Combat Related Stress |
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Clinical Trial: Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault
This study is currently recruiting patients.
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Purpose
The purpose of this study is to evaluate the effectiveness of Prolonged Exposure (PE) in treating women with post traumatic stress disorder (PTSD).
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| Stress Disorders, Post-Traumatic | Procedure: Prolonged Exposure Therapy | Phase II Phase III |
MedlinePlus related topics: Post-Traumatic Stress Disorder
Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study
Official Title: Effectiveness of Treatment for PTSD in Community Agencies
Expected Total Enrollment: 220
Study start: January 2002
PE is a brief cognitive behavioral therapy that can ameliorate symptoms of PTSD, depression, and anxiety in survivors of various types of trauma. PE has been successfully implemented by counselors at a community rape crisis clinic (Women Organized Against Rape [WOAR]) who received extensive training and weekly supervision from PE experts. Such extensive expert involvement is not a practical model for long-term clinical practice in a community-based clinic. Therefore, Part 1 of this study will examine whether counselors at WOAR can maintain their PE implementation success with reduced expert involvement. In Part 2 of this study, PE will be implemented by counselors at another community clinic (Joseph J. Peters Institute [JJPI]) to examine its effectiveness in treating PTSD and to determine the generalizability of training procedures.
Participants in this study are randomly assigned to either PE or to individual and group therapy. Treatment sessions are conducted weekly for 10 to 20 weeks, based on participants' rates of improvement. Participants are assessed before treatment, after 10 weeks, and again in the follow-up phase at 3, 6, 12, and 24 months post-treatment.
Eligibility
Ages Eligible for Study: 18 Years - 67 Years, Genders Eligible for Study: Female
Criteria
Inclusion Criteria:
- DSM-IV criteria for PTSD at least 12 weeks after sexual assault
- PTSD symptoms that result from sexual assault and not from another traumatic experience
Exclusion Criteria:
- DSM-IV criteria for schizophrenia or delusional disorder
- Unstable bipolar disorder, depression with psychotic features, or depression severe enough to require immediate psychiatric treatment. Clients who are medicated and still meet current criteria for these disorders will be excluded.
- Substance dependence
- Continued intimate relationship with the assailant
Location and Contact Information
Edna B. Foa, Ph.D. 215-746-3327 foa@mail.med.upenn.edu
Pennsylvania
Center for the Treatment and Study of Anxiety, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States; Recruiting
Elizabeth A. Hembree, Ph.D., Principal Investigator
Women Organized Against Rape (WOAR), Philadelphia, Pennsylvania, United States; Recruiting
More Information
Record last reviewed: January 2005
Last Updated: January 25, 2005
Record first received: April 4, 2003
ClinicalTrials.gov Identifier: NCT00057629
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Combat Related Stress (National Women's Health Information Center)
- War Syndromes and Their Evaluation: From the U.S. Civil War to the Persian Gulf War (U.S. Department of Defense)

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