The cause of most Interstitial Lung Diseases (ILDs) is still unknown. Further research, e.g. to determine predisposing genetic factors, is therefore needed. A database with relevant clinical data and DNA/serum samples of ILD patients could facilitate future research on cause of ILDs.

Condition	Intervention
Interstitial Lung Diseases	Procedure: Venipuncture

Further study details as provided by St. Antonius Hospital:

Protocol title: ‘Registration of clinical data and DNA of patients with Interstitial Lung Disease(ILD)’ Rationale: The etiopathogenesis of most Interstitial Lung Diseases (ILDs) is still unknown. Further research, e.g. to determine predisposing genetic factors, is therefore needed. A database with relevant clinical data and DNA/serum samples of ILD patients could facilitate future research on the etiopathogenesis of ILDs.

Objective: Availability of relevant clinical data and DNA/serum samples of ILD patients in a database. Those data can be used for future research.

Study design: A prospective observational study Study population: Patients diagnosed with ILD attending the pulmonology department in participating hospitals.

Intervention: a blood sample is taken from each patient. Furthermore, additional information is collected from the medical file.

Main study parameters/endpoints: DNA and serum sample, demographic variables, medical information, occupational history and hobbies.

Nature and extent of the burden and risks associated with participation, group relatedness: two tubes of blood will be drawn from the patients. The risks of drawing blood from a vein are minimal.

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

Diagnosis of an ILD, as stated by the ATS (American Thoracic Society)

Exclusion Criteria:

-

Please refer to this study by ClinicalTrials.gov identifier  NCT00267800

J.M.M. van den Bosch, M.D.      +31306092424    j.vandenbosch@antonius.net
J.C. Grutters, M.D.      +31306092424    j.grutters@antonius.net

Netherlands
      St. Antonius Hospital, Nieuwegein,  3435CM,  Netherlands
      UMC Utrecht, Utrecht,  3584 CX,  Netherlands
      Mesos Medisch Centrum, Utrecht,  3527 CE,  Netherlands
      Diakonessenhuis, Utrecht,  3508 TG,  Netherlands

Study chairs or principal investigators

J.M.M. van den Bosch, M.D.,  Principal Investigator,  St. Antonius Hospital   
J.C. Grutters, M.D.,  Principal Investigator,  St. Antonius Hospital   

Study ID Numbers:  R05.08/A
Last Updated:  December 20, 2005
Record first received:  December 19, 2005
ClinicalTrials.gov Identifier:  NCT00267800
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
ClinicalTrials.gov processed this record on 2006-01-10