Combat Related Stress |
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Clinical Trial: Treatment for Women with Post-Traumatic Stress Disorder Related to Childhood Abuse
This study is currently recruiting patients.
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Purpose
The purpose of this study is to compare the effectiveness of one- and two-component treatments in women with Post-Traumatic Stress Disorder (PTSD) related to childhood abuse.
| Condition | Treatment or Intervention |
|---|---|
| Post-Traumatic Stress Disorders | Behavior: Psychotherapy treatment |
MedlinePlus related topics: Post-Traumatic Stress Disorder
Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study
Official Title: Skills Training, Exposure, and Their Combination in Childhood Abuse PTSD
Expected Total Enrollment: 144
Study start: April 2002
PTSD is a debilitating and often chronic anxiety disorder with serious psychiatric comorbidity. The most common trauma associated with PTSD among women is childhood abuse. PTSD related to childhood abuse may cause problems with emotion regulation and interpersonal functioning. This study will address three domains of PTSD related to childhood abuse: emotion management problems, interpersonal problems, and PTSD symptoms.
Participants in this study will be randomly assigned to 16 sessions of one of three treatments: Skills Training for Affective and Interpersonal Regulation (STAIR), which focuses on helping individuals strengthen and build skills in managing feelings and improving interpersonal relationships; Modified Prolonged Exposure (MPE), which focuses on developing narratives of abuse history and completing an "emotional processing" of the trauma in a safe environment; and a combination of STAIR and MPE. Dropout rates and adverse effects will be measured.
Eligibility
Ages Eligible for Study: 22 Years - 65 Years, Genders Eligible for Study: Female
Criteria
Inclusion Criteria:
- DSM-IV criteria for Post-Traumatic Stress Disorder related to childhood physical and/or sexual abuse by a care-giver
- At least one clear memory of the abuse
- Willing to have all assessments tape recorded and sessions video taped
- Willing to maintain any concurrent treatments for the duration of the study
Exclusion Criteria:
- Bipolar Disorder
- Eating Disorder
- Borderline Personality Disorder
- Active substance abuse or dependence
- Living with the abuser
- Self mutilation
- Pregnancy
Location and Contact Information
New York
NYU Child Study Center Institute for Trauma and Stress, New York, New York, 10016, United States; Recruiting
Marylene Cloitre, PhD, Principal Investigator
More Information
http://www.AboutOurKids.org
Record last reviewed: December 2004
Last Updated: December 21, 2004
Record first received: September 24, 2003
ClinicalTrials.gov Identifier: NCT00069381
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Combat Related Stress (National Women's Health Information Center)
- War Syndromes and Their Evaluation: From the U.S. Civil War to the Persian Gulf War (U.S. Department of Defense)

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