Not Signed In -
Hypertension |
High Blood Pressure; Hypertension/High Blood Pressure |
Clinical Trial: Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH)
This study is currently recruiting patients.
|
Purpose
The purpose of this study is to test whether the addition of inhaled iloprost is safe and effective in patients with idiopathic pulmonary arterial hypertension who are already being treated with the endothelin receptor antagonist bosentan.
| Condition | Intervention | Phase |
|---|---|---|
| Hypertension | Drug: Aerosolized iloprost | Phase IV |
MedlinePlus related topics: High Blood Pressure
Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title: Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension
Further Study Details:
Primary Outcomes: 6 minute walk test
Expected Total Enrollment: 72
Expected Total Enrollment: 72
Eligibility
Ages Eligible for Study: 18 Years - 75 Years, Genders Eligible for Study: Both
Criteria
Inclusion Criteria:
- IPAH
- > 3 months treatment with bosentan
- 6 minute walk distance 150 - 425 m
Exclusion Criteria:
- other forms of pulmonary hypertension
- severe comorbidities
- cotreatment with sildenafil or investigational drugs
Location and Contact Information
Please refer to this study by ClinicalTrials.gov identifier NCT00120380
Marius M Hoeper, MD +49 511 532 0 Ext. 3530 hoeper.marius@mh-hannover.de
Germany
Hannover Medical School, Hannover, 30625, Germany; Recruiting
Marius M Hoeper, MD +49 511 532 0 Ext. 3530 hoeper.marius@mh-hannover.de
Marius M Hoeper, MD, Principal Investigator
Marius M Hoeper, MD, Principal Investigator
Study chairs or principal investigators
Marius M Hoeper, MD, Study Chair, Hannover Medical School
More Information
Study ID Numbers: COMBI
Record last reviewed: June 2005
Last Updated: July 18, 2005
Record first received: July 15, 2005
ClinicalTrials.gov Identifier: NCT00120380
Health Authority: Germany: Federal Institute for Drugs and Medicinal Devices
ClinicalTrials.gov processed this record on 2005-07-26
Record last reviewed: June 2005
Last Updated: July 18, 2005
Record first received: July 15, 2005
ClinicalTrials.gov Identifier: NCT00120380
Health Authority: Germany: Federal Institute for Drugs and Medicinal Devices
ClinicalTrials.gov processed this record on 2005-07-26
Resources
- 'White Coat Hypertension' Common Among Sleep Apnea Patients (American College of Chest Physicians)
- About High Blood Pressure: A Special Message for Women (American Heart Association)
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