Not Signed In -
Dialysis |
Renal Dialysis |
Clinical Trial: Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis
This study is not yet open for patient recruitment.
|
Purpose
During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.
| Condition | Intervention |
|---|---|
| Peritoneal Dialysis | Drug: Icodextrin Drug: Physioneal (dialysate) |
MedlinePlus consumer health information
Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Dose Comparison, Crossover Assignment, Efficacy Study
Further Study Details:
Expected Total Enrollment: 15
Study start: September 2005; Expected completion: January 2008
Last follow-up: September 2006; Data entry closure: January 2007
Eligibility
Ages Eligible for Study: 18 Years - 85 Years, Genders Eligible for Study: Both
Criteria
Location and Contact Information
Please refer to this study by ClinicalTrials.gov identifier NCT00119990
Per Ivarsen, MD, PhD +4589495727
Denmark
Deparment of Renal Medicine, Skejby Hospital, Aarhus, 8200, Denmark
Per Ivarsen, MD, PhD +4589495727
Per Ivarsen, Principal Investigator
Per Ivarsen, Principal Investigator
Study chairs or principal investigators
Per Ivarsen, Principal Investigator, Department of Renal Medicine C, Skejby Hospital, Denmark
More Information
Publications
Boon D, Bos WJ, van Montfrans GA, Krediet RT. Acute effects of peritoneal dialysis on hemodynamics. Perit Dial Int. 2001 Mar-Apr;21(2):166-71.
Study ID Numbers: AA20050009
Record last reviewed: July 2005
Last Updated: July 18, 2005
Record first received: July 14, 2005
ClinicalTrials.gov Identifier: NCT00119990
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics
ClinicalTrials.gov processed this record on 2005-07-26
Record last reviewed: July 2005
Last Updated: July 18, 2005
Record first received: July 14, 2005
ClinicalTrials.gov Identifier: NCT00119990
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics
ClinicalTrials.gov processed this record on 2005-07-26
Resources
- Amyloidosis and Kidney Disease (National Institute of Diabetes and Digestive and Kidney Diseases)
- Anemia in Kidney Disease and Dialysis (National Institute of Diabetes and Digestive and Kidney Diseases)
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