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Huntington's Disease |
Huntington disease; Huntington//'s chorea; Huntington//'s disease; Progressive Chorea, Chronic Hereditary (Huntington) |
Huntington's disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. HD is a familial disease, passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene. If a child does not inherit the HD gene, he or she will not develop the disease and cannot pass it to subsequent generations. A person who inherits the HD gene will sooner or later develop the disease. Whether one child inherits the gene has no bearing on whether others will or will not inherit the gene. Some early symptoms of HD are mood swings, depression, irritability or trouble driving, learning new things, remembering a fact, or making a decision.
... Huntington disease is an inherited brain disorder that causes uncontrolled movements, mental and emotional problems, and progressive loss of thinking ability (cognition).
Adult-onset Huntington disease, the most common form of this disorder, usually begins in middle age. There is also an early-onset form that begins in childhood or adolescence. Signs and symptoms of adult-onset Huntington disease can include irritability, depression, small involuntary movements, and trouble learning new information or making decisions. As the disease progresses, involuntary jerking movements (chorea) become more pronounced. The person may have trouble walking, speaking, and swallowing. Thinking and reasoning abilities are also affected. The duration of adult-onset Huntington disease generally ranges from 15 to 25 years.
The clinical features of early-onset Huntington disease often differ from those of the adult-onset form. Signs and symptoms can include slowness, clumsiness, rigidity, loss of developmental milestones (such as motor skills), thick speech, and drooling. Seizures occur in about 25 percent of individuals with the condition. The course of early-onset Huntington disease may be shorter than adult-onset Huntington disease (10 to 15 years).
Rarely, other genetic or acquired disorders can mimic some or all of the signs and symptoms of Huntington disease. ...
Huntington's disease (HD, also Huntington disease), formerly known as Hunt ...
From the WEST scientific·clinical |
From the EAST traditional·alternative |
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Huntington's Disease Symptoms1-2 of 5 more...
Signs and symptoms
... The earliest signs and symptoms of Huntington''s disease often include personality changes and decreased cognitive abilities. You may demonstrate symptoms such as irritability, anger or paranoia or sh...
Source: MayoClinic
Causes ... Huntington''s disease is an inherited condition caused by a single abnormal gene. Doctors refer to the illness as an autosomal dominant disorder because only one copy of the defective gene, inherited ...
Source: MayoClinic
Huntington's Disease Prevention1 of 1
Prevention
... If you have a family history of Huntington''s disease, you may want to consider genetic counseling before starting a family. A blood test can determine the presence of the faulty gene, even before you...
Source: MayoClinic
Huntington's Disease Treatment1-2 of 3 more...
Complications
... After onset of the disease, signs and symptoms continue until death. Though the signs and symptoms vary from person to person, vital functions such as swallowing, eating, speaking and walking usually ...
Source: MayoClinic
Treatment ... Most people who have Huntington''s disease eventually become physically and mentally disabled. As the disease progresses, long-term nursing home care may be necessary. No satisfactory treatment is ava...
Source: MayoClinic
Huntington's Disease Support1 of 1
Coping skills
... Most people with Huntington''s disease eventually need assistance in performing daily functions. You may want to live on your own but can''t take care of tasks necessary for independent living. In the...
Source: MayoClinic
Huntington's Disease Other1-2 of 7 more...
Huntington''s Disease
... Huntington’s disease (HD), also known as Huntington’s chorea, results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes u...
Source: Cleveland Clinic
Overview ... Huntington''s disease (Huntington''s chorea) is a progressive, degenerative disease that causes certain nerve cells in your brain to waste away. As a result, you may experience uncontrolled movements,...
Source: MayoClinic
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Huntington's Disease Articles
- Genes and Disease: Huntington disease
... Huntington disease (HD) is an inherited, degenerative neurological disease that leads to dementia. About 30,000 Americans have HD and about 150,000 more are at risk of inheriting the disease from a pa... - Huntington disease
... Huntington disease is an inherited brain disorder that causes uncontrolled movements, mental and emotional problems, and progressive loss of thinking ability (cognition). Adult-onset Huntington diseas... - Huntington's Disease Information Page
... Huntington's disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of i... - Huntington's Disease: Hope Through Research
... In 1872, the American physician George Huntington wrote about an illness that he called "an heirloom from generations away back in the dim past." He was not the first to describe the disorder, which h...
Resources
- (National Women's Health Information Center, OWH, HHS)
- Chorea Information Page (National Institute of Neurological Diseases and Stroke)
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