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Psychodynamic Therapy For Co-Occurring Borderline Personality Disorder and Alcohol Use Disorder - Article


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Seasonal Affective Disorder

SAD 




Clinical Trial: Psychodynamic Therapy For Co-Occurring Borderline Personality Disorder and Alcohol Use Disorder

This study is currently recruiting patients.
Verified by State University of New York - Upstate Medical University September 2005

Sponsored by: State University of New York - Upstate Medical University
Information provided by: State University of New York - Upstate Medical University
ClinicalTrials.gov Identifier: NCT00145678

Purpose

The purpose of the study is to determine the feasibility and effectiveness of psychodynamic psychotherapy for persons suffering from co-occurring borderline personality disorder and an alcohol use disorder.
Condition Intervention Phase
Borderline Personality Disorder
Alcohol Use Disorder
 Behavior: Psychodynamic Therapy
Phase II

MedlinePlus related topics:  Drug Abuse;   Personality Disorders;   Prescription Drug Abuse

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study

Official Title: Psychodynamic Therapy for Patients with Borderline Personality Disorder and Alcohol Abuse

Further Study Details: 
Primary Outcomes: episodes of self-injury, self-reported alcohol use, inpatient psychiatry days
Secondary Outcomes: depression, dissociation, social and occupational functioning
Expected Total Enrollment:  30

Study start: June 2004

Borderline Personality Disorder (BPD) is a condition that can cause significant distress and increased risk of death. Many persons with BPD also have an alcohol use disorder (AUD) and there is evidence that this can worsen the outcome and course of both disorders.

Psychodynamic therapy (PT) involves one-to-one interactions with a therapist. It aims to promote the development of a coherent identity through addressing unconscious conflicts that underlie BPD and enhancing reflective capacity. PT has been shown to be helpful for BPD, but has not been tested for people who have BPD with co-occurring substance use disorders.

The proposed study is a one-year randomized controlled trial of PT for persons with BPD and co-occurring AUD. This will generate some initial data that can be used to determine the need and feasibility a larger and more definitive outcome study. Subjects who enroll are randomized to either a study group receiving weekly PT or to a control group receiving usual care. There is a target enrollment of 15 subjects in each group and a 12 month duration. Outcome measures are administered by a research assistant at enrollment, and then at 3-month intervals.

The investigators anticipate that the PT group will show trends towards better retention in treatment and greater improvement in self-harm, alcohol use, depression, dissociation, and relationships. If so, this would have important and positive implications for the large group of patients who suffer from BPD and co-occurring AUD.

Eligibility

Ages Eligible for Study:  18 Years   -   45 Years,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

  • Age between 18 and 45 years
  • Meets diagnostic criteria for borderline personality disorder and for active alcohol abuse or dependence
  • At least average intelligence

Exclusion Criteria:

  • Meets diagnostic criteria for antisocial personality disorder, schizophrenia, or schizoaffective disorder

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00145678

Anna Remen, Ph.D.      315-464-3167    remena@upstate.edu

New York
      SUNY Upstate Medical University, University Hospital, Syracuse,  New York,  13210,  United States; Recruiting
Anna Remen, Ph.D.  315-464-3167    remena@upstate.edu 
Robert J Gregory, MD,  Principal Investigator

Study chairs or principal investigators

Robert J. Gregory, M.D.,  Principal Investigator,  State University of New York - Upstate Medical University   

More Information

Publications

Gregory RJ. Thematic stages of recovery in the treatment of borderline personality disorder. Am J Psychother. 2004;58(3):335-48.

Study ID Numbers:  SUNY UMU IRB 4968; 130230-44
Last Updated:  September 2, 2005
Record first received:  September 1, 2005
ClinicalTrials.gov Identifier:  NCT00145678
Health Authority: United States: Institutional Review Board
ClinicalTrials.gov processed this record on 2005-09-06

Resources



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November 23, 2009



Page Updated: October 15, 2009
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