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Folic Acid |
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Folic acid General Systematic name N-[4(2-Amino-4-hydroxy- pteridin-6-ylmethylamino)- benzoyl]-L(+)-glutamic acid. Other names pteroyl-L-glutamic acid, Vitamin B9, Vitamin M, Folacin Molecular formula C19H19N7O6 SMILES C1=CC(=CC=C1C(=O)NC (CCC(=O)O)C(=O)O) NCC2=CN=C3C(=N2) C(=O)N=C(N3)N Molar mass 441.40 g/mol Appearance yellow-orange crystalline powder CAS number [59-30-3] Properties Density and phase ? g/cm3, solid Solubility in water 8.5 g/100 ml (20 °C) ...
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Folic Acid Clinical Trials
- Relationship Between Folic Acid and Warfarin Metabolism and Effect
ClinicalTrials.gov Identifier: NCT00162409 - Recruiting
Folic Acid Deficiency
- The Effect of Folic Acid on Efficacy of Sulfadoxine-Pyrimethamine in Pregnant Women in Western Kenya
ClinicalTrials.gov Identifier: NCT00130065 - Active, not recruiting
Malaria
- High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed
ClinicalTrials.gov Identifier: NCT00002650 - Active, not recruiting
Rectal Cancer; prevention of colorectal cancer; Colon Cancer
- Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults
ClinicalTrials.gov Identifier: NCT00480207 - Recruiting
Depression
- Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors
ClinicalTrials.gov Identifier: NCT00024310 - Active, not recruiting
Drug Toxicity; unspecified adult solid tumor, protocol specific
- Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps
ClinicalTrials.gov Identifier: NCT00033319 - Active, not recruiting
prevention of colorectal cancer; Colon Cancer; Rectal Cancer
- Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients with End Stage Renal Disease Receiving Hemodialysis
ClinicalTrials.gov Identifier: NCT00004495 - Recruiting
End Stage Renal Disease; Hyperhomocysteinemia
- Folic Acid Supplementation in Gambian Primigravidae
ClinicalTrials.gov Identifier: NCT00120822 - Completed
Malaria
- Efficacy of Weekly Versus Daily Folic Acid Supplementation
ClinicalTrials.gov Identifier: NCT00394862 - Active, not recruiting
Neural Tube Defects
- Prevention of Mood Disorders by Folic Acid Supplementation
ClinicalTrials.gov Identifier: NCT00459264 - Recruiting
Depression; Bipolar Disorder
- Efficacy of Treating First Episode Psychosis With Folic Acid,B12 and B6 in Addition to Antipsychotic Medication
ClinicalTrials.gov Identifier: NCT00202280 - Active, not recruiting
First Episode Psychosis
- Lometrexol Plus Folic Acid in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00033722 - Active, not recruiting
stage IV non-small cell lung cancer; Adenosquamous Cell Lung Cancer; Squamous Cell Lung Cancer; stage IIIB non-small cell lung cancer; ...
- A Study of Pemetrexed and Folic Acid Given Before Surgery (Neoadjuvant Treatment) to Patients With Rectal Cancer.
