture.

Eligibility

Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

  • Treatment for breast cancer
  • Average of three or more hot flashes a day
  • Ability to walk

Exclusion Criteria:

  • Surgery; initiation of a new chemotherapy regimen, immunotherapy, or radiotherapy; or initiation or cessation of hormonal therapy during the study or for 3 weeks before the start of the study
  • Pharmacological treatment of hot flashes or use of selective serotonin reuptake inhibitors (unless the dose has been stable for 4 weeks)
  • Skin infections
  • Any acupuncture treatment within the 6 weeks prior to study entry or acupuncture given specifically for the treatment of hot flashes within 6 months prior to study entry

Location and Contact Information

Terri S. Gray-Teasdale, MS      212-639-3305    teasdalt@mskcc.org
Barrie R. Cassileth, PhD      212-639-8629 

New York
      Memorial Sloan-Kettering Cancer Center, New York,  New York,  10021,  United States; Recruiting
Barrie R. Cassileth, PhD,  Principal Investigator
Gabriella D’Andrea, MD,  Principal Investigator
Han Xiao, MD,  Principal Investigator

More Information

Study ID Numbers:  1-R21-CA098565-01
Record last reviewed:  March 2005
Last Updated:  March 24, 2005
Record first received:  April 27, 2004
ClinicalTrials.gov Identifier:  NCT00081965
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 8, 2005

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Page Updated: January 5, 2006
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