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Systemic Lupus Erythematosus |
Sle |
Lupus erythematosus commonly presents with a malar rash. The classic malar rash of lupus extends over the bridge of the nose. Systemic lupus erythematosus (SLE or lupus) is a chronic, potentially debilitating or fatal autoimmune disease in which the immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but often harms the heart, joints (rheumatological), skin, lungs, blood vessels and brain/nervous system ...
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Systemic Lupus Erythematosus Clinical Trials
- Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00076752 - Active, not recruiting
Lupus Erythematosus, Systemic
- Prevention of Atherosclerosis and Heart Disease in Patients with Systemic Lupus Erythematosis (SLE)
ClinicalTrials.gov Identifier: NCT00054938 - Active, not recruiting
Systemic Lupus Erythematosus; Lupus
- GL701 (Prestara™) in Women with Systemic Lupus Erythematosus Receiving Treatment with Glucocorticoids
ClinicalTrials.gov Identifier: NCT00082511 - Active, not recruiting
Systemic Lupus Erythematosus
- Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)
ClinicalTrials.gov Identifier: NCT00065806 - Active, not recruiting
Lupus Erythematosus, Systemic
- A Study to Evaluate the Efficacy and Safety of Rituximab in Patients with Severe Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00137969 - Active, not recruiting
Lupus Erythematosus, Systemic
- Monoclonal Antibody Treatment for Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00046774 - Active, not recruiting
Systemic Lupus Erythematosus
- Role of altered CD40-Ligand gene transcription in systemic lupus erythematosus
ClinicalTrials.gov Identifier: NCT00008749 - Recruiting
Lupus Erythematosus, Systemic
- New Drug that may Protect Function of Reproductive Organs in Girls Receiving Cyclophosphamide for Lupus
ClinicalTrials.gov Identifier: NCT00088244 - Recruiting
Systemic Lupus Erythematosus; Lupus
- Study of GL701 in Men with Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00037128 - Active, not recruiting
Systemic Lupus Erythematosus
- HIPP Learning to Live Better With Lupus: The Health Improvement and Prevention Program in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00188357 - Recruiting
Systemic Lupus Erythematosus
- Phase I Study of Immune Ablation and CD34+ Peripheral Blood Stem Cell Support in Patients With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00017641 - Active, not recruiting
Systemic Lupus Erythematosus
- Treating Systemic Lupus Erythematosus (SLE) Patients with CTLA4-IgG4m (RG2077)
ClinicalTrials.gov Identifier: NCT00094380 - Active, not recruiting
Lupus Erythematosus, Systemic; Lupus Nephritis
- Study of the Predictors of the Course and Early Outcome of Patients With Systemic Lupus Erythematosus: Nature Versus Nurture
ClinicalTrials.gov Identifier: NCT00006134 - Completed
Systemic Lupus Erythematosus
- A Study of Belimumab, a Fully Human Monoclonal Anti-BLyS Antibody, in Subjects With Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00410384 - Recruiting
Systemic Lupus Erythematosus
- A Study of Belimumab, a Fully Human Monoclonal Anti-BLyS Antibody, in Subjects With Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00424476 - Recruiting
Systemic Lupus Erythematosus
- A Study for Patients Previously Enrolled in Study U2971g to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00381810 - Active, not recruiting
Lupus Erythematosus, Systemic
- Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) Prevention
ClinicalTrials.gov Identifier: NCT00189124 - Recruiting
Systemic Lupus Erythematosus
- Allogeneic Blood Stem Cell Transplantation for Patients With Life-Threatening Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00325741 - Recruiting
Lupus Erythematosus, Systemic
- Study of LJP 394 in Lupus Patients with History of Renal Disease
ClinicalTrials.gov Identifier: NCT00089804 - Recruiting
Lupus Erythematosus, Systemic; Lupus Nephritis
- Serologically Active, Clinically Stable Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00000421 - Completed
Systemic Lupus Erythematosus
- Randomized Study of Oral Contraceptives or Hormone Replacement Therapy in Women With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00006133 - Completed
Systemic Lupus Erythematosus