ClinicalTrials.gov Identifier: NCT00330915 - Recruiting
Rectal Neoplasms
- Folic Acid in Preventing Colorectal Polyps in Patients With Previous Colorectal Polyps
ClinicalTrials.gov Identifier: NCT00512850 - Active, not recruiting
Colorectal Cancer
- SEARCH: Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
ClinicalTrials.gov Identifier: NCT00124072 - Active, not recruiting
Cardiovascular Disease
- Effect of Betaine and Folic Acid on Vascular Function in Healthy Humans
ClinicalTrials.gov Identifier: NCT00102843 - Completed
Healthy; Cardiovascular Diseases
- Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)
ClinicalTrials.gov Identifier: NCT00064753 - Active, not recruiting
Renal transplant recipients
- Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00126347 - Completed
Healthy; Cardiovascular Diseases
- Chemoprevention with Folic Acid
ClinicalTrials.gov Identifier: NCT00018551 - Completed
Colon Cancer; Adenoma; Colonic Polyps
- Bioavailability of Folate from a Mixed Diet Using a Stable Isotope Method
ClinicalTrials.gov Identifier: NCT00130585 - Completed
Folate Bioavailability
- Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma
ClinicalTrials.gov Identifier: NCT00364923 - Recruiting
Peripheral T-Cell Lymphoma
- Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study)
ClinicalTrials.gov Identifier: NCT00452829 - Recruiting
Recurrent Neural Tube Defects
- HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study)
ClinicalTrials.gov Identifier: NCT00106886 - Active, not recruiting
Cardiovascular Disease; Myocardial Infarction; Stroke; Cancer
- Study of Pralatrexate and Gemcitabine With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Lymphoproliferative Malignancies
ClinicalTrials.gov Identifier: NCT00481871 - Recruiting
Relapsed or Refractory Lymphoproliferative Malignancies
- Effect of Folic Acid Treatment in Coronary Artery Disease
ClinicalTrials.gov Identifier: NCT00300352 - Recruiting
Coronary Artery Disease
- Iron Supplementation Among Adolescent Girls in India
ClinicalTrials.gov Identifier: NCT00198848 - Recruiting
Iron deficiency anemia
- Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00096330 - Active, not recruiting
Colon Cancer; Rectal Cancer
- VITATOPS: A Study of VITAmins TO Prevent Stroke
ClinicalTrials.gov Identifier: NCT00097669 - Recruiting
Stroke; Transient Ischemic Attack
- Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo
ClinicalTrials.gov Identifier: NCT00342303 - Active, not recruiting
Fatty Acid Metabolism
- A study to compare the efficacy of intravenous loading doses followed by maintenance treatment with oral ibandronic acid versus zoledronic acid in patients with skeletal metastases experiencing moderate to severe pain.
ClinicalTrials.gov Identifier: NCT00099177 - Active, not recruiting
Pain; Bone Neoplasms; Neoplasm Metastasis
- NO Activity and Diabetic Nephropathy
ClinicalTrials.gov Identifier: NCT00136188 - Recruiting
Prediabetes; Metabolic Syndrome; Healthy Controls
- A study to compare the efficacy of intravenous loading doses followed by maintenance treatment with intravenous ibandronic acid versus zoledronic acid in patients with skeletal metastases experiencing moderate to severe pain.
ClinicalTrials.gov Identifier: NCT00099203 - Active, not recruiting
Pain; Bone Neoplasms; Neoplasm Metastasis
- Dosage Effects of Folic Acid on Blood Folates of Honduran Women
ClinicalTrials.gov Identifier: NCT00207532 - Completed
Spina Bifida and Anencephaly
- Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality: A Randomized Controlled Trial in China
ClinicalTrials.gov Identifier: NCT00133744 - Recruiting
Stillbirths; Early neonatal deaths
- DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's Disease
ClinicalTrials.gov Identifier: NCT00440050 - Active, not recruiting
Alzheimer's Disease
- Double-Blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
ClinicalTrials.gov Identifier: NCT00145327 - Active, not recruiting
Osteoporosis
- The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
ClinicalTrials.gov Identifier: NCT00110604 - Completed
Atherosclerosis; Vascular Disease; Cognitive decline; Hearing Loss; Inflammation; Age-Related Memory Disorder
- On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication
ClinicalTrials.gov Identifier: NCT00161096 - Active, not recruiting
Chronic Use of Acid Suppressive Medication; GORD; GERD; Reflux; Peptic Ulcer
- Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer
ClinicalTrials.gov Identifier: NCT00045006 - Active, not recruiting
Cancer
- The Bread Trial: Effects of Bread Fortified With Folic Acid and Vitamin B12
ClinicalTrials.gov Identifier: NCT00353353 - Completed
Healthy
- Gemcitabine With or Without Pemetrexed Disodium in Treating Patients With Unresectable Stage II, Stage III, or Stage IV Pancreatic Cancer
ClinicalTrials.gov Identifier: NCT00049426 - Active, not recruiting
stage II pancreatic cancer; stage III pancreatic cancer; stage IVB pancreatic cancer; stage IVA pancreatic cancer; adenocarcinoma of the pancreas
- Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress
ClinicalTrials.gov Identifier: NCT00014027 - Recruiting
Healthy
- Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)
ClinicalTrials.gov Identifier: NCT00000621 - Active, not recruiting
Emphysema; Lung Diseases; Lung Diseases, Obstructive; Chronic Obstructive Pulmonary Disease
- Randomized Phase Iii-Study On Valproic Acid In Combination With All-Trans Retinoic Acid, Standard Induction- And Consolidation Therapy In Older Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151255 - Recruiting
Acute myeloid leukemia, age > 60 years
- Efficacy and Safety of Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women with Osteopenia, 45 Years of Age and Older.
