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Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault - Article


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Combat Related Stress

 




Clinical Trial: Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault

This study is currently recruiting patients.

Sponsored by: National Institute of Mental Health (NIMH)
Information provided by: National Institute of Mental Health (NIMH)

Purpose

The purpose of this study is to evaluate the effectiveness of Prolonged Exposure (PE) in treating women with post traumatic stress disorder (PTSD).

Condition Treatment or Intervention Phase
Stress Disorders, Post-Traumatic
 Procedure: Prolonged Exposure Therapy
Phase II
Phase III

MedlinePlus related topics:  Post-Traumatic Stress Disorder

Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study

Official Title: Effectiveness of Treatment for PTSD in Community Agencies

Further Study Details: 

Expected Total Enrollment:  220

Study start: January 2002

PE is a brief cognitive behavioral therapy that can ameliorate symptoms of PTSD, depression, and anxiety in survivors of various types of trauma. PE has been successfully implemented by counselors at a community rape crisis clinic (Women Organized Against Rape [WOAR]) who received extensive training and weekly supervision from PE experts. Such extensive expert involvement is not a practical model for long-term clinical practice in a community-based clinic. Therefore, Part 1 of this study will examine whether counselors at WOAR can maintain their PE implementation success with reduced expert involvement. In Part 2 of this study, PE will be implemented by counselors at another community clinic (Joseph J. Peters Institute [JJPI]) to examine its effectiveness in treating PTSD and to determine the generalizability of training procedures.

Participants in this study are randomly assigned to either PE or to individual and group therapy. Treatment sessions are conducted weekly for 10 to 20 weeks, based on participants' rates of improvement. Participants are assessed before treatment, after 10 weeks, and again in the follow-up phase at 3, 6, 12, and 24 months post-treatment.

Eligibility

Ages Eligible for Study:  18 Years   -   67 Years,  Genders Eligible for Study:  Female

Criteria

Inclusion Criteria:

  • DSM-IV criteria for PTSD at least 12 weeks after sexual assault
  • PTSD symptoms that result from sexual assault and not from another traumatic experience

Exclusion Criteria:

  • DSM-IV criteria for schizophrenia or delusional disorder
  • Unstable bipolar disorder, depression with psychotic features, or depression severe enough to require immediate psychiatric treatment. Clients who are medicated and still meet current criteria for these disorders will be excluded.
  • Substance dependence
  • Continued intimate relationship with the assailant

Location and Contact Information

Elizabeth A. Hembree, Ph.D.      215-746-3327    hembree@mail.med.upenn.edu
Edna B. Foa, Ph.D.      215-746-3327    foa@mail.med.upenn.edu

Pennsylvania
      Center for the Treatment and Study of Anxiety, University of Pennsylvania, Philadelphia,  Pennsylvania,  19104,  United States; Recruiting
Elizabeth A. Hembree, Ph.D.  215-746-3327    hembree@mail.med.upenn.edu 
Elizabeth A. Hembree, Ph.D.,  Principal Investigator

      Women Organized Against Rape (WOAR), Philadelphia,  Pennsylvania,  United States; Recruiting
Tammy A. West, M.S., MFT  215-985-3315 

More Information

Study ID Numbers:  42178-16A2
Record last reviewed:  January 2005
Last Updated:  January 25, 2005
Record first received:  April 4, 2003
ClinicalTrials.gov Identifier:  NCT00057629
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005

Resources



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Page Updated: November 5, 2004
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