- Study of TRU-015 in Subjects With Membranous Nephropathy Secondary to Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00479622 - Recruiting
Systemic Lupus Erythematosus
- Ultraviolet Light Therapy for Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004375 - Recruiting
Systemic Lupus Erythematosus
- A Study of rhuMAb IFNalpha in Adults With Mildly Active Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00541749 - Recruiting
Systemic Lupus Erythematosus
- Humanized LL2IGG to Treat Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00011908 - Completed
Systemic Lupus Erythematosus
- An Open Labeled Pilot Study of Atorvastatin in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00432354 - Recruiting
Systemic Lupus Erythematosus
- Triptorelin for Ovary Protection in Childhood Onset Lupus
ClinicalTrials.gov Identifier: NCT00124514 - Recruiting
SLE; Systemic Lupus Erythematosus
- Study of Individualized Instruction versus Pamphlet in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004756 - Completed
Systemic Lupus Erythematosus
- Cyclophosphamide and rATG/Rituximab in Patients With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00278538 - Recruiting
Systemic Lupus Erythematosus
- Allogeneic Stem Cell Transplantation in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00278590 - Recruiting
Systemic Lupus Erythematosus
- Vitamin D Therapy in Patients With Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00418587 - Recruiting
Systemic Lupus Erythematosus
- A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)
ClinicalTrials.gov Identifier: NCT00539838 - Not yet recruiting
Systemic Lupus Erythematosus
- Epidemiologic Study of Reproductive Outcome in Women with Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004663 - Completed
Systemic Lupus Erythematosus
- Role of Antibodies in Cognitive Dysfunction in Patients with Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00042523 - Completed
Systemic Lupus Erythematosus
- Study of LymphoStat-B in Subjects with Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00071487 - Completed
Lupus Erythematosus, Systemic
- The Reduction of Systemic Lupus Erythematosus Flares :Study PLUS
ClinicalTrials.gov Identifier: NCT00413361 - Recruiting
Systemic Lupus Erythematosus
- Myfortic Versus Azathioprine in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00504244 - Recruiting
Systemic Lupus Erythematosus
- Psychoeducational Approach to Improve Health in Lupus
ClinicalTrials.gov Identifier: NCT00000417 - Completed
Systemic Lupus Erythematosus
- Safety of Estrogens in Lupus: Birth Control Pills
ClinicalTrials.gov Identifier: NCT00000420 - Completed
Systemic Lupus Erythematosus
- Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination with Prednisone
ClinicalTrials.gov Identifier: NCT00119678 - Completed
Systemic Lupus Erythematosus
- Anti-CD20 in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00036491 - Completed
Lupus Erythematosus, Systemic
- Hormonal and Environmental Risk Factors for Developing Systemic Lupus Erythematosus: The Carolina Lupus (CLU) Study
ClinicalTrials.gov Identifier: NCT00342095 - Completed
Systemic Lupus Erythematosus
- Skin Denervation in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00155532 - Completed
Systemic Lupus Erythematosus
- Low Dose Aspirin and Statins for Primary Prevention of Atherosclerosis and Arterial Thromboembolism in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00371501 - Recruiting
Atherosclerosis; Thromboembolism; Systemic Lupus Erythematosus
- Genetic Studies of Lupus
ClinicalTrials.gov Identifier: NCT00071175 - Recruiting
Systemic Lupus Erythematosus
- Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women with Active Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004662 - Completed
Systemic Lupus Erythematosus
- Decoy Receptor 3 (DcR3) Polymorphisms in Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00172666 - Recruiting
Rheumatoid Arthritis; Systemic Lupus Erythematosus
- Lupus Atherosclerosis Prevention Study
ClinicalTrials.gov Identifier: NCT00120887 - Completed
Systemic Lupus Erythematosus
- High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide
ClinicalTrials.gov Identifier: NCT00005778 - Active, not recruiting
Lupus Erythematosus, Systemic
- Study of Epratuzumab in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00383513 - Recruiting
Systemic Lupus Erythematosus
- Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease
ClinicalTrials.gov Identifier: NCT00188188 - Recruiting
Systemic Lupus Erythematosus
- Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
ClinicalTrials.gov Identifier: NCT00198068 - Recruiting
Systemic Lupus Erythematosus; Antiphospholipid Syndrome
- Study of Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00001372 - Recruiting
Lupus Nephritis; Systemic Lupus Erythematosus
- Insulin Resistance and Atherosclerosis in a Sample of Women With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00544102 - Recruiting
Systemic Lupus Erythematosus; Insulin Resistance; Atherosclerosis; Abnormal Glucose Metabolism; Cardiac Risk Factors
- Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)
ClinicalTrials.gov Identifier: NCT00230035 - Recruiting
Systemic Lupus Erythematosus
- Immune Ablation and Hematopoietic Stem Cell Support in Patients With Systemic Lupus Erythematosus: A Phase II Study
ClinicalTrials.gov Identifier: NCT00271934 - Completed
Systemic Lupus Erythematosus
- Analyzing the Association of Gene Variants With Increased Risk of Coronary Heart Disease in Women With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00563082 - Completed
Lupus Erythematosus, Systemic
- Positron Emission Tomography (PET) to Locate Areas of White Blood Cell Activity
ClinicalTrials.gov Identifier: NCT00029926 - Completed
Lupus Erythematosus; Systemic
- Phase II/III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women with Mild to Moderate Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004795 - Completed
Systemic Lupus Erythematosus
- Safety of Estrogens in Lupus: Hormone Replacement Therapy
ClinicalTrials.gov Identifier: NCT00000419 - Terminated
Systemic Lupus Erythematosus
- Abnormalities of B Lymphocytes During Systemic Lupus
ClinicalTrials.gov Identifier: NCT00401141 - Recruiting
Systemic Lupus Erythematosus
- Duke Lupus Registry
ClinicalTrials.gov Identifier: NCT00512694 - Recruiting
Systemic Lupus Erythematosus; Cutaneous Lupus
- Pharmacokinetics Study of Epratuzumab in Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00113971 - Terminated
Lupus Erythematosus, Systemic
- Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders
ClinicalTrials.gov Identifier: NCT00010335 - Recruiting
Systemic Sclerosis; Systemic Lupus Erythematosus; Dermatomyositis; Juvenile Rheumatoid Arthritis; Autoimmune Diseases
- A Study to Evaluate the Safety and Effectiveness of Edratide in the Treatment of Lupus
ClinicalTrials.gov Identifier: NCT00203151 - Suspended
Systemic Lupus Erythematosus
- Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome
ClinicalTrials.gov Identifier: NCT00391924 - Completed
Lupus Erythematosus, Systemic; Sjogren's Syndrome
- The Research Registry for Neonatal Lupus
ClinicalTrials.gov Identifier: NCT00074373 - Recruiting
Neonatal lupus; Systemic Lupus Erythematosus; Sjogren's Syndrome; Congenital heart block
- Phase II Pilot Study of Cytarabine for Refractory Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004643 - Completed
Lupus Erythematosus, Systemic
- Phase II Study of Long-Term Dehydroepiandrosterone for Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00004665 - Completed
Systemic Lupus Erythematosus
- Pilot Study of Rituximab Therapy for Systemic Lupus Erythematosus (SLE) and Vasculitis
ClinicalTrials.gov Identifier: NCT00293072 - Completed
Systemic Lupus Erythematosus; ANCA Associated Vasculitis
- Genetic Study of Lupus Patients and Their Families
ClinicalTrials.gov Identifier: NCT00235378 - Recruiting
Systemic Lupus Erythematosus
- Memory and Attention Problems in Lupus: New Treatment Trial With Modafinil
ClinicalTrials.gov Identifier: NCT00297284 - Recruiting
Systemic Lupus Erythematosus
- Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis
ClinicalTrials.gov Identifier: NCT00430677 - Recruiting
Systemic Lupus Erythematosus
- TNF Blockade With Remicade in Active Lupus Nephritis WHO Class V (TRIAL )
ClinicalTrials.gov Identifier: NCT00368264 - Recruiting
Lupus Erythematosus, Systemic; Lupus Nephritis
- Study of Epratuzumab in Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00111306 - Terminated
Systemic Lupus Erythematosus
- Drug Therapy in Lupus Nephropathy
ClinicalTrials.gov Identifier: NCT00001212 - Completed
Nephrotic Syndrome; Systemic Lupus Erythematosus
- Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody Syndrome
ClinicalTrials.gov Identifier: NCT00010400 - Completed
Systemic Lupus Erythematosus; Antiphospholipid Antibody Syndrome
- A Study to Evaluate the Safety and Tolerability of Multiple IV Doses of an Antibody, in Patients With Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00482989 - Recruiting
Lupus
- Cyclophosphamide in Lupus Nephritis
ClinicalTrials.gov Identifier: NCT00441220 - Recruiting
Systemic Lupus Erythematosus
- European Society of Cutaneous Lupus Erythematosus (EUSCLE)
ClinicalTrials.gov Identifier: NCT00420121 - Not yet recruiting
Systemic or Cutaneous Lupus Erythematosus
- Cyclophosphamide and Fludarabine to Treat Lupus Nephritis
ClinicalTrials.gov Identifier: NCT00001676 - Completed
Glomerulonephritis; Lupus Nephritis; Systemic Lupus Erythematosus
- Study of Families with Twins or Siblings Discordant for Rheumatic Disorders
ClinicalTrials.gov Identifier: NCT00055055 - Recruiting
Rheumatic Diseases; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Scleroderma; Dermatomyositis; Myositis
- Statins and Lupus: Effects of Statins on Clinical Lupus Parameters, Serological Markers and Toll-Like Receptors
ClinicalTrials.gov Identifier: NCT00519363 - Not yet recruiting
Systemic Lupus Erythematosus
- Characteristics and Disease Progression of Mixed Connective Tissue Disease and Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00582881 - Recruiting
Mixed Connective Tissue Disease; Systemic Lupus Erythematosus
- Safety and Efficacy Study of LJP 394 (abetimus sodium) to treat lupus kidney disease
ClinicalTrials.gov Identifier: NCT00035308 - Completed
Immunologic Diseases; Autoimmune Diseases; Systemic Lupus Erythematosus; Lupus Nephritis; Lupus Glomerulonephritis
- Six month clinical research study for patients with moderate or severe dry eye syndrome
ClinicalTrials.gov Identifier: NCT00025818 - Completed
Keratoconjunctivitis Sicca; Sjogren's Syndrome; Lupus Erythematosus, Systemic; Arthritis, Rheumatoid; Scleroderma, Systemic
- Memantine in Systemic Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00181298 - Not yet recruiting
Systemic Lupus Erythematosus
- Efficacy of Faslodex in Treatment of SLE Clinical, Serologic, and Molecular Studies
ClinicalTrials.gov Identifier: NCT00417430 - Active, not recruiting
Systemic Lupus Erythematosus
- Feasibility and Safety of Acupuncture for Systemic Lupus
ClinicalTrials.gov Identifier: NCT00493753 - Completed
Systemic Lupus Erythematosus
- Study of Methotrexate in Lupus Erythematosus
ClinicalTrials.gov Identifier: NCT00470522 - Completed
Systemic Lupus Erythematosus
- Estrogen and Gender Biased Autoimmunity
ClinicalTrials.gov Identifier: NCT00519454 - Recruiting
Systemic Lupus Erythematosus
- Study of Epratuzumab in Systemic Lupus Erythematosus (SLE)
ClinicalTrials.gov Identifier: NCT00383214 - Terminated
Systemic Lupus Erythematosus
- Duke Autoimmunity in Pregnancy Registry
ClinicalTrials.gov Identifier: NCT00513591 - Not yet recruiting
Pregnancy; Systemic Lupus Erythematosus; Cutaneous Lupus; Rheumatoid Arthritis; Sjogren's Syndrome; Scleroderma
- Pulse Corticosteroid Therapy and Effect on Brain Water Diffusivity
ClinicalTrials.gov Identifier: NCT00527176 - Recruiting
Systemic Lupus Erythematosus
- Health-Related Quality of Life Measure in Pediatric Lupus
ClinicalTrials.gov Identifier: NCT00280137 - Recruiting
Systemic Lupus Erythematosus; Quality of Life
- Interdisciplinary Study Group of Lupus Erythematosus (ISGLE)
ClinicalTrials.gov Identifier: NCT00420173 - Recruiting
Cutaneous Lupus Erythematosus
- Prevention of Arthritis-Related Work Disability
ClinicalTrials.gov Identifier: NCT00000416 - Completed
Rheumatoid Arthritis; Systemic Lupus Erythematosus; Osteoarthritis, Knee; Ankylosing Spondylitis
- Tacrolimus for the Treatment of Systemic Lupus Erythematosus With Membranous Nephritis
ClinicalTrials.gov Identifier: NCT00125307 - Active, not recruiting
type V (membranous) lupus nephritis
- Effect of Hormone Replacement Therapy on Lupus Activity
ClinicalTrials.gov Identifier: NCT00392093 - Completed
Systemic Lupus Erythematosus
- Effects of Treatment of Chronic Stress in Patients With Lupus
ClinicalTrials.gov Identifier: NCT00483613 - Completed
Systemic Lupus Erythematosus
Resources
- Autoimmune Diseases (Cleveland Clinic)
- Lupus (Cleveland Clinic)
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