ClinicalTrials.gov Identifier: NCT00132808 - Active, not recruiting
Osteopenia (osteoporosis prevention)
- Comparison of the Gastric Acid Suppressive Effects of Esomeprazole and Generic Omeprazole
ClinicalTrials.gov Identifier: NCT00542347 - Recruiting
Gastric Acid
- Randomized Phase Ii-Study On Valproic Acid, All-Trans Retinoic Acid And Their Combination In Induction And Consolidation Therapy As Well As Pegfilgrastim After Consolidation Therapy In Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00151242 - Recruiting
Acute Myeloid Leukemia
- Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification
ClinicalTrials.gov Identifier: NCT00207558 - Completed
Neural Tube Defects - Spina Bifida and Anencephaly
- A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Solid Tumors
ClinicalTrials.gov Identifier: NCT00127127 - Active, not recruiting
Tumors
- Controlled Trial of 4-Aminosalicylic Acid in Patients with Small Bowel Crohn's Disease
ClinicalTrials.gov Identifier: NCT00004423 - Active, not recruiting
Crohn's Disease
- Study of Docosahexaenoic Acid (DHA) Supplementation in Patients with X-Linked Retinitis Pigmentosa
ClinicalTrials.gov Identifier: NCT00004827 - Active, not recruiting
Retinitis Pigmentosa
- An Investigational Drug Study with Suberoylanilide Hydroxamic Acid in Relapsed Diffuse Large B-cell Lymphoma
ClinicalTrials.gov Identifier: NCT00097929 - Active, not recruiting
B-Cell Lymphoma
- Safety and Efficacy Trial with Zoledronic Acid for the Treatment of Paget's Disease of Bone
ClinicalTrials.gov Identifier: NCT00103740 - Active, not recruiting
Paget's Disease of Bone
- Effect of Enalapril Plus Folic Acid on Blood Pressure and Glycometabolism
ClinicalTrials.gov Identifier: NCT00520247 - Completed
Plasma Total Homocysteine Level; Blood Pressure
- Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants
ClinicalTrials.gov Identifier: NCT00004410 - Recruiting
Cholestasis
- A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Malignant Lymphoma
ClinicalTrials.gov Identifier: NCT00127140 - Active, not recruiting
Malignant Lymphoma
- Suberoylanilide Hydroxamic Acid in Treating Patients With Relapsed Non-Hodgkin''s Lymphoma
ClinicalTrials.gov Identifier: NCT00124631 - Active, not recruiting
recurrent adult diffuse large cell lymphoma
- Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment
ClinicalTrials.gov Identifier: NCT00558532 - Recruiting
Morbid Obesity; Cardiovascular Disease; Fatty Acid Levels
- Suberoylanilide Hydroxamic Acid and Capecitabine in Treating Patients with Metastatic Or Unresectable Solid Tumors
ClinicalTrials.gov Identifier: NCT00121277 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Valproic Acid in Treating Patients With Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00075777 - Active, not recruiting
recurrent Kaposi's sarcoma; epidemic Kaposi's sarcoma
- Lactic Acid in the Rectum and Life-Threatening Infection.
