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Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache - Article


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Headache

Cluster Headache; Headaches; Tension Headache 



Clinical Trial: Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache

This study is currently recruiting patients.
Verified by Sorlandet Hospital HF August 2005

Sponsored by: Sorlandet Hospital HF
Information provided by: Sorlandet Hospital HF
ClinicalTrials.gov Identifier: NCT00135122

Purpose

The purpose of this study is to determine whether prednisolone is more effective than placebo in the the first six days after initiation of medication withdrawal therapy for medication overuse headache. Another purpose is to study whether patients followed by a neurologist 1 year after withdrawal do better than patients followed by a general practitioners.
Condition Intervention Phase
headache, migraine, analgesics, tension type headache
  Drug: prednisone
 Phase III

MedlinePlus consumer health information 

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study

Official Title: Medication Overuse Headache : A Randomised Double Blind Study of Prednisolone or Placebo in Withdrawal Therapy (Phase 3), and a Randomised 1 Year Follow Up by Neurologist or General Physician After Successful Withdrawal Therapy.

Further Study Details: 

Study start: September 2003;  Expected completion: September 2008
Last follow-up: January 2007;  Data entry closure: January 2007

Eligibility

Ages Eligible for Study:  18 Years   -   70 Years,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria: Chronic daily headache and medication overuse fulfilling IHS-II criteria -

Exclusion Criteria:Pregnancy, age under 18 and over 70 years, major mental disorders

-

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00135122

Åse Daasvand Mygland, MD, Ph.D      +4738073910    aase.mygland@sshf.no

Norway, Vest-Agder
      Sørlandet Sykehus HF, Kristiansand,  Vest-Agder,  4604,  Norway; Recruiting
Svein Gunnar Gundersen, Gundersen  +4738074474    s.g.gundersen@sshf.no 
Magne Geir Bøe, MD,  Principal Investigator

Study chairs or principal investigators

Rolf Salvesen, Professor,  Study Chair,  University of Tromsø   

More Information

Study ID Numbers:  70203
Last Updated:  August 24, 2005
Record first received:  August 24, 2005
ClinicalTrials.gov Identifier:  NCT00135122
Health Authority: Norway: Directorate for Health and Social Affairs
ClinicalTrials.gov processed this record on 2005-08-30


Source: ClinicalTrials.gov
Cache Date: August 31, 2005

Resources



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November 27, 2009


Page Updated: October 15, 2009
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