This is a training, natural history of disease, and screening protocol for the evaluation, treatment and follow-up of patients with dermatologic diseases and systemic diseases with cutaneous manifestations. Patients enrolled in this protocol will be evaluated and treated according to generally available, standard procedures and therapeutic modalities. Samples of blood and skin will be studied by routine and specialized investigative methods to establish these patients' diagnosis, response to treatment, and/or disease progression.

Condition	Treatment or Intervention
Connective Tissue Disease Skin Disease	Drug: Standard of care treatment

Further Study Details: 

Expected Total Enrollment:  500

This is a training, natural history of disease, and screening protocol for the evaluation, treatment and follow-up of patients with dermatologic diseases and systemic diseases with cutaneous manifestations. Patients enrolled in this protocol will be evaluated and treated according to generally available, standard procedures and therapeutic modalities. Samples of blood and skin will be studied by routine and specialized investigative methods to establish these patients' diagnosis, response to treatment, and/or disease progression.

Genders Eligible for Study:  Both

Criteria

INCLUSION CRITERIA:
Patients of any age, of both genders, and all racial/ethnic groups with dermatologic diseases or systemic diseases with cutaneous manifestations.
Women of childbearing potential, or who are pregnant or lactating, will undergo tests and procedures, and/or receive medications for which data exists proving minimal risk to the fetus or child. Only tests that are clinically indicated for diagnosis will be performed.
Patients must be referred by a physician.
EXCLUSION CRITERIA:
Patients with cognitive impairment.
Pregnancy or lactation, if this status precludes proposed diagnostic procedures or therapies because of known untoward effects on mother and/or child.

Maryland
      National Cancer Institute (NCI), 9000 Rockville Pike,  Bethesda,  Maryland,  20892,  United States; Recruiting

Study ID Numbers:  960102; 96-C-0102
Record last reviewed:  May 1, 2004
Last Updated:  November 23, 2004
Record first received:  November 3, 1999
ClinicalTrials.gov Identifier:  NCT00001506
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08