ClinicalTrials.gov Identifier: NCT00197938 - Recruiting
Septic Shock
- Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy
ClinicalTrials.gov Identifier: NCT00005634 - Active, not recruiting
Leukemia; Lymphoma; Prostate Cancer; Multiple Myeloma; Eye Cancer
- The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH
ClinicalTrials.gov Identifier: NCT00172250 - Completed
Homocysteine; Coronary Artery Disease
- Dimethylxanthenone Acetic Acid in Treating Patients With Solid Tumors
ClinicalTrials.gov Identifier: NCT00003697 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Pilot Study to Evaluate Nucleic Acid Amplification Methods in the Diagnosis and Management of Active TB
ClinicalTrials.gov Identifier: NCT00023439 - Recruiting
Tuberculosis
- Study of Treatment and Metabolism in Patients With Urea Cycle Disorders
ClinicalTrials.gov Identifier: NCT00004307 - Recruiting
Amino Acid Metabolism, Inborn Errors
- Study of Zoledronic Acid for Patients With Hormone-Sensitive Bone Metastases From Prostate Cancer
ClinicalTrials.gov Identifier: NCT00242567 - Recruiting
Prostate Cancer
- Suberoylanilide Hydroxamic Acid in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer
ClinicalTrials.gov Identifier: NCT00132067 - Active, not recruiting
recurrent ovarian epithelial cancer; peritoneal cavity cancer
- Higher Frequency Zoledronic Acid in the Treatment of Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00263484 - Recruiting
Multiple Myeloma
- Painful HIV Neuropathy and Alpha-Lipoic Acid
ClinicalTrials.gov Identifier: NCT00079807 - Active, not recruiting
HIV; Peripheral Neuropathy
- Ursodesoxycholic Acid in the Treatment of Duodenal Adenomas in FAP Patients.
ClinicalTrials.gov Identifier: NCT00134758 - Recruiting
Adenomatous Polyposis Coli; Adenoma
- Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year
ClinicalTrials.gov Identifier: NCT00424983 - Recruiting
Multiple Myeloma; Breast Cancer
- Twice Weekly TP-HDFL for Recurrent or Metastatic Esophageal Cancer
ClinicalTrials.gov Identifier: NCT00154700 - Completed
Esophageal Cancer
- Clinical and Laboratory Study of Methylmalonic Acidemia
ClinicalTrials.gov Identifier: NCT00078078 - Recruiting
Amino Acid Metabolism; Inborn Errors
- Functional and Molecular Characterisation of Oesophageal Distal Epithelium: Correlations With Acid and Non Acid Reflux
ClinicalTrials.gov Identifier: NCT00231881 - Recruiting
Gastro-Oesophageal Reflux
- Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)
ClinicalTrials.gov Identifier: NCT00410566 - Recruiting
Acid Sphingomyelinase Deficiency; Niemann-Pick Disease
- Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer
ClinicalTrials.gov Identifier: NCT00132002 - Active, not recruiting
Male Breast Cancer; stage IV breast cancer; recurrent breast cancer
- The Effect of Fatty Acid Composition on Energy Intake and Satiety
ClinicalTrials.gov Identifier: NCT00242021 - Active, not recruiting
Obesity
- Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid
ClinicalTrials.gov Identifier: NCT00295646 - Active, not recruiting
Breast Cancer
- Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancer
ClinicalTrials.gov Identifier: NCT00134043 - Active, not recruiting
follicular thyroid cancer; insular thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; Thyroid Cancer
- Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors
ClinicalTrials.gov Identifier: NCT00107458 - Active, not recruiting
childhood brain tumor; childhood meningioma; childhood solid tumor; childhood spinal cord tumors
- 24 Month Extension to Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients(Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00555789 - Recruiting
Kidney Transplantation
- ALIMTA (pemetrexed) in Patients with Locally Advanced or Metastatic Cancer
ClinicalTrials.gov Identifier: NCT00034463 - Completed
Metastases; Cancer
- Nicotinic Acid - Pharmacokinetics, Pharmacodynamics, Receptor Expression
ClinicalTrials.gov Identifier: NCT00176020 - Not yet recruiting
Nicotinic Acid; Flush Symptom; Pharmacodynamic; Pharmacokinetic
- D4T or Abacavir Plus Vitamin Enhancement (DAVE)
ClinicalTrials.gov Identifier: NCT00143702 - Recruiting
Elevated Lactic Acid
- Fatty Acid Binding Protein 2 (FABP2) Ancillary Proposal
ClinicalTrials.gov Identifier: NCT00256633 - Active, not recruiting
Type 2 Diabetes Mellitus
- Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid Suppression
ClinicalTrials.gov Identifier: NCT00444236 - Not yet recruiting
Exercise Triggered Asthma; Gastroesophageal Reflux
- Inhibition of Gastric Acid is the Key to Satisfactory Relief of Symptoms With Esomeprazole in NUD Patients
ClinicalTrials.gov Identifier: NCT00222131 - Active, not recruiting
Indigestion
- Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis
ClinicalTrials.gov Identifier: NCT00004441 - Recruiting
Cystic Fibrosis
- Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy and Pharmacokinetics of Myozyme in Patients with Late-Onset Pompe Disease.
ClinicalTrials.gov Identifier: NCT00158600 - Active, not recruiting
Pompe Disease (Late-onset); Glycogen storage disease type II (GSD-II); Acid Maltase Deficiency Disease; Glycogenosis 2
- Suberoylanilide Hydroxamic Acid in Treating Patients With Relapsed or Refractory Advanced Hodgkin''s Lymphoma
ClinicalTrials.gov Identifier: NCT00132028 - Active, not recruiting
recurrent adult Hodgkin''s lymphoma; stage IV adult Hodgkin''s lymphoma; adult lymphocyte depletion Hodgkin''s lymphoma; ...
- Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months), in Renal Transplant Patients
ClinicalTrials.gov Identifier: NCT00403416 - Active, not recruiting
Kidney Transplantation
- PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS
ClinicalTrials.gov Identifier: NCT00439673 - Active, not recruiting
Myelodysplastic Syndromes
- Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule
ClinicalTrials.gov Identifier: NCT00579410 - Active, not recruiting
Esophagitis; Inflammation; Gastritis; Abdominal Pain; Heartburn
- Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery
ClinicalTrials.gov Identifier: NCT00320619 - Active, not recruiting
Scoliosis; Kyphosis; Lordosis; Spondylitis; Spinal Stenosis
- BVAIT: B-Vitamin Atherosclerosis Intervention Trial
ClinicalTrials.gov Identifier: NCT00114400 - Completed
Atherosclerosis
- Evaluation of Efficacy and Safety of Omacor (Omega-3-Acid Ethyl Esters) as Add-on Therapy in Hypertriglyceridemic Subjects Treated With Antara (Fenofibrate)
ClinicalTrials.gov Identifier: NCT00246636 - Active, not recruiting
Hypertriglyceridemia
- Study on Amino Acid Uptake in Brain Tumors
ClinicalTrials.gov Identifier: NCT00204295 - Active, not recruiting
Brain Neoplasms
- Effects of Fatty Acid Supplementation on Substance Dependent Individuals
ClinicalTrials.gov Identifier: NCT00312455 - Active, not recruiting
Substance-Related Disorders
- A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Solid Tumors
ClinicalTrials.gov Identifier: NCT00373490 - Active, not recruiting
Tumors
Resources
- Acido Fólico Ahora: Antes de que te des cuenta que estás embarazada (National Center on Birth Defects and Developmental Disabilities, CDC)
- Acido Fólico para Bebés Saludables: Campaña Nacional de Acido Fólico (National Center on Birth Defects and Developmental Disabilities, CDC)
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